Ranking of Search Requests in the Digital Information Retrieval System Based on Dynamic Neural Networks by Viera Bartosova, Svetlana Drobyazko, Sergii Bogachov, Olga Afanasieva, Maria Mikhailova

“…Promising variants of neural network models with binary output function of neurons for synthesis of the optimal evaluation plan with a combinatorial set of criteria by solving the problem of assignment were built. …”
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Esophageal Motility Disorders: Current Concepts of Pathogenesis and Treatment by Peter J Kahrilas

“…Neuromuscular pathology is evident only with achalasia (myenteric plexus neurons destruction). Pharmacological therapies have limited efficacy with achalasia; more limited with DES; and none with the nonspecific motility disorders. …”
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Brain receptor dynamics in early and adult life stress: Gateways to maladaptive coping strategies by Sora Shin

“…The brain receptor molecules are key mediators of these processes, translating neuromodulatory signals into neuronal responses or circuit activity changes that ultimately shape behavioral outcomes. …”
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Evaluation the efficiency of using Artificial Neural Networks in predicting meteorological droughts in north-west of Iran by Arash malekian, mahro dehbozorgi, Amir hoshang ehsani

“…The appropriate structure for the network, based on Multi Layer Perceptron with three hidden layer, Back Propagation algorithm, Sigmoid transfer function and 10 neurons in middle layer. The results show that the artificial neural networks are well able to predict the non-linear relationship between rainfall and drought as it can simulate drought precipitation index values largely consistent with the real values with more than 97% regression and less than 5% error. …”
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Forebrain Ischemia-Reperfusion Simulating Cardiac Arrest in Mice Induces Edema and DNA Fragmentation in the Brain by Christina H. Liu, Shuning Huang, Young R. Kim, Bruce R. Rosen, Philip K. Liu

“…This model is known to induce neuronal death in the hippocampus, striatum, and cortex. …”
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Seismic Design Value Evaluation Based on Checking Records and Site Geological Conditions Using Artificial Neural Networks by Tienfuan Kerh, Yutang Lin, Rob Saunders

“…Initial comparison results show that a neural network model with three neurons in the hidden layer can achieve relatively better performance based on the evaluation index of correlation coefficient or mean square error. …”
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Synaptic plasticity in fronto-insular circuits underlying stress susceptibility and resilience by Devin Rocks, Conor Liston

“…In the short term, stress effects on neuronal activity may be adaptive, but repeated engagement of these adaptations may lead to circuit dysfunction—a phenomenon known as allostatic load. …”
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Astragaloside IV Treats Parkinson’s Disease by Regulating the Proliferation and Differentiation of NSCs through the SHH–Nurr1 Pathway by Zicong Wu, Jianing Zhang, Han Gao, Wentao Li

“…Recently, there has been a surge of interest in enhancing the differentiation of neural stem cells (NSCs) and supplementing dopamine neurons as a potential treatment for Parkinson’s disease, the second most prevalent neurodegenerative disorder. …”
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Cox-2 Plays a Vital Role in the Impaired Anxiety Like Behavior in Colchicine Induced Rat Model of Alzheimer Disease by Susmita Sil, Tusharkanti Ghosh

“…Results indicate that the parameters of anxiety were dependent on neuronal circuitries that were probably sensitive to etoricoxib induced blocking of neurodegeneration. …”
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Aduhelm, a novel anti-amyloid monoclonal antibody, for the treatment of Alzheimer’s Disease: A comprehensive review by Hannah W. Haddad, Garett W. Malone, Nicholas J. Comardelle, Arielle E. Degueure, Salomon Poliwoda, Rachel J. Kaye, Kevin S. Murnane, Adam M Kaye, Alan D. Kaye

“…Studies show Adulhelm may help to restore neurological function in patients with AD by reducing beta-amyloid plaques and reestablishing neuronal calcium permeability. At present, there is concern the magnitude of this drug's benefit may only be statistically significant, although not clinically significant. …”
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Changes in Muscles and Tendons Due to Neural Motor Disorders: Implications for Therapeutic Intervention by A. L. Hof

“…Patients with an upper motor neurone syndrome (CP) suffer from many disabling primary symptoms: spasms, weakness, and loss of dexterity. …”
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A Novel Heterozygous De Novo MORC2 Missense Variant Causes an Early Onset and Severe Neurodevelopmental Disorder by Daniel Arbide, Nour Elkhateeb, Ewa Goljan, Carolina Perez Gonzalez, Anna Maw, Soo-Mi Park

“…MORC2 may have a role in the development of neurones, and dominant variants in this gene have recently been linked with disorders including Charcot-Marie-Tooth type 2Z disease, spinal muscular atrophy and, more recently, a neurodevelopmental syndrome consisting of developmental delay, impaired growth, dysmorphic facies, and axonal neuropathy (DIGFAN), presenting with hypotonia, microcephaly, brain atrophy, intellectual disability, hearing loss, faltering growth, and craniofacial dysmorphism. …”
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A combination of topical and systemic administration of brimonidine is neuroprotective in the murine optic nerve crush model. by Ruta Maciulaitiene, Giedrius Kalesnykas, Dainius Haroldas Pauza, Ingrida Januleviciene

“…Animals were sacrificed seven days post-ONC, and immunohistochemical staining of retinal whole mounts was performed using neuronal NeuN and GFAP staining. Microscopic pictures of the central, middle, and peripheral regions of the retina were taken. …”
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Relationship between Zinc (Zn2+) and Glutamate Receptors in the Processes Underlying Neurodegeneration by Bartłomiej Pochwat, Gabriel Nowak, Bernadeta Szewczyk

“…Due to the fact that the free pool of ion Zn2+ is a cotransmitter in some glutamate neurons; the role of this element in the pathophysiology of a neurodegenerative diseases has been intensively studied. …”
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How close is autophagy-targeting therapy for Alzheimer's disease to clinical use? A summary of autophagy modulators in clinical studies by Sofia Miranda Fernandes, Johanna Mayer, Per Nilsson, Makoto Shimozawa

“…A massive accumulation of autophagic vacuoles in neurons in Alzheimer’s brains evidences autophagy impairment in AD. …”
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Dynamic tracking of objects in the macaque dorsomedial frontal cortex by Rishi Rajalingham, Hansem Sohn, Mehrdad Jazayeri

“…We test the mental simulation hypothesis by combining a naturalistic ball-interception task, large-scale electrophysiology in non-human primates, and recurrent neural network modeling. We find that neurons in the monkeys’ dorsomedial frontal cortex (DMFC) represent task-relevant information about the ball position in a multiplexed fashion. …”
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Utilizing the Novel Developed MLP Techniques to Survey Pile Subsidence via Optimization Algorithms by Augustinus Sieck, Graciela Daniels

“…This research aims to develop the Multilayer Perceptron coupled with the Novel Arithmetic Optimization Algorithm and Biogeography-Based Optimization) to find out the optimal number of hidden layers of neurons within MLP. The Klang Valley Mass Rapid Transit network built in Kuala Lumpur, Malaysia, was chosen to test the piles' settlement and earth properties algorithms. …”
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Translational Approach to Behavioral Learning: Lessons from Cerebellar Plasticity by Guy Cheron, Bernard Dan, Javier Márquez-Ruiz

“…The privileged relationship between the cerebellum and the inferior olive offers an ideal circuit for attempting to integrate the numerous evidences of neuronal plasticity into a translational perspective. …”
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Approaches to the Modulation of Abdominal Pain by Emeran A Mayer, Tony Lembo, Lin Chang

“…Even though the precise mechanisms and sites underlying these alterations remain incompletely understood, plausible targets for the development of effective pharmacological treatments are receptors on peripheral terminals of visceral afferent nerves (opioids and serotonin), ion channels and receptors on dorsal horn neurons within the spinal cord (opioids, glutamate, calcitonin gene-related peptide and neurokinin-1), and supraspinal targets in the brainstem within the limbic system and in the prefrontal cortex (serotonin, catecholamines, dopamine and acetylcholine). …”
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Rodent Models of Developmental Ischemic Stroke for Translational Research: Strengths and Weaknesses by Mariangela Gennaro, Alessandro Mattiello, Tommaso Pizzorusso

“…Timing of the lesion occurrence seems to be critical, as it strongly interferes with neuronal circuit development and determines the way spontaneous plasticity takes place. …”
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