Diseño conceptual de un robot de rehabilitación de la marcha pseudoestacionario by Jaime Ramos-Rojas, Julio S. Lora-Millan, Juan A. Castano, Juan Carballeira, Pedro R. Fernández, Susana Borromeo

“…Se espera que este sistema favorezca la plasticidad neuronal al aportar mayor libertad al usuario para explorar nuevos patrones de movimiento y aumentar su control motor voluntario y su participación activa, mientras el exoesqueleto se adapta y garantiza su equilibrio y estabilidad. …”
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Connectome-based disentangling of epilepsy networks from insular stereoelectroencephalographic leads by Kathrin Machetanz, Eliane Weinbrenner, Thomas Volkmar Wuttke, Silke Ethofer, Randolph Helfrich, Josua Kegele, Stephan Lauxmann, Michael Alber, Sabine Rona, Marcos Tatagiba, Holger Lerche, Jürgen Honegger, Georgios Naros

“…The propagation of local epileptic activity from the seizure onset zone (SOZ) along neuronal networks determines the semiology of seizures. …”
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Expression pattern of Calbindin-D28k, NeuN proteins, ATOH1 and EN2 genes in the human fetal cerebellum by Phanindra Prasad Poudel, Arnab Ghosh, Chacchu Bhattarai, Saman Pradhan, Nirmal Panthi, Dela Singh Joshi, Shanti Khadka, Sandhya Kumari, Guruprasad Kalthur, R. Vani Lakshmi, Sneha Guruprasad Kalthur

“…This study aims to investigate the expression patterns of Calbindin-D28k, NeuN (neuronal nuclease), ATOH1 (Atonal homolog 1), and EN2 (Engrailed -2) in the human fetal cerebellum. …”
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Corticosterone-induced postpartum depression induces depression-like behavior and impairs hippocampal neurogenesis in adolescent offspring via HPA axis and BDNF-mTOR pathway by Hongxiao Xie, Yanning Jiang, Xiumeng Zhang, Xinran Min, Jiuseng Zeng, Li Chen, Nan Zeng, Rong Liu

“…These results indicated that the behavioral deficits and neuronal damage observed in the offspring of PPD mice may be related to HPA axis dysfunction and inhibition of the BDNF-mTOR pathway. …”
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NMDA Reduces Tau Phosphorylation in Rat Hippocampal Slices by Targeting NR2A Receptors, GSK3β, and PKC Activities by Audrée De Montigny, Ismaël Elhiri, Julie Allyson, Michel Cyr, Guy Massicotte

“…Taken together, these data indicate that NR2A receptor activation may be important in limiting Tau phosphorylation by a PKC/GSK3β pathway and strengthen the idea that these receptors might act as an important molecular device counteracting neuronal cell death mechanisms in various pathological conditions.…”
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Medicinal plants with neuroprotective potential in East African countries: A systematic review by Ibe Michael Usman, Ekom Monday Etukudo, Elna Owembabazi, Wusa Makena, Augustine Oviosun, Makeri Danladi, Vivian Ojiakor, Patrick Maduabuchi Aja, Emeka Anyanwu, Yanurkis Duranones Rosales, Mario Edgar Fernandez Diaz, Josiah Ifie, Ismahil Adekunle Adeniyi, Ilemobayo Victor Fasogbon, Victor Bassey Archibong

“…Key findings included increased levels of glutamine synthetase, Na+/K+ ATPase, calcium ATPase, acetylcholinesterase, catalase, and superoxide dismutase, all of which support enhanced neuronal function and protection against oxidative stress. …”
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GENI as an AMPK Activator Binds α and γ Subunits and Improves the Memory Dysfunction of Alzheimer’s Disease Mouse Models via Autophagy and Neuroprotection by Ying Wang, Lanjie Li, Danni Chen, Jiaheng Shan, Meijuan Yi, Hiroyuki Osada, Minoru Yoshida, Lan Xiang, Jianhua Qi

“…GENI exerts anti-AD efficacy in galactose-induced AD mice and naturally aging mice with AD through neuroprotection and modification of autophagy and neuron inflammation. Moreover, AMPK as the target protein of GENI to produce an anti-AD effect is identified and the ASP148, ASP157, and ASP166 of the AMPK α subunit and lysine (LYS)148, aspartic acid (ASP)156, LYS309, and ASP316 in the AMPK γ subunit as binding sites are confirmed. …”
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Does Clostridium Perfringens Epsilon Toxin Mimic an Auto-Antigen Involved in Multiple Sclerosis? by Marie-Lise Gougeon, Valérie Seffer, Cezarela Hoxha, Elisabeth Maillart, Michel R. Popoff

“…Multiple sclerosis (MS) is a chronic immune-mediated neurological disorder, characterized by progressive demyelination and neuronal cell loss in the central nervous system. Many possible causes of MS have been proposed, including genetic factors, environmental triggers, and infectious agents. …”
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Nanomolar detection of essential amino acid in dairy products using a novel electrochemical sensor based on zinc cobaltite nanoflowers embedded porous 3D reduced graphene oxide by Neethu Sebastian, Wan-Chin Yu, Deepak Balram, Ashish Patel, Deepak Kumar, Virendra Kumar Yadav

“…L-tryptophan (L-Trp) is a vital amino acid that sways neuronal function, immunity, and gut homeostasis, and its accurate detection in food samples is crucial. …”
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Mitochondrial ROS modulate presynaptic plasticity in the drosophila neuromuscular junction by Irina Stavrovskaya, Bethany Kristi Morin, Stephen Madamba, Cliyahnelle Alexander, Alexis Romano, Samia Alam, Lucas Pavlov, Erna Mitaishvili, Pablo M. Peixoto

“…These findings establish a novel framework for understanding the signaling role of mROS in presynaptic structural and functional plasticity, providing insights into redox-based mechanisms of neuronal communication.…”
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Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy by Timothy J Abreo, Emma C Thompson, Anuraag Madabushi, Kristen L Park, Heun Soh, Nissi Varghese, Carlos G Vanoye, Kristen Springer, Jim Johnson, Scotty Sims, Zhigang Ji, Ana G Chavez, Miranda J Jankovic, Bereket Habte, Aamir R Zuberi, Cathleen M Lutz, Zhao Wang, Vaishnav Krishnan, Lisa Dudler, Stephanie Einsele-Scholz, Jeffrey L Noebels, Alfred L George, Atul Maheshwari, Anastasios Tzingounis, Edward C Cooper

“…G256W/+ pyramidal cell KCNQ2 and KCNQ3 immunolabeling was significantly shifted from axon initial segments to neuronal somata. Despite normal mRNA levels, G256W/+ mouse KCNQ2 protein levels were reduced by about 50%. …”
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Transcriptomic and proteomic profiling identifies feline fibrosarcoma as clinically amenable model for aggressive sarcoma subtypes by Mikiyo Weber, Daniel Fuchs, Amiskwia Pöschel, Erin Beebe, Zuzana Garajova, Armin Jarosch, Laura Kunz, Witold Wolski, Lennart Opitz, Franco Guscetti, Mirja C. Nolff, Enni Markkanen

“…While feline FSA are characterized by hyperactive EIF2, TP53 and MYC signaling, immune-related and neuronal pathways emerge as modulators of tumor aggressiveness and immunosuppression. …”
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Aberrant resting-state functional network centrality and cognitive impairment in unmedicated, euthymic bipolar patients by Hong Li, Qijin Wu, Jiahui Wang, Xiaobin Zhang, Huihui Song, Dong Wang

“…Conclusion Our findings highlight abnormal neuronal networks involving multiple frontal brain regions and thalamus, which may contribute to cognitive deficits in individuals with euthymic BD. …”
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Tumor resting-state fMRI connectivity to extralesional brain is associated with cognitive performance in glioma patients by Chuh-Hyoun Na, Hans Clusmann, Martin Wiesmann, Kerstin Jütten, Verena Mainz

“…Discussion and conclusion: Intrinsic functional coupling to the rest of the brain was associated with worse cognitive performance and might relate to pathological tumor-neuron interaction on the macroscale, reflecting the invasive nature of diffusely infiltrating glioma. …”
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Neurotoxic Effect of Myricitrin in Copper-Induced Oxidative Stress Is Mediated by Increased Intracellular Ca²⁺ Levels and ROS/p53/p38 Axis by Ignacija Vlašić, Antonio Krstačić-Galić, Anđela Horvat, Nada Oršolić, Anja Sadžak, Lucija Mandić, Suzana Šegota, Maja Jazvinšćak Jembrek

“…Disrupted copper homeostasis is a known contributor to neuronal dysfunction through oxidative stress induction. …”
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Clinical assessment and transcriptome analysis of host immune responses in a vaccination-challenge study using a glycoprotein G deletion mutant vaccine strain of infectious laryngo... by Gayathri Gopakumar, Mauricio J. C. Coppo, Mauricio J. C. Coppo, Andrés Diaz-Méndez, Carol A. Hartley, Joanne M. Devlin

“…Enriched gene ontologies and pathways that indicated heightened immune responses and impairments to ciliary and neuronal functions, cell junction components, and potential damages to cartilaginous and extracellular components in the trachea of the non-vaccinated-challenged birds were consistent with their severe tracheal pathology compared to the other two groups. …”
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Wheat disease recognition method based on the SC-ConvNeXt network model by Tianliang Dong, Xiao Ma, Bin Huang, Wenyu Zhong, Qingan Han, Qinghai Wu, You Tang

“…Subsequently, the CBAM attention module is integrated into ConvNeXt-T to enhance the model’s feature extraction and generalization capabilities in complex backgrounds, and each attention module’s loss function is improved with a LeakyReLU activation function to prevent neuron deactivation when inputs are negative. Furthermore, by introducing the Focal Loss function, the model addresses the imbalance in the quantity of easy and difficult-to-classify samples. …”
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Different functions of PHF10 isoforms – subunits of the PBAF chromatin remodeling complex by A. A. Sheynov, V. V. Tatarskiy, A. M. Azieva, S. G. Georgieva, N. V. Soshnikova

“…Two of the PHF10 isoforms (PHF10-P) are expressed at a high level in neuronal and myeloid progenitors and are necessary for cell proliferation. …”
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NADPH Oxidase 2-Mediated Insult in the Auditory Cortex of Zucker Diabetic Fatty Rats by Zheng-De Du, Wei Wei, Shukui Yu, Qing-Ling Song, Ke Liu, Shu-Sheng Gong

“…Expression of 8-hydroxy-2-deoxyguanosine (8-OHdG), a marker of DNA oxidative damage, was also increased in the neuronal mitochondria of the auditory cortex of ZDF rats. …”
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Inhibitory Effect of Flavonoid Extract of Lotus Leaf on Alcohol-Induced Gastric Injury by Antioxidant Capacity in Mice by Yi Chen, Qin Li, Zhiping Kuang, Xin Zhao, Ruokun Yi, Xiaowei He, Guangjing Feng

“…The quantitative polymerase chain reaction (qPCR) and Western blot results proved that FELL upregulated the mRNA and protein expressions of SOD1, SOD2, CAT, epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR), neuronal nitric oxide synthase (nNOS), and endothelial nitric oxide synthase (eNOS) and downregulated the expression of inducible nitric oxide synthase (iNOS) in the gastric tissue of mice with gastric injury. …”
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