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1721
Platelets tune fear memory in mice
Published 2025-02-01“…Both NK cells and platelet depletion reduce the activation of hippocampal inhibitory neurons and increase the long-term potentiation of synaptic transmission. …”
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1722
Cell Transplantation for Spinal Cord Injury: Tumorigenicity of Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cells
Published 2018-01-01“…Neural stem/progenitor cell (NS/PC) transplantation derived from fetal tissues or embryonic stem cells (ESCs) has demonstrated therapeutic effects via replacement of lost neurons and severed axons and creation of permissive microenvironment to promote repair of spinal cord and axon regeneration but causes ethnical concerns and immunological rejections as well. …”
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1723
Development of a Cell-Based Functional Assay for the Detection of Clostridium botulinum Neurotoxin Types A and E
Published 2013-01-01“…Here, we describe a cell-based assay utilizing a fluorescence reporter construct expressed in a neuronal cell model to study toxin activity in situ. …”
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1724
Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity
Published 2025-01-01“…By integrating genomic insights from genome-wide association studies with a comprehensive single-cell transcriptomic atlas of the adult human brain, we prioritized specific neuronal clusters significantly enriched for the SNP-heritabilities for schizophrenia, bipolar disorder, and major depressive disorder along with intelligence, education, and neuroticism. …”
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1725
Neuroprotection and Stroke Rehabilitation: Modulation and Enhancement of Recovery
Published 2006-01-01“…This review discusses mechanisms of neuronal injury after brain ischemia and the attempts to study neuroprotection options based on such mechanisms. …”
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1726
Effect of Centella asiatica Leaf Extract on the Dietary Supplementation in Transgenic Drosophila Model of Parkinson’s Disease
Published 2014-01-01“…The role of Centella asiatica L. leaf extract was studied on the transgenic Drosophila model flies expressing normal human alpha synuclein (h-αS) in the neurons. The leaf extract was prepared in acetone and was subjected to GC-MS analysis. …”
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1727
Fault Diagnosis of High-Speed Train Bogie Based on Synchrony Group Convolutions
Published 2019-01-01“…The proposed method is able to gather signals with similar patterns and process these channels with specific groups of neurons while simultaneously assigning signals with significant difference to different groups. …”
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1728
Friends or Foes: Matrix Metalloproteinases and Their Multifaceted Roles in Neurodegenerative Diseases
Published 2015-01-01“…Neurodegeneration is a chronic progressive loss of neuronal cells leading to deterioration of central nervous system (CNS) functionality. …”
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1729
Nucleolar PARP-1 Expression Is Decreased in Alzheimer’s Disease: Consequences for Epigenetic Regulation of rDNA and Cognition
Published 2016-01-01“…Nucleolar PARP-1 staining ranged from dispersed and less intense to entirely absent in AD compared to the distinct nucleolar localization in hippocampal pyramidal neurons in controls. In cases of AD, the percentage of hippocampal pyramidal cells with nucleoli that were positive for both PARP-1 and the nucleolar marker fibrillarin was significantly lower than in controls. …”
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1730
Role of neuroimmunomodulation by vagus nerve stimulation in rheumatoid arthritis: Are we heading towards a drug-free era?
Published 2020-01-01“…This review discusses the multifactorial and multidimensional interactions between neurons and immune cells, the mechanisms of the nervous system which are responsible for the regulation of inflammation, the impact of cholinergic pathways on inflammation, and the evidence supporting the role of various bioelectronic devices in vagus nerve stimulation.…”
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1731
Luminosity Distance Reconstruction using an Ensemble of Neural Networks
Published 2024-07-01“…Each network in the ensemble consists of various numbers of layers and neurons. Since the neural network can easily provide a reconstruction with a small value of $\chi2$, it is possible to find a reconstruction with $\chi^2$ smaller than the standard $\Lambda$CDM. …”
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1732
Impaired GABA Neural Circuits Are Critical for Fragile X Syndrome
Published 2018-01-01“…Fragile X syndrome (FXS) is an inheritable neuropsychological disease caused by silence of the fmr1 gene and the deficiency of Fragile X mental retardation protein (FMRP). Patients present neuronal alterations that lead to severe intellectual disability and altered sleep rhythms. …”
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1733
Cyclin-Dependent Kinase 5/p35/p39: A Novel and Imminent Therapeutic Target for Diabetes Mellitus
Published 2011-01-01“…CDK5 is a serine/threonine protein kinase, which forms active complexes with p35 or p39 found principally in neurons and in pancreatic β cells. Pieces of evidence from recent studies recommend the vital role of CDK5 in physiological functions in nonneuronal cells such as glucose-stimulated insulin secretion in pancreatic cells. …”
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1734
Clinical Interaction between Brain and Kidney in Small Vessel Disease
Published 2011-01-01“…These results indicate that CKD markers may be helpful to predict the future risk of neuronal disease.…”
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1735
MEPFeatX—automated feature extraction of motor-evoked potentials in transcranial magnetic stimulation
Published 2025-01-01“…Motor evoked potentials (MEPs) are an important measure in transcranial magnetic stimulation (TMS) when assessing neuronal excitability in clinical diagnostics related to motor function, as well as in neuroscience research. …”
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1736
Autism common variants associated with white matter alterations at birth: cross-sectional fixel-based analyses of 221 European term-born neonates from the developing human connecto...
Published 2025-02-01“…Subsequent exploratory enrichment analysis revealed that the autism risk single nucleotide polymorphisms most associated with the imaging phenotype may have roles in neuronal cellular components. Together, these findings suggest a possible link between autism common variants and early WM development.…”
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1737
Noncoding variants and sulcal patterns in congenital heart disease: Machine learning to predict functional impact
Published 2025-02-01“…Genes predicted to be regulated by these ncDNVs were enriched for functions related to neuronal development. This highlights the potential of deep learning models to generate hypotheses about the role of noncoding variants in brain development.…”
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1738
Expression of Constitutive Nitric Oxide Synthase Isoforms in Varicose Vein Wall; Preliminary Results
Published 2011-01-01“…From 3 known NOS isoforms the two are constitutional: eNOS (endothelial NOS) and nNOS (neuronal NOS). 10 varicose and 10 control vein samples were processed by standard light microscopy and immuno-histochemica techniques using rabbit polyclonal antibodies against eNOS and nNOS. …”
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1739
Central auditory processing in epileptic children
Published 2025-02-01“…Abstract Background Epilepsy is characterized by the transient occurrence of signs or symptoms due to hypersynchronous or excessive neuronal activity. Seizures caused by epilepsy during brain development can hinder the normal growth and functioning of the brain, which may negatively impact the acquisition of cognitive skills that are crucial for the learning process. …”
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1740
Evaluador inteligente de daño fenológico en la planta de trigo
Published 2019-01-01“…Considerando la importancia de este cereal como alimento de la dieta básica de los seres humanos, se propone una nueva forma de evaluación del cultivo que permita pronosticar el daño probable por etapa fenológica por medio de una red neuronal artificial entrenada con datos históricos del comportamiento climático global e impacto fenológico. …”
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