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1861
G6PD deficiency triggers dopamine loss and the initiation of Parkinson’s disease pathogenesis
Published 2025-01-01“…Summary: Loss of dopaminergic neurons in Parkinson’s disease (PD) is preceded by loss of synaptic dopamine (DA) and accumulation of proteinaceous aggregates. …”
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1862
Placode and neural crest origins of congenital deafness in mouse models of Waardenburg-Shah syndrome
Published 2025-01-01“…Instead, our results in neural crest-specific Ednrb mutants implicate a previously unrecognized role for glial support of synapse assembly between auditory neurons and cochlear hair cells. Placode-specific Ednrb mutation also caused impaired hearing, resulting from deficient synaptic transmission. …”
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1863
Homeostasis and metabolism of iron and other metal ions in neurodegenerative diseases
Published 2025-02-01“…However, an imbalance in metal ions, whether excessive or insufficient, is detrimental and can contribute to neuronal death through oxidative stress, ferroptosis, cuproptosis, cell senescence, or neuroinflammation. …”
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1864
The Role of Neuroglia in the Development and Progression of Schizophrenia
Published 2024-12-01“…Although glia were originally thought to be present in the brain only to support neurons in a physical, metabolic and nutritional capacity, it has become apparent that these cells have a variety of important physiological roles and that abnormalities in their function may make significant contributions to the symptoms of schizophrenia. …”
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1865
Designs of Biomaterials and Microenvironments for Neuroengineering
Published 2018-01-01“…In addition, we compose a conductive patterned compounded biomaterial, which could mimic neuronal microenvironment for neuroengineering by concentrating the advantage of such biomaterials.…”
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1866
Periodontal Health and Caries Prevalence Evaluation in Patients Affected by Parkinson's Disease
Published 2012-01-01“…Parkinson's disease (PD) is a progressive neurodegenerative disorder related to the loss or absence of dopaminergic neurons in the brain. These deficits result in slowness of movement, tremor, rigidity, and dysfunction of behaviour. …”
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1867
Neurotoxicological Effects of Some Mycotoxins on Humans Health and Methods of Neuroprotection
Published 2025-01-01“…They are mainly related to the increase in oxidative stress in neuronal cells, which leads to higher levels of pro-inflammatory cytokines as IL-1β, IL-6 and TNF-α, enzymatic activity as GST, GPx, CAT and SOD and neurotransmitter dysfunction (5-HT, serotonin, dopamine and GABA). …”
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1868
Cortical Reorganization following Injury Early in Life
Published 2016-01-01“…Brain reorganization of the gray matter within the CLH, while not necessarily indicating better outcome, is suggested as a response to neuronal deficits following injury early in life.…”
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1869
ROLE OF THE MODULATORY MEDIATOR SEROTONIN IN THE INDUCTION OF EPIGENETIC PROCESSES DURING LONG TERM MEMORY FORMATION IN HELIX
Published 2015-01-01“…Mollusks are a popular model in neurobiology, because they have relatively simple CNSs with giant neurons. Previously, we found strong induction of histone H3 acetylation and methylation during food aversion conditioning in Helix. …”
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1870
Photoreceptor metabolic window unveils eye–body interactions
Published 2025-01-01“…Abstract Photoreceptors are specialized neurons at the core of the retina’s functionality, with optical accessibility and exceptional sensitivity to systemic metabolic stresses. …”
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1871
Simulation and accurate prediction of thermal efficiency of functionalized COOH-MWCNT/water nanofluids by artificial neural network using experimental data
Published 2025-01-01“…To model this data, an ANN with two hidden layers with 7 and 8 neurons in the first and second layers, respectively, is used. …”
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1872
Sleep in Genetically Confirmed Pantothenate Kinase-Associated Neurodegeneration: A Video-Polysomnographic Study
Published 2010-01-01“…Patients show iron accumulation in the basal ganglia, with neuronal loss and gliosis. A mutation of pantothenate kinase (PANK2) gene localized on chromosome 20p13 has been described in familiar forms, as well as in sporadic patients. …”
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1873
Effet de l'illumination proche infra-rouge intracérébrale chez des primates MPTP
Published 2015-03-01“…La maladie de Parkinson (MP) est une maladie neurodégénérative chronique affectant le système dopaminergique et se traduisant par une perte des neurones dopaminergiques (DA) de la substance noire compacta (SNc) et des faisceaux nigro-striés. …”
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1874
Ascorbic acid-containing compound efficacy in ischemic brain damage
Published 2024-09-01“…Results: Preincubation of cortical cells with 10-100 μM of 3-EA leads to inhibition of [Ca2+]i in cytosol of neurons and astrocytes under GluTox and oxygen-glucose deprivation (OGD) conditions. …”
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1875
Effects of Treadmill Exercise on Hippocampal Synaptic Plasticity and Expression of Related Proteins in Aging Mice
Published 2023-06-01“…Nissl staining was used to detect the morphology of hippocampal neurons, Golgi staining was used to detect the number of dendritic spines in the hippocampus. …”
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1876
Role of BDNF-TrkB signaling in the improvement of motor function and neuroplasticity after ischemic stroke in rats by transcranial direct current stimulation
Published 2025-01-01“…Moreover, tDCS can control neuronal excitability, promote axonal regeneration, and accelerate motor function recovery in ischemia reperfusion-injured rats.…”
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1877
Intracalvariosseous injection: an approach for central nervous system drug delivery through skull bone marrow with a preclinical research in strokeResearch in context
Published 2025-02-01“…In the treatment of stroke with neuroprotective agents, although the drug dosage of ICO injection was lower than intravenous injection, drug accumulation in the brain increased after ICO injection, which helped repair nerve damage, reduce neuronal apoptosis, and decrease the expression of inflammatory factors. …”
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1878
Response Features Determining Spike Times
Published 1999-01-01“…Interpreting messages encoded in single neuronal responses requires knowing which features of the responses carry information. …”
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1879
Using cortical organoids to understand the pathogenesis of malformations of cortical development
Published 2025-01-01“…Widespread abnormalities in neuronal formation or migration can lead to small head size or microcephaly with disorganized placement of cell types. …”
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1880
Transspieces Kitchen
Published 2025-02-01“…La arquitectura es la manera en que las diferentes formas de vida ejecutan su entrelazamiento físico, neuronal y metabólico - cómo se constituyen a sí mismas como algo inseparable. …”
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