Altered Forebrain Functional Connectivity and Neurotransmission in a Kinase-Inactive Mouse Model of Autism by Shiyu Tang PhD, Elizabeth M. Powell PhD, Wenjun Zhu MS, Fu-Sun Lo MD, Reha S. Erzurumlu PhD, Su Xu PhD

“…We employed resting-state functional magnetic resonance imaging and in vivo high-resolution proton MR spectroscopy to examine neuronal connectivity and neurotransmission of wild-type, heterozygous Met–Emx1 , and fully inactive homozygous Met–Emx1 mice. …”
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Harnessing silica nanoparticles grafted with ascorbic acid to alleviate oxidative stress and impaired brain activity in rats by Essia Hamdi, Slah Hidouri, Ana-Belén Muniz-Gonzalez, Marwa Kechnebbou, Salem Amara

“…Overall, the study revealed that SiO2-NPs@AA corrected effectively nitric oxide (NO) and monoamine oxidase activities, which confirm their role to preserve neuronal function and mitigate neurotoxicity.…”
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Isosteviol Sodium Promotes Neurological Function Recovery in a Model of Spinal Cord Injury in Rats by Tongxia Zhang, Tao Zhang, Han Yu, Lingyi Chi

“…Results We found that STVNa improved spinal cord functional recovery in rats, as evidenced by enhanced BBB locomotor rating scale, angle of inclination, decreased cavity of spinal cord damage, and neuron death in vivo. In addition, STVNa reduced inflammation in rats following SCI, as demonstrated by a reduction in proinflammatory cytokines such as tumor necrosis factor (TNF)‐α, interleukin (IL)‐6, and interleukin (IL)‐1β. …”
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Neuroprotective and Antiapoptotic Activity of Lineage-Negative Bone Marrow Cells after Intravitreal Injection in a Mouse Model of Acute Retinal Injury by Anna Machalińska, Dorota Rogińska, Ewa Pius-Sadowska, Miłosz P. Kawa, Edyta Paczkowska, Michał Rudnicki, Renata Lejkowska, Bartłomiej Baumert, Barbara Wiszniewska, Bogusław Machaliński

“…The first relates to downregulated genes associated with regulation of neuron cell death and apoptosis, response to oxidative stress/hypoxia and external stimuli, and negative regulation of cell proliferation. …”
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Impacts of home-based physical exercises on the health of people with spinal cord injury: a systematic review by José Igor Vasconcelos de Oliveira, Lúcia Inês Guedes Leite de Oliveira, Manoel da Cunha Costa, Raphael José Perrier-Melo, Mário Antônio de Moura Simim, Saulo Fernandes Melo de Oliveira

“…We observed that the focus of the interventions was the morphological, motor neuron, quality of life and functional aspects. The studies showed improvements in muscle strength and morphology, in the ability to perform daily activities, in quality of life and in functional capacities, with no reported adverse situations. …”
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Pentoxifylline Neuroprotective Effects Are Possibly Related to Its Anti-Inflammatory and TNF-Alpha Inhibitory Properties, in the 6-OHDA Model of Parkinson’s Disease by Kelly Rose Tavares Neves, Hélio Vitoriano Nobre, Luzia Kalyne A. M. Leal, Geanne Matos de Andrade, Gerly Anne de Castro Brito, Glauce Socorro de Barros Viana

“…Furthermore, PTX partially reversed the decrease in DA contents and improved neuronal viability. In addition, decreases in immunostaining for TH and dopamine transporter (DAT) were reversed. …”
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Autoantibodies to NR2A Peptide of the Glutamate/NMDA Receptor in Patients with Seizure Disorders in Neuropsychiatric Systemic Lupus Erythematosus by Yan Yang, Chao Yuan, Shu-qun Shen, Xue-er Wang, Qing-hua Mei, Wen-qing Jiang, Qin Huang

“…N-Methyl-D-aspartate (NMDA) receptors are a subgroup of the glutamate receptor family, whose NR2A subunit was found on neuronal cells (anti-NR2A) in NPSLE patients with different types of epilepsy. …”
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Wall of Resilience: How the Intestinal Epithelium Prevents Inflammatory Onslaught in the GutSummary by Eva Liebing, Susanne M. Krug, Markus F. Neurath, Britta Siegmund, Christoph Becker

“…Intestinal epithelial cells provide a communication platform through which they maintain homeostasis with a spectrum of entities including immune cells, neuronal cells, and connective tissue cells. This homeostasis can be disrupted in disease, such as inflammatory bowel disease. …”
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Knowledge mapping and emerging trends in cognitive impairment associated with chronic pain: A 2000–2024 bibliometric study by Li-yuan Zhao, Guang-fen Zhang, Jian-jun Yang, Yu-gang Diao, Kenji Hashimoto

“…Emerging hotspots and future research trends point towards brain imaging mechanisms and neuronal circuit-mediated processes.…”
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Neuroprotective effects of curculigoside against Alzheimer’s disease via regulation oxidative stress mediated mitochondrial dysfunction in L-Glu-exposed HT22 cells and APP/PS1 mice... by Wenqi Wang, Yidi Qu, Siyu Li, Jinyu Chu, Hongxin Yang, Lirong Teng, Di Wang

“…In this study, the neuroprotective effect of CCG through oxidative stress mediated mitochondrial dysfunction on L-glutamate (L-Glu)-damaged hippocampal neuron cell line (HT22) and APPswe/PSEN1dE9 transgenic (APP/PS1) mice were investigated. …”
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Effect of Aromatherapy using Lavender Oil on Audio and Visual Reaction Time: A Quasi-experimental Study by Saroj Chaudhary, Manjinder Kaur, Suman Sharma, Naren Kurmi, Khushboo Shrimali, Soniya Pipliwal, Muskan Singh

“…Conclusion: The prolongation of ART and VRT indicates the inhibitory effect of the inhalational lavender oil on the central neuron especially in the limbic system, through the activation of GABA (gamma-aminobutyric acid) receptors. …”
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Geographical distribution of eight neuromuscular disorders in the Netherlands based on a nationwide registry by Johanna C.W. Deenen, André L.M. Verbeek, Pieter A. van Doorn, Catharina G. Faber, Anneke J. van der Kooi, Nicolette C. Notermans, Jan J.G.M. Verschuuren, Baziel G.M. van Engelen, Nicol C. Voermans

“…So far, mostly geographical maps of motor neuron diseases have been reported. By using record information from the Dutch nationwide Computer Registry of All Myopathies and Polyneuropathies (CRAMP) we aimed to generate geographical maps for eight disorders predominantly diagnosed in adults. …”
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A robust Parkinson’s disease detection model based on time-varying synaptic efficacy function in spiking neural network by Priya Das, Sarita Nanda, Ganapati Panda, Sujata Dash, Amel Ksibi, Shrooq Alsenan, Wided Bouchelligua, Saurav Mallik

“…Considering these limitations, a time-varying synaptic efficacy function based leaky-integrate and fire neuron model, called SEFRON is used for the detection of PD. …”
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Predictive Clinical-Biological Markers Over the First 3 Years of Nusinersen Treatment in SMA Type 1 Patients by Mihaela Badina, Andrada Mirea, Corina Sporea, Gabriel Cristian Bejan

“…Nusinersen treatment reduced pNF-H levels, reflecting decreased neuronal degradation, increased serum creatinine due to enhanced muscle activity, and improved motor function. …”
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Epigenetic Alterations and an Increased Frequency of Micronuclei in Women with Fibromyalgia by Victoria Menzies, Debra E. Lyon, Kellie J. Archer, Qing Zhou, Jenni Brumelle, Kimberly H. Jones, G. Gao, Timothy P. York, Colleen Jackson-Cook

“…The DM sites included significant biological clusters involved in neuron differentiation/nervous system development, skeletal/organ system development, and chromatin compaction. …”
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Astrocytic HIV-1 Nef Expression Decreases Glutamate Transporter Expression in the Nucleus Accumbens and Increases Cocaine-Seeking Behavior in Rats by Jessalyn Pla-Tenorio, Bethzaly Velazquez-Perez, Yainira Mendez-Borrero, Myrella L. Cruz, Marian T. Sepulveda-Orengo, Richard J. Noel

“…Cocaine and HIV neurotoxins play roles in neuronal damage during neuroHIV progression by disrupting glutamate homeostasis in the brain. …”
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PPAR-γ Promotes Hematoma Clearance through Haptoglobin-Hemoglobin-CD163 in a Rat Model of Intracerebral Hemorrhage by Gaiqing Wang, Tong Li, Shu-na Duan, Liang Dong, Xin-gang Sun, Fang Xue

“…We hypothesized that PPAR-γ might protect against ICH-induced neuronal injury via activating the Hp-Hb-CD163 pathway in a rat ICH model. …”
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Biomaterials used in regeneration of salivary gland in three-dimensional culture system -a systematic review by M. Harinisubasri, Divya Bose, Dineshkumar Thayalan, Rajkumar Krishnan, Rameshkumar Annasamy

“…In 52.9% of the studies, Acinar components were formed along with the duct formation in 52.9% of the studies followed by the formation of the myoepithelial component in 29.4% of the studies with neuronal innervation only in 5.88% of the studies. …”
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Localization of Liv2 as an Immature Hepatocyte Marker in EB Outgrowth by Ikkei Takashimizu, Yoshiki Tanaka, Susumu Yoshie, Yoshiya Kano, Hinako Ichikawa, Li Cui, Naoko Ogiwara, Kohei Johkura, Katsunori Sasaki

“…., localization on the cell membrane, as immature hepatocytes in the developing liver, although there were other types of cells with a different pattern of immunoreactivity that were seen only as a granular pattern in the cytoplasm and without ALB or the neuronal marker nestin. These results suggest that Liv2 may be useful as a surface marker for immature hepatocytes derived from ES cells. …”
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UDP-Induced Phagocytosis and ATP-Stimulated Chemotactic Migration Are Impaired in STIM1−/− Microglia In Vitro and In Vivo by Hye Min Lim, Heo Woon, Jung Woo Han, Yoshihiro Baba, Tomohiro Kurosaki, Min Goo Lee, Joo Young Kim

“…Their chemotactic migration defect was reproduced in vivo in embryonic brain; the aggregated number of STIM1−/− microglia in LPS- (lipopolysaccharide-) injected lesions was much smaller than that in wild-type microglia. Furthermore, the neuron phagoptosis activities of activated microglia were significantly diminished in the STIM1−/− microglia. …”
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