The Fractured Self: Exploring Selfhood in the Neuronovel The Echo Maker and the Neuromemoir Brain on Fire by Bonnie Cross

“…While the result of the connections of millions of neurons is a smooth and linear perception of the self and the world around us, neuronarratives can complicate this process by revealing the divisions and occasional contradictions that occur in the combination.…”
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Poor fixation stability does not account for motion perception deficits in amblyopia by Kimberly Meier, Simon Warner, Miriam Spering, Deborah Giaschi

“…It is possible that poor fixation stability during motion viewing interferes with the fidelity of the input to motion-sensitive neurons in visual cortex. To probe these mechanisms at a behavioral level, we assessed motion coherence thresholds in adults with amblyopia while measuring fixation stability. …”
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Autoimmune encephalitis: case reports of anti-NMDAR and anti-CASPR2 encephalitides and literature review by J. Kazlauskaitė, N. Giedraitienė, R. Masaitienė, A. Klimašauskienė

“…In clinical practice, neuronal antibodies remain the most significant diagnostic marker currently available. …”
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Regulation of Glial Cell Functions by PPAR-𝜸 Natural and Synthetic Agonists by Antonietta Bernardo, Luisa Minghetti

“…The pleiotropic effects of PPAR-𝛾 agonists are likely to be mediated by several mechanisms involving anti-inflammatory activities on peripheral immune cells (macrophages and lymphocytes), as well as direct effects on neural cells including cerebral vascular endothelial cells, neurons, and glia. In the present article, we will review the recent findings supporting a major role for PPAR-𝛾 agonists in controlling neuroinflammation and neurodegeneration through their activities on glial cells, with a particular emphasis on microglial cells as major macrophage population of the brain parenchyma and main actors in brain inflammation.…”
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Mitochondrial Stress Signalling: HTRA2 and Parkinson's Disease by Enrico Desideri, L. Miguel Martins

“…Mitochondria have a crucial role in supplying energy to the brain, and their deterioration can affect the function and viability of neurons, contributing to neurodegeneration. These organelles can sow the seeds of their own demise because they generate damaging oxygen-free radicals as a byproduct of their intrinsic physiological functions. …”
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Aetiology of Vertigo as Seen at the Federal Medical Center Lokoja, North Central Nigeria by Stephen Agbomhekhe Ogah

“…Bengin Paroxysmal Positional Vertigo (BPPV) 22(44%) was the commonest aetiology found followed by Meniere's disease 8(16%), trauma 7(14%) and Vestibular Neuronitis 5(10%) respectively. Keywords: Aetiology, vertigo, BPPV, Meniere's disease.…”
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Nanocarriers-Assisted Nose-to-Brain Delivery of Levodopa: Current Progress and Prospects by Mariya Dangova, Nadezhda Ivanova, Velichka Andonova

“…However, such advancement would be unthinkable without the current progress in nano-scaled drug carriers which are needed to ensure drug stability, mucosal retention and permeation, olfactory uptake, and harmlessness to the sensory neurons and respiratory cilia. This study aims to review the most significant results and achievements in the field of nano-particulate nose-to-brain delivery of L-DOPA.…”
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Understanding Muscle Dysfunction in Chronic Fatigue Syndrome by Gina Rutherford, Philip Manning, Julia L. Newton

“…Historically, there has been a tendency to draw psychological explanations for the origin of fatigue; however, this model is at odds with findings that fatigue and accompanying symptoms may be explained by central and peripheral pathophysiological mechanisms, including effects of the immune, oxidative, mitochondrial, and neuronal pathways. For example, patient descriptions of their fatigue regularly cite difficulty in maintaining muscle activity due to perceived lack of energy. …”
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Molecular and cellular characteristics of cerebrovascular cell types and their contribution to neurodegenerative diseases by Francisco J. Garcia, Myriam Heiman

“…We focus on human and mouse cerebrovasculature studies and discuss both origins and consequences of cerebrovascular dysfunction, emphasizing known cell type-specific vulnerabilities in neuronal and cerebrovascular cell populations. Lastly, we highlight how novel insights into cerebrovascular biology have impacted the development of modern therapeutic approaches and discuss outstanding questions in the field.…”
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The connecting brain in context: How adolescent plasticity supports learning and development by Amanda E. Baker, Adriana Galván, Andrew J. Fuligni

“…Puberty initiates significant neurobiological changes that amplify adolescents’ responsiveness to their environment, facilitating neural adaptation through processes like synaptic pruning, myelination, and neuronal reorganization. This heightened neuroplasticity, combined with their burgeoning social curiosity and appetite for risk, propels adolescents to explore diverse new environments and forge social bonds. …”
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Complexity of Deep Convolutional Neural Networks in Mobile Computing by Saad Naeem, Noreen Jamil, Habib Ullah Khan, Shah Nazir

“…Neural networks employ massive interconnection of simple computing units called neurons to compute the problems that are highly nonlinear and could not be hard coded into a program. …”
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Targeting Histone Deacetylases: A Novel Approach in Parkinson’s Disease by Sorabh Sharma, Rajeev Taliyan

“…The possible mechanisms assigned for these neuroprotective actions of HDAC inhibitors involve transcriptional activation of neuronal survival genes and maintenance of histone acetylation homeostasis, both of which have been shown to be dysregulated in PD. …”
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Lowering B-type natriuretic peptide levels and increasing cardiac function: the role of levosimendan in the treatment of heart failure by Jianfeng Meng, Ye Zuo

“…All patients received recombinant human neuronal natriuretic peptide (rhBNP) and the treatment group additionally received levosimendan. …”
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Reservoir Flood Forecasting Based on Long-Short-Term Memory Neural Network by LUO Zhaolin, ZHANG Bo, MENG Qingkui, CHEN Wufen

“…Accurate flood forecasting is one of the main means to well perform flood control and drainage,and the long-short-term memory neural network (LSTM) has a strong ability to fit time series relationships,which thus is very suitable for simulating and forecasting the complex time series process of basin runoff generation and confluence.To explore the applicability of LSTM in the field of reservoir flood forecasting,this paper established an LSTM model according to different forecast periods in the Baipenzhu Basin and compared it with Xinanjiang model.The LSTM model uses the rainfall and water level data in the basin as input and adopts the water levels of the reservoir at different forecast periods as output.The calibration period is five years,and the verification period is one year.The results show that LSTM has high forecast accuracy when the forecast period is 1~6 h,and the forecast accuracy is the highest when the forecast period is 1h,reaching 0.991.As the forecast period increases,the accuracy of the LSTM model gradually decreases,but its forecast accuracy is higher than that of Xinanjiang model.In addition,reflecting the complexity of the neural network,the prediction period and the number of neurons in the hidden layer will affect not only the forecast accuracy but also the training speed of the model.It is proven that the LSTM model has high forecast accuracy and is of guiding significance to reservoir flood forecasting.…”
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A Patient with Double-Negative VGKC, Peripheral Nerve Hyperexcitability, and Central Nervous System Symptoms: A Postinfectious Autoimmune Disease by Birte Eikeland

“…In the setting of anti-VGKC positivity, it seems likely that anti-VGKC contributed to the pathogenesis of the patient’s symptoms of nerve hyperexcitability and that the disease was caused by an acquired autoimmune effect on the neuronal kinetics of VGKC. It is still unknown whether or not there are unidentified extracellular molecular targets within the VGKC-complex, i.e., a novel surface antigen and a pathogenic antibody that can cause affected individuals to develop a peripheral nerve hyperexcitability syndrome. …”
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Object identity representation occurs early in the archerfish visual system by Svetlana Volotsky, Ronen Segev

“…We found that, although the optic tectum is an early stage of visual processing, a small population of neurons in this region contains information about the object category. …”
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Role of astrocytes connexins - pannexins in acute brain injury by Juan E. Tichauer, Maximiliano Rovegno

“…However, after acute brain injury, astrocytes can change their phenotype and modify the activity of both channels and hemichannels, which can result in the amplification of danger signals, increased mediators of inflammation, and neuronal death, contributing to the expansion of brain damage and neurological deterioration. …”
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Contributions of Matrix Metalloproteinases to Neural Plasticity, Habituation, Associative Learning and Drug Addiction by John W. Wright, Joseph W. Harding

“…., neural plasticity) by degrading cell adhesion molecules (CAMs) designed to provide stability to those extracellular matrix (ECM) proteins that form scaffolding supporting neurons and glia. It is presumed that while these ECM proteins are weakened, and/or detached, synaptic connections can form resulting in new neural pathways. …”
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Promotion of nitric oxide production: mechanisms, strategies, and possibilities by Marcos Gonzalez, Sarah Clayton, Eric Wauson, Daniel Christian, Quang-Kim Tran

“…NO can be produced by isoforms of NO synthases (NOS), including the neuronal (nNOS), inducible (iNOS), and endothelial isoforms (eNOS), and via the non-classical nitrate-nitrite-NO pathway. …”
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Mesenchymal Stem Cells: A Potential Therapeutic Approach for Amyotrophic Lateral Sclerosis? by Agnese Gugliandolo, Placido Bramanti, Emanuela Mazzon

“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the degeneration of both upper and lower motor neurons. Patients show both motor and extra-motor symptoms. …”
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