Could Cells from Your Nose Fix Your Heart? Transplantation of Olfactory Stem Cells in a Rat Model of Cardiac Infarction by Cameron McDonald, Alan Mackay-Sim, Denis Crane, Wayne Murrell

“…Neural stem cells from the olfactory mucosa are multipotent, with the capacity to differentiate into developmental fates other than neurons and glia, with evidence of cardiomyocyte differentiation in vitro and after transplantation into the chick embryo. …”
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Unraveling cerebroprotective potential of fenchone: A combined in vivo and in silico exploration of nitric oxide synthase modulation by Bangaru Mamatha, Anka Rao Areti, DSNBK Prasanth, Narender Malothu

“…Histological analysis further corroborated the neuroprotective effects of FEN, demonstrating the structural preservation of neurons in the hippocampal CA1 region. Overall, the results suggest that FEN plays a neuroprotective role in brain ischemia, potentially through the inhibition of NOS, reduction of oxidative stress, and modulation of antioxidants, highlighting the potential of FEN as a therapeutic candidate for ischemic stroke management.…”
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CREB Regulates Experience-Dependent Spine Formation and Enlargement in Mouse Barrel Cortex by Annabella Pignataro, Antonella Borreca, Martine Ammassari-Teule, Silvia Middei

“…Experience modifies synaptic connectivity through processes that involve dendritic spine rearrangements in neuronal circuits. Although cAMP response element binding protein (CREB) has a key function in spines changes, its role in activity-dependent rearrangements in brain regions of rodents interacting with the surrounding environment has received little attention so far. …”
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Phosphodiesterase 4 inhibition as a novel treatment for stroke by Jiahong Zhong, Xihui Yu, Zhuomiao Lin

“…These mechanisms collectively facilitate the recovery of functional neurons, thereby serving as potential therapeutic interventions. …”
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Trimethyltin-Induced Microglial Activation via NADPH Oxidase and MAPKs Pathway in BV-2 Microglial Cells by Da Jung Kim, Yong Sik Kim

“…Trimethyltin (TMT) is known as a potent neurotoxicant that causes neuronal cell death and neuroinflammation, particularly in the hippocampus. …”
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Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation by Adam Aguirre, Carola J. Maturana, Paloma A. Harcha, Juan C. Sáez

“…Consequently, activated microglia and astrocytes release ATP and glutamate, affecting myelinization, neuronal development, and survival. Binding of ligands to TLRs induces a cascade of intracellular events leading to activation of several transcription factors that regulate the expression of many genes involved in inflammation. …”
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Parkinson’s disease and exosomes: from pathogenesis to diagnosis and treatment by A. Mišeikaitė, P. Vaitkienė

“…Although the clinical symptoms, neuronal changes, and various molecular mechanisms involved in this neuropathological disorder have been studied for many years, the diagnosis and treatment of the disease remain challenging. …”
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Dynamic Network-Based Relevance Score Reveals Essential Proteins and Functional Modules in Directed Differentiation by Chia-Chou Wu, Che Lin, Bor-Sen Chen

“…During the differentiation process, the proteins and functional modules with higher relevance scores also became more specific to the neuronal identity. Ultimately, the essential components revealed by the relevance scores may play a role in controlling the direction of differentiation. …”
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The Tao of Hematopoietic Stem Cells: Toward a Unified Theory of Tissue Regeneration by Kevin D. Bunting, Robert G. Hawley

“…However, recent studies have suggested that a subpopulation of HSCs may have the ability to contribute to diverse cell types such as hepatocytes, myocytes, and neuronal cells, especially following induced tissue damage. …”
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Gut–brain axis and environmental factors in Parkinson’s disease: bidirectional link between disease onset and progression by Soo Jung Park, Kyung Won Kim, Eun Jeong Lee

“…From these observations, researchers have hypothesized that α-synuclein accumulation may initiate in the gut and subsequently propagate to the central dopaminergic neurons through the gut–brain axis, leading to Parkinson’s disease. …”
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Roles of Brain Angiotensin II in Cognitive Function and Dementia by Masaki Mogi, Jun Iwanami, Masatsugu Horiuchi

“…We and other groups reported that AT2 receptor activation enhances neuronal differentiation and neurite outgrowth in the brain. …”
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Acute cerebral edema: a lethal neurological complication in a patient with COVID-19 infection. Case report and literature review by M. Puodžiūnaitė, R. Sadeckaitė, A. Čikotienė

“…More serious medical conditions such as cerebral edema, neuronal degeneration, encephalitis, acute disseminated encephalomyelitis, Guillain-Barre syndrome, Bickerstaff’s brainstem encephalitis, Miller-Fisher syndrome, polyneuritis, toxic encephalopathy, and stroke can occur. …”
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The neural codes of conscious perception and working memory by Álvaro Deleglise, Mauricio Cervigni

“…Al final del artículo se sugiere que un código neural de fase, el código theta-gamma, podría ser el mecanismo utilizado por un espacio de trabajo neuronal global para codificar contenidos concientes y retener información en la MT.…”
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Autoimmune Gastrointestinal Paralysis: Failure of Conventional Treatment without Immunomodulation by Craig Weinkauf, Sean McPhillips, Robert Krouse, Ira Levine

“…Patients with neuroendocrine-derived tumors can develop B-cell reactivity towards the tumor with cross-reactivity for neurons located in the submucosal and myenteric ganglia of the ENS. …”
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PiLiMoT: A Modified Combination of LoLiMoT and PLN Learning Algorithms for Local Linear Neurofuzzy Modeling by Atiye Sarabi-Jamab, Babak N. Araabi

“…PLN learning relies on training data, it needs rich training data set and no division test, so it is much faster than LoLiMoT, but it may create adjacent neurons that may lead to singularity in regression matrix. …”
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On the Origin of the Nervous System Based on Studying Sensillae in Acoel Turbellarians (Acoela) by Ya.I. Zabotin, A.I. Golubev

“…Subsequently, both types of cells independently came into contact with the processes of neurons. This feature of acoel sensillae may be a consequence of still weak cell differentiation of these peculiar invertebrates and, at the same time, is a morphological basis for further divergence of two different tissues in higher bilaterally symmetrical animals. …”
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Los códigos neurales de la percepción conciente y la memoria de trabajo by Álvaro Deleglise, Mauricio Cervigni

“…Al final del artículo se sugiere que un código neural de fase, el código theta-gamma, podría ser el mecanismo implementado por un espacio de trabajo neuronal global para codificar contenidos concientes y retener información en la MT.…”
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Wavelet Decomposition-Based AVOA-DELM Model for Prediction of Monthly Runoff Time Series and Its Applications by ZHANG Yajie

“…For the improvement in prediction accuracy of monthly runoff time series,a prediction model is proposed,which combines the wavelet decomposition (WD),African vultures optimization algorithm (AVOA),and deep extreme learning machine (DELM),and it is applied to the monthly runoff prediction of Yale Hydrological Station in Yunnan Province.Specifically,WD decomposes the time-series data of monthly runoff to obtain highly regular subsequence components,and AVOA is employed to optimize the number of neurons in the hidden layers of DELM;then,the WD-AVOA-DELM model is built to predict each subsequence component,and the prediction results are summated and reconstructed to produce the final prediction results of monthly runoff.Meanwhile,models based on the support vector machine (SVM) and BP neural networks are constructed for comparative analysis,including WD-AVOA-SVM,WD-AVOA-BP,AVOA-DELM,AVOA-SVM,and AVOA-BP models.The results reveal that the average absolute percentage error of the WD-AVOA-DELM model for the monthly runoff prediction of Yale Hydrological Station is 3.02%;the prediction error is far less than that of WD-STOA-SVM and WD-AVOA-BP models,and the prediction accuracy is more than one order of magnitude higher than that of AVOA-SVM,AVOA-SVM,and AVOA-BP models.The result indicates that the proposed model has good prediction performance.In this model,WD can scientifically reduce the complexity of runoff series and raise the prediction accuracy;AVOA can effectively optimize the key parameters of DELM and improve the performance of DELM networks.…”
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Optogenetics Neuromodulation of the Nose by Feng Xiang, Shipeng Zhang, Mi Tang, Peijia Li, Hui Zhang, Jiahui Xiong, Qinxiu Zhang, Xinrong Li

“…Recently developed optogenetic technology, which allows high-fidelity control of neuronal activity, has been applied to investigate the neural circuits underlying sensory processing and behavior. …”
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DNA repair in cancer stem cells as a factor for glioma resistance to radiotherapy by Yu. S. Makusheva, G. L. Dianov

“…It accounts for characteristics of these cells, namely, the capability of self-renewal and differentiation into astrocytes, oligodendrocytes, and neurons. Moreover, these cells bear multiple genetic lesions typical of cancer cells. …”
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