Acute Consumption of Bordo Grape Juice and Wine Improves Serum Antioxidant Status in Healthy Individuals and Inhibits Reactive Oxygen Species Production in Human Neuron-Like Cells by Cristiane Copetti, Fernanda Wouters Franco, Eduarda da Rosa Machado, Marcela Bromberger Soquetta, Andréia Quatrin, Vitor de Miranda Ramos, José Cláudio Fonseca Moreira, Tatiana Emanuelli, Cláudia Kaehler Sautter, Neidi Garcia Penna

“…To evaluate differences in cellular response, intracellular reactive species production (DCFH-DA) and metabolic mitochondrial viability (MTT) were assessed after exposure of human neuron-like cells (SH-SY5Y) to juice or wine. Glycemia was reduced after juice or wine consumption, whereas blood levels of uric acid were reduced after juice consumption but increased after wine consumption. …”
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Neuronal subset-specific Pten-deficient mice do not exhibit deficits in sensorimotor gating processes [version 3; peer review: 1 approved, 2 approved with reservations] by Matthew S. Binder, Joaquin N. Lugo, Suzanne O. Nolan

“…However, this behavior has not been examined in the neuronal subset-specific (NS)-Pten knockout (KO) model of ASD. …”
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Translocator Protein (18 kDa) Mapping with [I]-CLINDE in the Quinolinic Acid Rat Model of Excitotoxicity: A Longitudinal Comparison with Microglial Activation, Astrogliosis, and Neuronal Death by Nicolas Arlicot, Claire Tronel, Sylvie Bodard, Lucette Garreau, Brice de la Crompe, Inge Vandevelde, Denis Guilloteau, Daniel Antier, Sylvie Chalon

“…These results show that both neuroinflammation and neuronal loss profiles occurred concomitantly and appeared to be transitory processes. …”
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uN2CpolyG-mediated p65 nuclear sequestration suppresses the NF-κB-NLRP3 pathway in neuronal intranuclear inclusion disease by Yu Shen, Kaiyan Jiang, Dandan Tan, Min Zhu, Yusen Qiu, Pencheng Huang, Wenquan Zou, Jianwen Deng, Zhaoxia Wang, Ying Xiong, Daojun Hong

Subjects: “…Neuronal intranuclear inclusion disease…”
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Antibody-mediated degradation of 4R-tau restores mitochondrial membrane polarization in human induced pluripotent stem cell-derived neurons with the MAPT 10+16 mutation by Dale O. Starkie, Charles Arber, Terry Baker, Daniel J. Lightwood, Selina Wray

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Elimination of olfactory sensory neurons by zinc sulfate inoculation prevents SARS-CoV-2 infection of the brain in K18-hACE2 transgenic mice by Ji-Hun Lee, Eun-Seon Yoo, Na-Won Kim, Won-Yong Shim, Han-Bi Jeong, Dong-Hyun Kim, Young-Jun Park, Sun-Min Seo, Jun-Won Yun, Jun Won Park, Kang-Seuk Choi, Ho-Young Lee, Jun-Young Seo, Ki Taek Nam, Je Kyung Seong, Yang-Kyu Choi

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Abnormal cytoskeletal remodeling but normal neuronal excitability in a mouse model of the recurrent developmental and epileptic encephalopathy-susceptibility KCNB1-p.R312H variant by Alessandro Bortolami, Elena Forzisi Kathera-Ibarra, Anastasia Balatsky, Mansi Dubey, Rusheel Amin, Srinidi Venkateswaran, Stefania Dutto, Ishan Seth, Adam Ashor, Angel Nwandiko, Ping-Yue Pan, David P. Crockett, Federico Sesti

“…Surprisingly, the electrical properties of Kcnb1 R312H(+/+) pyramidal neurons are similar to those of WT neurons, indicating that the arginine to histidine replacement does not affect the conducting properties of the mutant channel. …”
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Spinal neuromodulation using ultra low frequency waveform inhibits sensory signaling to the thalamus and preferentially reduces aberrant firing of thalamic neurons in a model of neuropathic pain by Martyn G. Jones, Martyn G. Jones, Liam A. Matthews, Liam A. Matthews, Scott Lempka, Scott Lempka, Scott Lempka, Nishant Verma, James P. Harris, Stephen B. McMahon

“…In this group, ULF current reduced thalamic neurone discharge rate in 19 of 29 (66%) neurons tested. …”
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High-Dose Neural Stem/Progenitor Cell Transplantation Increases Engraftment and Neuronal Distribution and Promotes Functional Recovery in Rats after Acutely Severe Spinal Cord Injury by Taoyang Yuan, Qian Liu, Jie Kang, Hua Gao, Songbai Gui

“…However, the dose-related effects of the neural stem/precursor cell (NSPC) transplantation on the injury microenvironment, NSPC survival, axonal growth, neuronal distribution, the composition of neurons, oligodendrocytes, and astrocytes in the lesion area and functional recovery have not yet been quantitatively evaluated in the context of severe SCI. …”
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Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2 by Charlotte Laurfelt Munch Rasmussen, Signe Frost Frederiksen, Christian Würtz Heegaard, Maj Schneider Thomsen, Eva Hede, Bartosz Laczek, Jakob Körbelin, Daniel Wüstner, Louiza Bohn Thomsen, Markus Schwaninger, Ole N. Jensen, Torben Moos, Annette Burkhart

“…The vector exerted tropism for BECs and neurons resulting in a widespread NPC2 distribution in the brain with a concomitant reduction of cholesterol in adjacent neurons, presumably not transduced by the vector. …”
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Biochanin A Reduces Inflammatory Injury and Neuronal Apoptosis following Subarachnoid Hemorrhage via Suppression of the TLRs/TIRAP/MyD88/NF-κB Pathway by Ling-yun Wu, Zhen-nan Ye, Zong Zhuang, Yongyue Gao, Chao Tang, Chen-hui Zhou, Chun-xi Wang, Xiang-sheng Zhang, Guang-bin Xie, Jing-peng Liu, Meng-liang Zhou, Chun-hua Hang, Ji-xin Shi

“…Inflammatory injury and neuronal apoptosis participate in the period of early brain injury (EBI) after subarachnoid hemorrhage (SAH). …”
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Neuronal subset-specific Pten-deficient mice do not exhibit deficits in sensorimotor gating processes [version 4; peer review: 1 approved, 2 approved with reservations] by Matthew S. Binder, Joaquin N. Lugo, Suzanne O. Nolan

“…However, this behavior has not been examined in the neuronal subset-specific (NS)-Pten knockout (KO) model of ASD. …”
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Alteration in Oxidative Stress Enzymes and Proteins by Datura metel Stramonium Hydroethanolic Root Extract Promotes Hippocampus and Cerebral Cortex Neurons Damage in Adult Sprague Dawley Rats by oboma YI, Eberechukwu GC

“…Extracts cause cortex and hippocampus neurotoxicity through heightened oxidative stress.Conclusion: Datura metel root extract is a neurotoxic agent and causes depopulation of hippocampus and cerebral cortex neurons. The use of this plant should be highly regulated to reduce neuropathies associated with consumption.Keywords: Datura metel, oxidative stress, neuronal damage…”
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The ameliorative effects of melatonin against BDE-47-induced hippocampal neuronal ferroptosis and cognitive dysfunction through Nrf2-Chaperone-mediated autophagy of ACSL4 degradation by Quan Yuan, Mingwei Wang, Zhaoxiang Zhang, Ruofei Wang, Dechao Wang, Zichun Sang, Pu Zhao, Xiaoli Liu, Xiaoying Zhu, Gaofeng Liang, Hua Fan, Dongmei Wang

“…Moreover, nuclear factor erythroid 2-related factor 2 (Nrf2) activation by melatonin contributed to LAMP2a upregulation and CMA of ACSL4 and subsequent neuronal ferroptosis. Importantly, melatonin, CMA activator CA77.1, and ACSL4 inhibitor rosiglitazone (RSG) administration substantially attenuated neuronal/synaptic injury and cognitive deficits following BDE-47 exposure. …”
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Glymphatic dysfunction and neurodegeneration in ALS: Longitudinal insights from rNLS8 TDP-43 mice by Akram Zamani, Adam K. Walker, David K. Wright

Subjects: “…Motor neuron disease…”
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Adversarial examples detection method based on boundary values invariants by Fei YAN, Minglun ZHANG, Liqiang ZHANG

Subjects: “…deep neuron network…”
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Mechanisms of Cancer-Induced Bone Pain by Wang X, Li L, Wang Y

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Editorial: Spatio-temporal molecular mechanisms regulating synapse function and neural circuit dynamics by Tomohisa Hosokawa, Yoshiyuki Kubota, Yoshiyuki Kubota, Yoshiyuki Kubota, Tetsuya Takano, Tetsuya Takano

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Simulating Organic Thin Film Transistors Using Multilayer Perceptron Regression Models to Enable Circuit Design by Laurie E. Calvet, Sami El‐Nakouzi, Zonglong Li, Yerin Kim, Amer Zaibi, Patryk Golec, Ie Mei Bhattacharyya, Yvan Bonnassieux, Lina Kadura, Benjamin Iñiguez

Subjects: “…artificial neuron circuits…”
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The biological and functional restoration of spinal cord injury by JIAN Feng‐zeng, YANG Qi‐qi, DUAN Wan‐ru

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