Adaptation optimizes sensory encoding for future stimuli. by Jiang Mao, Constantin A Rothkopf, Alan A Stocker

“…Sensory neurons continually adapt their response characteristics according to recent stimulus history. …”
Get full text

Chronic cough as a disease by Richard D. Turner, Surinder S. Birring

“…Newer clinical guidelines in essence consider chronic cough as a disease in itself, resulting from afferent neuronal hypersensitivity and central nervous system dysfunction. …”
Get full text

MiRNAs as major players in brain health and disease: current knowledge and future perspectives by Sarika V. Kapplingattu, Sujata Bhattacharya, Yogita K. Adlakha

“…MicroRNA-135 (MiR-135) exhibits brain-specific expression, and performs various functions such as neuronal morphology, neural induction, and synaptic function in the human brain. …”
Get full text

Housing Complexity Alters GFAP-Immunoreactive Astrocyte Morphology in the Rat Dentate Gyrus by Garrick Salois, Jeffrey S. Smith

“…In the dentate gyrus of the hippocampus, enriched environments evoke especially profound neural changes, including increases in the number of neurons and the number of dendritic spines. However, whether changes in astrocytes, a type of glia increasingly implicated in mediating neuroplasticity, are concurrent with these neural changes remains to be investigated. …”
Get full text

Long-Term Provision of Acidified Drinking Water Fails to Influence Autoimmune Diabetes and Encephalomyelitis by Sundararajan Jayaraman, Arathi Jayaraman

“…Interestingly, administration of complete Freund’s adjuvant alone or emulsified with a neuronal peptide to induce neurodegenerative disease during the prediabetic stage completely prevented the onset of diabetes regardless of the pH of the drinking water. …”
Get full text

Gastro-intestinal involvement in systemic sclerosis by Saurabh Kedia, Anuj Chhaparia, Pramod Garg

“…Vasculopathy, cellular and humoral immunity, and diffuse fibrosis are the principal pathogenetic mechanisms in SSc and begin with autoantibody-mediated neuronal damage followed by muscular damage and fibrosis. …”
Get full text

Rehabilitation with Poststroke Motor Recovery: A Review with a Focus on Neural Plasticity by Naoyuki Takeuchi, Shin-Ichi Izumi

“…Motor recovery after stroke is related to neural plasticity, which involves developing new neuronal interconnections, acquiring new functions, and compensating for impairment. …”
Get full text

Peripheral nerves adjacent to spinal cord injury could help restore sensory motor regeneration in complete paralysis patients by Mohammad Mousazadeh

“… Peripheral nerves adjacent to spinal cord injury could help restore sensory motor neurons regeneration Background and objectives: In people with spinal cord injury we hypothesize that peripheral nerves in the thoracic segment and accessory nerve and supra scapula nerve branches on the back of the patient can be sacrificed to use them to stimulate regeneration in spinal cord injury due to trauma. …”
Get full text

Long COVID-19: Psychological symptoms in COVID-19 and probiotics as an adjunct therapy by Angel Yun-Kuan Thye, Loh Teng-Hern Tan, Jodi Woan-Fei Law, Priyia Pusparajah, Vengadesh Letchumanan

“…Additionally, short-chain fatty acids (SCFAs) are crucial gut microbial metabolites with essential roles, including signaling along the microbiota-gut-brain (MGB) axis, maintaining blood-brain barrier’s (BBB) integrity, neuronal functions, neurotransmitters, and neurotrophic factors modulation. …”
Get full text

Pituitary adenylate cyclase-activating polypeptide plays a role in neuropsychiatric and substance use disorders: sex-specific perspective by Catherine E. Van Doorn, Mikala M. Zelows, Anel A. Jaramillo

“…We present literature linking PACAP to neuropsychiatric disorders, which demonstrate the intricate role of PACAP within neuronal signaling and pathways modulating addiction. …”
Get full text

The Adaptive Neuroplasticity Hypothesis of Behavioral Maintenance by Janey C. Peterson

“…We hypothesize that behavioral interventions that successfully promote physical activity may also enhance adaptive neuroplasticity and play a key role in the maintenance of physical activity through the development of new neuronal pathways that enhance functional ability in older adults. …”
Get full text

Treatment Tactics for Psychosis in Parkinson’s Disease: A Literature Review by Daiva Milmantienė

“…The loss of dopaminergic neurons and disturbances in their connections cause deficient signaling of dopamine circuits, which results in motor and non-motor symptoms. …”
Get full text

The Benefits and Detriments of Macrophages/Microglia in Models of Multiple Sclerosis by Khalil S. Rawji, V. Wee Yong

“…Such detriments include toxicity to neurons and oligodendrocyte precursor cells, release of proteases, release of inflammatory cytokines and free radicals, and recruitment and reactivation of T lymphocytes in the CNS. …”
Get full text

Decreasing alpha-synuclein aggregation on rotenone-induced adult Zebrafish as Parkinson’s Diseases model by ethanol extraction of Keluwih (Artocarpus camansi) leaves by Marisca Evalina Gondokesumo, Faisal Akhmal Muslikh, Ni Putu Diah Nopitasari, Putu Dea Angelita Putri

“…This progressive disease is characterized by the loss of neurons in the substantia nigra due to the presence of alpha-synuclein aggregates. …”
Get full text

Self‐Healing COCu‐Tac Hydrogel Enhances iNSCs Transplantation for Spinal Cord Injury by Promoting Mitophagy via the FKBP52/AKT Pathway by Zhenming Tian, Han‐Jian Hu, Chun Cheung Chan, Tian Hu, Chaoyang Cai, Hong Li, Limin Rong, Gang‐Biao Jiang, Bin Liu

“…This research reveals that the sustained release of tacrolimus enhances axonal growth and improves mitochondrial quality control in iNSCs and neurons. Further analysis shows that tacrolimus targets FKBP52 rather than FKBP51, enhancing mitophagy via the FKBP52/AKT pathway. …”
Get full text

Bidirectional relationship between sleep and depression by Shinnosuke Yasugaki, Hibiki Okamura, Ami Kaneko, Yu Hayashi

“…Recent animal studies support the bidirectional relation between depression and sleep, and animal models of depression are expected to be beneficial for the identification of neuronal circuits that connect stress, sleep, and depression. …”
Get full text

A Proposed Role for Lymphatic Supermicrosurgery in the Management of Alzheimer's Disease: A Primer for Reconstructive Microsurgeons by Joon Pio Hong, Wei F. Chen, Dung H. Nguyen, Qingping Xie

“…The relatively recent discovery of a novel lymphatic system within the brain meninges has spurred interest in how waste products generated by neurons and glial cells—including proteins associated with Alzheimer's disease (AD) pathology such as amyloid beta (Aβ) and tau—are disposed of. …”
Get full text

Implantable Ultrasound‐Powered MXene/PVA Hydrogel‐Based Generator for Treatment of Glioblastoma by Xiaoping Hu, Ziyi Qiu, Yilin Yang, Ting Xu, Kai Sheng, Weicheng Lu, Jingdun Xie, Bingzhe Xu

“…In this study, an implantable, modulus‐tunable, and ultrasound‐powered MXene/PVA hydrogel‐based tumor treatment device (UP‐MPH‐TTD), which generates specific electromagnetic alternating fields that disrupt the mitosis of cancer cells without adversely affecting normal neurons is developed. The MXene/PVA hydrogel is used to form a tumor treatment field due to its high biocompatibility, excellent flexibility, and high conductivity, which improves ultrasonic electrical conversion efficiency and significantly reduces the size of the equipment. …”
Get full text

Neuroprotection as a Therapeutic Target for Diabetic Retinopathy by Cristina Hernández, Massimo Dal Monte, Rafael Simó, Giovanni Casini

“…DR has long been regarded as a vascular disorder, although neuronal death and visual impairment appear before vascular lesions, suggesting an important role played by neurodegeneration in DR and the appropriateness of neuroprotective strategies. …”
Get full text

Secondary motor cortex tracks decision value during the learning of a non-instructed task by Elisabete Augusto, Vladimir Kouskoff, Nicolas Chenouard, Margaux Giraudet, Léa Peltier, Aron de Miranda, Alexy Louis, Lucille Alonso, Frédéric Gambino

“…We use in vivo microscopy and modeling to show that M2 neurons in male mice exhibit persistent activity-encoding decision values that predict action-selection probabilities. …”
Get full text