Multilayer magnetic skyrmion devices for spiking neural networks by Aijaz H Lone, Daniel N Rahimi, Hossein Fariborzi, Gianluca Setti

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Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease by Jeremy Chataway, Suvankar Pal, Charis Wong, Elizabeth Elliott, Jenna M Gregory, Siddharthan Chandran, Judith Newton, Shuna Colville, Maria Stavrou, Christopher J Weir, Nigel Stallard, Malcolm R Macleod, Michelle Steven, Richard Anthony Parker, Arpan R Mehta, Robert J Swingler, Mahesh K B Parmar, Rachel S Dakin, Jill Williamson

“…Introduction Motor neuron disease (MND) is a rapidly fatal neurodegenerative disease. …”
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Caffeic Acid Phenethyl Ester Protects Neurons Against Oxidative Stress and Neurodegeneration During Traumatic Brain Injury by Nurul Sulimai, Jason Brown, David Lominadze

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An Area-Efficient Integrate-and-Fire Neuron Circuit with Enhanced Robustness against Synapse Variability in Hardware Neural Network by Arati Kumari Shah, Kannan Udaya Mohanan, Jisun Park, Hyungsoon Shin, Eou-Sik Cho, Seongjae Cho

“…Neuron circuits are the fundamental building blocks in the modern neuromorphic system. …”
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Neuroprotective effects of arbutin against oxygen and glucose deprivation-induced oxidative stress and neuroinflammation in rat cortical neurons by Tan Jingjing, Yadav Manoj Kumar, Devi Sushma, Kumar Manish

“…In this study, the neuroprotective potential of arbutin (100 µmol L−1) pre-treatment and post-treatment against oxygen/ glucose deprivation (OGD) and reoxygenation (R) induced ischemic injury in cultured rat cortical neurons was explored. The OGD (60 min) and reoxygenation (24 h) treatment significantly (p < 0.001) compromised the antioxidant defence in cultured neurons. …”
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ClC-3 Expression and Its Association with Hyperglycemia Induced HT22 Hippocampal Neuronal Cell Apoptosis by Feiyan Fan, Tao Liu, Xin Wang, Dongni Ren, Hui Liu, Pengxing Zhang, Zhen Wang, Nan Liu, Qian Li, Yanyang Tu, Jianfang Fu

“…With respect to this, the present work aims to study the variation in chloride/proton exchanger ClC-3 expression and its association with HT22 hippocampal neuronal apoptosis under hyperglycemic condition in vitro. …”
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Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming Factors by Andreas Hermann, Jeong Beom Kim, Sumitra Srimasorn, Holm Zaehres, Peter Reinhardt, Hans R. Schöler, Alexander Storch

“…After four weeks of coculture with PA6 stromal cells, neuronal differentiation of hiPSC1F-NSC and hiPSC2F-NSC was as efficient as iPSC3F-FIB or iPSC4F-FIB. …”
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Oleanolic Acid Induces Differentiation of Neural Stem Cells to Neurons: An Involvement of Transcription Factor Nkx-2.5 by You Ning, Jianhua Huang, Bill Kalionis, Qin Bian, Jingcheng Dong, Junzhen Wu, Xiantao Tai, Shijin Xia, Ziyin Shen

“…Neural stem cells (NSCs) harbor the potential to differentiate into neurons, astrocytes, and oligodendrocytes under normal conditions and/or in response to tissue damage. …”
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A case of neuronal intranuclear inclusion disease (NIID) presenting with hydrocephalus-like clinical features: case report by Yonghong Wang, Yongxiang Li, Wei Pan, Yuezhen Shen, Junxia Li, Ying Liu, Yuhua Peng, Shulai Zhu

Subjects: “…Neuronal intranuclear inclusion disease…”
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Corrigendum to “Neuroprotective Effects of the Sonic Hedgehog Signaling Pathway in Ischemic Injury through Promotion of Synaptic and Neuronal Health” by Sen Yin, Xuemei Bai, Danqing Xin, Tingting Li, Xili Chu, Hongfei Ke, Min Han, Wenqiang Chen, Xingang Li, Zhen Wang

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Protective Mechanism of Electroacupuncture Combined with Enriched Rehabilitative Training on Hippocampal Neurons in Rats with Cerebral Ischemia-Reperfusion Injury by Li GONG, Wei TANG, Zhen QIU, Mengxing LI

“…The cerebral infarction volume was observed via TTC staining. The neuronal apoptotic index was determined by TUNEL method. …”
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High-Frequency Synchronization Improves Firing Rate Contrast and Information Transmission Efficiency in E/I Neuronal Networks by Fang Han, Zhijie Wang, Hong Fan, Yaopeng Zhang

“…It is also found that the global firing rate contrast enhancement can prevent the number of spikes of the neurons measured within the limited time window from being confused by noise, thereby enhancing the information encoding efficiency (quantified by entropy theory here) of the neuronal system. …”
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Corrigendum to “Contribution of Neurons and Glial Cells to Complement-Mediated Synapse Removal during Development, Aging and in Alzheimer’s Disease” by Celia Luchena, Jone Zuazo-Ibarra, Elena Alberdi, Carlos Matute, Estibaliz Capetillo-Zarate

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Red neuronal artificial para la predicción de mortalidad de pacientes con enfermedad renal crónica by Sergio Orlando Escalona González, Yailé Caballero Mota, Yanela Rodríguez Alvarez, Mirna León Acebo, Zoraida Caridad González Milán, Beatriz Ricardo Paez, Katiuska Danay Rodríguez Espinosa

“…Objetivo: Diseñar una red neuronal artificial para la predicción de mortalidad en pacientes con enfermedad renal crónica en hemodiálisis. …”
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Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons by Se-In Lee, Heejin Lim, Na Yeon Kim, Jichang Yu, Joonho Cho, Hyein Lee, Dae Won Moon, Jinsoo Seo

“…Amyloid-β (Aβ), a hallmark of Alzheimer’s disease (AD), is generated from the sequential cleavage of amyloid precursor proteins (APPs) by β- and γ-secretases, primarily within endosomes after APP endocytosis by canonical clathrin-mediated endocytosis in neurons. In this study, we developed a protocol for imaging APP on lipid rafts using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and found that astrocyte ApoE4 contributes to an increase in APP localization on lipid rafts, subsequently elevating Aβ42 synthesis in a clathrin-independent manner in neurons.…”
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Long-Term Spatiotemporal Reconfiguration of Neuronal Activity Revealed by Voltage-Sensitive Dye Imaging in the Cerebellar Granular Layer by Daniela Gandolfi, Jonathan Mapelli, Egidio D’Angelo

“…Understanding the spatiotemporal organization of long-term synaptic plasticity in neuronal networks demands techniques capable of monitoring changes in synaptic responsiveness over extended multineuronal structures. …”
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Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice by Ali Yousefian-Jazi, Suhyun Kim, Jiyeon Chu, Seung-Hye Choi, Phuong Thi Thanh Nguyen, Uiyeol Park, Min-gyeong Kim, Hongik Hwang, Kyungeun Lee, Yeyun Kim, Seung Jae Hyeon, Hyewhon Rhim, Hannah L. Ryu, Grewo Lim, Thor D. Stein, Kayeong Lim, Hoon Ryu, Junghee Lee

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Glycogen homeostasis and mitochondrial DNA expression require motor neuron to muscle TGF-β/Activin signaling in Drosophila by Heidi Bretscher, Michael B. O’Connor

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Low-dose intranasal deferoxamine modulates memory, neuroinflammation, and the neuronal transcriptome in the streptozotocin rodent model of Alzheimer’s disease by Jared M. Fine, Jacob Kosyakovsky, Tate T. Bowe, Katherine A. Faltesek, Benjamin M. Stroebel, Juan E. Abrahante, Michael R. Kelly, Elizabeth A. Thompson, Claire M. Westby, Kiley M. Robertson, William H. Frey, Leah R. Hanson

“…Using RNA-sequencing and pathway analysis, STZ was shown to induce several pathways of cell death and neuroinflammation, and IN DFO engaged multiple transcriptomic pathways involved in hippocampal neuronal survival.DiscussionTo our knowledge this study is the first to assess the transcriptomic pathways and mechanisms associated with either the ICV STZ model or DFO treatment, and the first to demonstrate efficacy at this low dose.…”
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Iconography of abnormal non-neuronal cells in pediatric focal cortical dysplasia type IIb and tuberous sclerosis complex by Joyce Zhang, Deneen Argueta, Xiaoping Tong, Harry V. Vinters, Gary W. Mathern, Carlos Cepeda

“…A common feature of these types of non-neuronal cells is their inability to generate action potentials. …”
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