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1741
Follow-Up and Risk Assessment in Patients with Myocardial Infarction Using Artificial Neural Networks
Published 2017-01-01“…Artificial neural networks (ANNs) are machine learning technique, inspired by the principles found in biological neurons. This technique has been used for prediction and classification problems in many areas of medical signal processing. …”
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1742
Neurobiological Mechanism of Acupuncture for Relieving Visceral Pain of Gastrointestinal Origin
Published 2017-01-01“…The generation of pain involves a series of processes, including energy transduction of stimulatory signals in the sensory nerve endings (signal transduction), subsequent conduction in primary afferent nerve fibers of dorsal root ganglia, and transmission to spinal dorsal horn neurons, the ascending transmission of sensory signals in the central nervous system, and the processing of sensory signals in the cerebral cortex. …”
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1743
An intein-split transactivator for intersectional neural imaging and optogenetic manipulation
Published 2022-06-01“…The IBIST-based Ca2+ imaging showed that the IBIST can intersect five features and that hippocampal neurons tune differently to distinct emotional stimuli depending on the pattern of projection targets. …”
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1744
SNP Analysis of the SOD1 gene involved in Amyotrophic Lateral Sclerosis (ALS)
Published 2025-12-01“…ALS is a rare neurodegenerative disease causing the loss of motor neurons in the brain and spinal cord. Mutations in over forty genes, particularly the Superoxide Dismutase 1 (SOD1) gene, are linked to ALS. …”
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1745
The underappreciated contribution of Oskar Fischer to the knowledge of Frontotemporal Lobar Degeneration
Published 2025-02-01“…Oskar Fischer significantly advanced this field by detailing the histopathological features of these conditions, such as the ‘spongiform cortical wasting’, and identifying characteristic neuronal changes such as the ‘ballooned cells’. Fischer’s contributions, alongside those of contemporaries like Alois Alzheimer, laid the foundation for understanding FTLD histopathology. …”
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1746
Prefrontal cortex synchronization with the hippocampus and parietal cortex is strategy-dependent during spatial learning
Published 2025-01-01“…When mice used spatial strategies specifically in searching stage, hippocampal and parietal oscillations synchronized gamma oscillations (60-100 Hz) and neuronal firing in the mPFC. This coincided with an increase in the incidence of gamma and task-stage-related changes in firing patterns in the mPFC. …”
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1747
Application of Low Intensity Ultrasound in the Treatment of Alzheimer’s Disease
Published 2025-03-01“…For pathological research, the development of low-intensity ultrasound (LIUS) provides another idea for the mechanism of AD treatment, which can better treat AD, regulate various factors specifically, and effectively treat AD by stimulating synapses and improving neurons. Based on this research background, this paper summarizes the role of AD biomarkers TAU protein, phosphorylated tau and amyloid protein in the occurrence and development of AD and the mechanism of pathological changes in the treatment of AD by low-intensity ultrasound, aiming to provide new insights into clarifying the pathological changes of AD biomarkers and the mechanism of LIUS in the treatment of AD. …”
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1748
Chronic Synthetic Marijuana Use: A Case of First-Onset Seizures as a Withdrawal Symptom
Published 2022-04-01“…Some early results in the literature also show that SM use can lead to functional and structural neuronal changes. This manuscript discusses a case of a first on-set seizure as a possible withdrawal symptom in chronic SM use.…”
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1749
Genome sequence of Streptomyces antioxidans MUSC 164T isolated from mangrove forest
Published 2018-04-01“…After 31 rounds of in vitro screening using human neuronal cell line (i.e. SH-SY5Y), the extract of 32 MUSC 164T was found to possess significant neuroprotective effect against hydrogen 33 peroxide[13]. …”
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1750
Adjudicating between face-coding models with individual-face fMRI responses.
Published 2017-07-01“…Accounting for the data required the inclusion of a measurement-level population averaging mechanism that approximates how fMRI voxels locally average distinct neuronal tunings. Our study demonstrates the importance of comparing multiple models and of modeling the measurement process in computational neuroimaging.…”
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1751
MicroRNAs in the Neural Retina
Published 2014-01-01“…The retina, as a part of the central nervous system, is a well-established model for unraveling the molecular mechanisms underlying neuronal and glial functions. Numerous recent efforts have been made towards identification of miRNAs and their inferred roles in the visual pathway. …”
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1752
Neuropsychiatric symptoms in Alzheimer’s disease
Published 2024-02-01“…Alzheimer’s disease is one of the most common neurodegenerative diseases among older people that manifests as deterioration of cognitive functions, impaired daily activities, and progressive degeneration of cerebral cortex neurons. Even up to 90% of Alzheimer’s patients develop neuropsychiatric symptoms at different stages of the disease. …”
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1753
Multiple Functions of Phosphoinositide-3 Kinase Enhancer (PIKE)
Published 2010-01-01“…In the past 10 years, we have characterized a novel class of GTPases called phosphoinositide-3 kinase enhancer (PIKE) that interacts with PI3K/Akt. In neurons, PIKE is involved in the protective mechanisms against neuroexcitotoxic insults by linking various receptors, such as mGluR1 and Unc5H2, to the PI3K cascade. …”
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1754
The crucial role of 5hmC in neuroprotection and repair after cerebrovascular injury
Published 2024-07-01“…This review consolidates current research on the multifaceted role of 5-hydroxymethylcytosine (5hmC) in regulating molecular and cellular processes vital for neuronal survival and regeneration after cerebrovascular injury. …”
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1755
The Neuropathology of Autism
Published 2012-01-01“…Abnormalities include cytoarchitectonic laminar differences, excess white matter neurons, decreased numbers of GABAergic cerebellar Purkinje cells, and other events that can be traced developmentally and cause anomalies in circuitry. …”
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1756
When the Stomach Pain Is Literally “In Your Head”
Published 2024-02-01“…Temporal lobe epilepsy often has no clear cause, although it may be associated with diseases such as temporal lobe sclerosis, dysembryoplastic neuroepithelial tumours, and other benign tumours, as well as arterio-venous malformations, gliomas, defects in neuronal migration, or lesions of the cortex caused by encephalitis. …”
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1757
Myelin ensheathment and drug responses of oligodendrocytes are modulated by stiffness of artificial axons.
Published 2025-01-01“…Myelination is a key biological process wherein glial cells such as oligodendrocytes wrap myelin around neuronal axons, forming an insulative sheath that accelerates signal propagation down the axon. …”
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1758
Improvement of in Vivo Quantification of [I]-Iodobenzovesamicol in Single-Photon Emission Computed Tomography/Computed Tomography Using Anatomic Image to Brain Atlas Nonrigid Regis...
Published 2013-07-01“…For patients suffering from neurogenerative disease, this study demonstrates the importance and relevance of MRI to atlas registration in quantification of neuronal integrity. In this context, in comparison with rigid registrations, an elastic model–based registration provides the best relocation of the brain structures to the atlas for accurately quantifying cholinergic neurotransmission.…”
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1759
Malware detection approach based on improved SOINN
Published 2019-12-01“…To deal with the problems of dynamic update of detection model and high computation costs in malware detection model based on batch learning,a novel malware detection approach is proposed by combing SOINN and supervised classifiers,to reduce computation costs and enable the detection model to update dynamically with the assistance of SOINN′s incremental learning characteristic.Firstly,the improved SOINN was given.According to the whole alignment algorithm,search the adjusted weights of neurons under all input sequences in the learning cycle and then calculate the average value of all adjusted weights as the final result,to avoid SOINN′s stability under different input sequences and representativeness of original data,therefore improve malware detection accuracy.Then a data preprocessing algorithm was proposed based on nonnegative matrix factor and Z-score normalization to transfer the malware behavior feature vector from high dimension and high order to low dimension and low order,to speed up and avoid overfitting and further improve detection accuracy.The results of experiments show that proposed approach supports dynamic updating of detection model and has a significantly higher accuracy of detecting unknown new samples and lower computation costs than tradition methods.…”
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1760
Acquisition of similar properties by filters in the same stream of a multistream convolutional neural network
Published 2025-01-01“…In the visual cortex of primates, adjacent neurons often respond to the same visual submodality, such as color or orientation, and have a similar preferred orientation or preferred color. …”
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