Roles of the developmental regulator unc-62/Homothorax in limiting longevity in Caenorhabditis elegans. by Eric L Van Nostrand, Adolfo Sánchez-Blanco, Beijing Wu, Andy Nguyen, Stuart K Kim

“…Finally, in old age, the intestine shows increased expression of several aberrant genes; these UNC-62 targets are expressed predominantly in neuronal cells in developing animals, but surprisingly show increased expression in the intestine of old animals. …”
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Mechanism of Transcranial Magnetic Stimulation in the Treatment of Neuropathic Pain by SUN Yu-jia, ZHANG Jun-feng, YAN Long, FAN Shi-yu, QIAN Yu-lin, CONG Shan, YU Tao

“…Transcranial magnetic stimulation （TMS），a well-established non-invasive neuromodulation technique，generates brief magnetic pulses that penetrate the skull，inducing changes in cortical neuron potentials. This can influence both the function and structure of the nervous system，providing relief from NP symptoms and improving associated mood disorders. …”
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Neuroprotective Effect of DAHP via Antiapoptosis in Cerebral Ischemia by Yanhua Qin, Weiming Hu, Yang Yang, Zhiying Hu, Weiyun Li, Marong Fang

“…There was also attenuation of neuronal apoptosis with decrement in proteins Bcl-2 and COX-2 expressions. …”
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Luteolin: exploring its therapeutic potential and molecular mechanisms in pulmonary diseases by Jialian Lv, Xinyue Song, Zixin Luo, Duoqin Huang, Li Xiao, Kang Zou

“…Owing to its diverse pharmacological activities, such as anticancer, oxidative stress protection, anti-inflammatory, and neuron-preserving effects, luteolin has attracted attention in research and medicine. …”
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Mass‐Guided Single‐Cell MALDI Imaging of Low‐Mass Metabolites Reveals Cellular Activation Markers by James L. Cairns, Johanna Huber, Andrea Lewen, Jessica Jung, Stefan J. Maurer, Tobias Bausbacher, Stefan Schmidt, Pavel A. Levkin, Daniel Sevin, Kerstin Göpfrich, Philipp Koch, Oliver Kann, Carsten Hopf

“…Translation of single cell results to endogenous microglia in organotypic hippocampal slice cultures indicates that LPS‐activation involves changes of the itaconate‐to‐taurine ratio and alterations in neuron‐to‐glia glutamine‐glutamate shuttling. The data suggests that PRISM‐MS can serve as a standard method in single cell metabolomics, given its capability to characterize larger cell populations and low‐mass metabolites.…”
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Acupuncture Induces Reduction in Limbic-Cortical Feedback of a Neuralgia Rat Model: A Dynamic Causal Modeling Study by Zhen-Zhen Ma, Ye-Chen Lu, Jia-Jia Wu, Xiang-Xin Xing, Xu-Yun Hua, Jian-Guang Xu

“…Based on those results, several regions including AMY, S1, and h were recruited as ROI in dynamic causal modeling (DCM) analysis comparing evidence for different neuronal hypotheses describing the propagation of noxious stimuli in regions of interest and horizontal comparison of effective connections between the model and electroacupuncture groups. …”
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Genetic assessment of apolipoprotein E polymorphism and PRNP genotypes in rapidly progressive dementias in Pakistan by Urwah Rasheed, Minahil Khalid, Aneeqa Noor, Umar Saeed, Rizwan Uppal, Saima Zafar

“…Rapidly progressive dementias (RPDs) are a type of fatal dementias that cause rapid progression of neuronal dysfunction. This study aimed to assess the prevalence of APOE genotypes (ε2, ε3, ε4) and PRNP mutations (E200K, M129V) in the general population of Pakistan because of their association with RPDs, including Rapidly Progressive Alzheimer’s Disease (rpAD) and Creutzfeldt-Jakob Disease (CJD). …”
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The Relationship between Peripheral Nerve Conduction Velocity and Ophthalmological Findings in Type 2 Diabetes Patients with Early Diabetic Retinopathy by Azusa Ito, Hiroshi Kunikata, Masayuki Yasuda, Shojiro Sawada, Keiichi Kondo, Chihiro Satake, Kazuki Hashimoto, Naoko Aizawa, Hideki Katagiri, Toru Nakazawa

“…Nerve conduction velocity (NCV) is an indicator of neuronal damage in the distal segment of the peripheral nerves. …”
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A guide to selecting high-performing antibodies for Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D) for use in Western Blot, immunoprecipi... by Carl Laflamme, Kathleen Southern, Riham Ayoubi, Maryam Fotouhi, Charles Alende

“…Abundantly expressed in the brain and involved in a broad range of cellular processes, PPP2R5D plays an essential role in modulating key neuronal pathways and signalling. Pathogenic mutations in the PPP2R5D gene are linked to clinical symptoms characterized by neurodevelopmental delay, intellectual disability, and autism spectrum disorders. …”
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The Long-Term Outcome Comparison of Different Time-Delayed Kallikrein Treatments in a Mouse Cerebral Ischemic Model by Yaohui Ni, Kefu Cai, Yujie Hu, Chuan-hui Wang, Yuanyuan Zhang, Hua Huang, Xing Su, Jin-hua Gu

“…Additionally, kallikrein treatment at 8 h after MCAO significantly enhanced cell proliferation including neural stem cell and induced differentiation of neural stem cell into mature neuron. Kallikrein treatment starting at 8 h also promoted more angiogenesis than other two treatment regimens, which was associated with AKT-GSK3β-VEGF signaling pathway. …”
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Assessment of the Chemical Diversity and Functional Properties of Secondary Metabolites from the Marine Fungus <i>Asteromyces cruciatus</i> by María Paz González-Troncoso, Catalina Landeta-Salgado, Javiera Munizaga, Ruth Hornedo-Ortega, María del Carmen García-Parrilla, María Elena Lienqueo

“…Additionally, no detrimental effects were observed on a neuronal cell line. These findings highlight the influence of carbon sources on the production of bioactive metabolites and their functional properties, providing valuable insights into the biotechnological potential of <i>A. cruciatus</i>.…”
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Integrated Transcriptome Analysis Reveals Novel Molecular Signatures for Schizophrenia Characterization by Tong Ni, Yu Sun, Zefeng Li, Tao Tan, Wei Han, Miao Li, Li Zhu, Jing Xiao, Huiying Wang, Wenpei Zhang, Yitian Ma, Biao Wang, Di Wen, Teng Chen, Justin Tubbs, Xiaofeng Zeng, Jiangwei Yan, Hongsheng Gui, Pak Sham, Fanglin Guan

“…The analysis identified 184 DREGs forming an interconnected network involved in synaptic plasticity, inflammation, neuronal development, and neurotransmission. DREGs exhibited distinct expression in SCZ‐related brain regions and animal models. …”
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Investigation of PACAP Fragments and Related Peptides in Chronic Retinal Hypoperfusion by Dora Werling, Dora Reglodi, Peter Kiss, Gabor Toth, Krisztina Szabadfi, Andrea Tamas, Zsolt Biro, Tamas Atlasz

“…Pituitary adenylate cyclase activating polypeptide (PACAP) has neuroprotective effects in different neuronal and retinal injuries. Retinal ischemia can be effectively modelled by permanent bilateral common carotid artery occlusion (BCCAO), which causes chronic hypoperfusion-induced degeneration in the entire rat retina. …”
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Parametrization of the dying brain: A case report from ICU bed-side EEG monitoring by Sebastian Zinn, Srdjan Z. Dragovic, Jan A. Kloka, Laurent M. Willems, Sebastian Harder, Stephan Kratzer, Kai D. Zacharowski, Gerhard Schneider, Paul S. García, Matthias Kreuzer

“…Although still fundamentally unique, the neuronal activity present in the dying brain is more similar to REM sleep than any other state we tested. …”
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Advancing Alzheimer's Therapy: Computational strategies and treatment innovations by Jibon Kumar Paul, Abbeha Malik, Mahir Azmal, Tooba Gulzar, Muhammad Talal Rahim Afghan, Omar Faruk Talukder, Samar Shahzadi, Ajit Ghosh

“…Alzheimer's disease (AD) is a multifaceted neurodegenerative condition distinguished by the occurrence of memory impairment, cognitive deterioration, and neuronal impairment. Despite extensive research efforts, conventional treatment strategies primarily focus on symptom management, highlighting the need for innovative therapeutic approaches. …”
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Whole exome sequencing identifies ABHD14A and MRNIP as novel candidate genes for developmental language disorder by Amal Bouzid, Malek Belcadhi, Amal Souissi, Meryam Chelly, Fakher Frikha, Hela Gargouri, Crystel Bonnet, Fida Jebali, Salma Loukil, Christine Petit, Saber Masmoudi, Rifat Hamoudi, Mariem Ben Said

“…Biological functions and interconnections analyses predicted the potential roles of ABHD14A and MRNIP in neuronal development pathways. These results suggest ABHD14A and MRNIP, as putative candidate genes for DLD susceptibility. …”
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Detección de estrés por medio de redes neuronales artificiales en personal sanitario by Carlos Eduardo Cañedo Figueroa, Xóchitl Duque Alarcón, María Teresa Silvia Tinoco Zamudio

“…Se generó un modelo de red neuronal para clasificar datos relacionados con la detección oportuna de problemas de estrés en personal sanitario. …”
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Metabolites derived from medicinal plants modulating voltage-gated sodium channel activity: A systematic review by José Luis Estela-Zape, Mayra Liliana Pizarro-Loaiza, Gabriel Arteaga, Santiago Castaño, Leonardo Fierro

“…Background: Voltage-gated sodium channels (Nav) are critical for generating action potentials in neuronal and muscle tissues. Dysfunction of these channels is associated with neurological disorders such as epilepsy, neuropathic pain, and myopathies. …”
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Environmental Enrichment Induces Changes in Long-Term Memory for Social Transmission of Food Preference in Aged Mice through a Mechanism Associated with Epigenetic Processes by Simona Cintoli, Maria Cristina Cenni, Bruno Pinto, Silvia Morea, Alessandro Sale, Lamberto Maffei, Nicoletta Berardi

“…We found that only EE mice successfully performed the remote memory recall task, showed neuronal activation in OFC, assessed with c-fos immunohistochemistry and early tagging of OFC, assessed with histone H3 acetylation, suggesting a defective system consolidation and early OFC tagging in aged mice which are ameliorated by EE.…”
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Brain 18FDG-PET pattern in cognitively impaired elderly patients with bipolar disorder by Nouredine Saleh, Capucine Blaise, Amina Daoudi, Matthieu Queneau, Karim Fard, Julien Dumurgier, Esteban Munoz-Musat, Emeline Marlinge, Jacques Hugon, Claire Hourregue, Claire Paquet, Emmanuel Cognat

“…FDG-PET elucidates glucose metabolic reductions due to altered neuronal activity in the cerebral cortex, allowing detection and identification of neurodegenerative processes. …”
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