Procesamiento de bases de datos escolares por medio de redes neuronales artificiales by Brenda Miranda García, Víctor Manuel González Bárcenas, Adriana Reyes Nava, Roberto Alejo Eleuterio, Eréndira Rendón Lara

“…En este artículo se estudia este problema con el uso de tres modelos de red neuronal. Los resultados evidencian la capacidad de estos modelos para clasificar con un porcentaje de acierto superior a 95% las tendencias en los estudiantes utilizando principalmente datos cualitativos.…”
Get full text

Effects of Various Flavonoids on the α-Synuclein Fibrillation Process by Xiaoyun Meng, Larissa A. Munishkina, Anthony L. Fink, Vladimir N. Uversky

“…α-Synuclein aggregation and fibrillation are closely associated with the formation of Lewy bodies in neurons and are implicated in the causative pathogenesis of Parkinson's disease and other synucleinopathies. …”
Get full text

Forecast of Chaotic Series in a Horizon Superior to the Inverse of the Maximum Lyapunov Exponent by Miguel Alfaro, Guillermo Fuertes, Manuel Vargas, Juan Sepúlveda, Matias Veloso-Poblete

“…The delay time and the global dimension are employed as parameters in the models of forecast of artificial neuronal networks (ANN) and support vector machine (SVM). …”
Get full text

Formulated citrus peel extract gold lotion improves cognitive and functional recovery from traumatic brain injury (TBI) in rats by Cheng Guang, Yue Zhiwei, Wang Liwen, Miyauchi Yutaka, Suzawa Michiko, Li Shiming, Ho Chi‐Tang, Zhao Hui, Chen Naiyao

“…The mechanisms probably due to that GL could not only reduce the associated damage markers including GFAP, OX-42, TNF-α, COX-2, NF-κB and TLR4 but also promote the expression of VEGF which is responsible for protecting neuronal cells in the injury area. These findings revealed that GL could be a promising preparation for TBI prevention.…”
Get full text

Therapeutic Potentials of Synapses after Traumatic Brain Injury: A Comprehensive Review by Zunjia Wen, Dong Li, Meifen Shen, Gang Chen

“…Second, we briefly describe several key synaptic proteins involved in neuroplasticity, which may be novel neuronal targets for specific intervention. Third, we address therapeutic interventions in association with synapses after TBI. …”
Get full text

The mitochondria as a potential therapeutic target in cerebral I/R injury by Susu Fang, Susu Fang, Wenzhou Huang, Wenzhou Huang, Xinhui Qu, Xinhui Qu, Wen Chai

“…However, reperfusion can induce neuronal death, known as cerebral reperfusion injury, for which effective therapies are lacking. …”
Get full text

Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease by Géraldine Gelders, Veerle Baekelandt, Anke Van der Perren

“…Nevertheless, several questions remain unanswered regarding the role of misfolded protein aggregates and the cause of neuronal cell death. Recently, it has been postulated that neuroinflammatory processes might play a crucial role in the pathogenesis of PD. …”
Get full text

The Roles of Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 in Cancer and Cancer Stem Cells by Junguo Cao, Qingchun Mu, Haiyan Huang

“…IGF2BP2 represents the least understood member of this family of RBPs; however, it has been reported to participate in a wide range of physiological processes, such as embryonic development, neuronal differentiation, and metabolism. Its dysregulation is associated with insulin resistance, diabetes, and carcinogenesis and may potentially be a powerful biomarker and candidate target for relevant diseases. …”
Get full text

Investigating the impact of microbiome-changing interventions on food decision-making: MIFOOD study protocol by Meghedi Vartanian, Konrad Jakob Endres, Yee Teng Lee, Silke Friedrich, Marie-Theres Meemken, Imke Schamarek, Kerstin Rohde-Zimmermann, Robin Schürfeld, Lina Eisenberg, Anja Hilbert, Frauke Beyer, Michael Stumvoll, Julia Sacher, Arno Villringer, Julia F. Christensen, A. Veronica Witte

“…However, causal evidence on how these “bottom-up” and “top-down” processes affect food decision-making and neuronal correlates in humans is still scarce. In addition, microbiome, and gut-brain-axis-related mediating mechanisms remain unclear. …”
Get full text

Structural basis of a microbial trimethylamine transporter by Chao Gao, Hai-Tao Ding, Kang Li, Hai-Yan Cao, Ning Wang, Zeng-Tian Gu, Qing Wang, Mei-Ling Sun, Xiu-Lan Chen, Yin Chen, Yu-Zhong Zhang, Hui-Hui Fu, Chun-Yang Li

“…While the role of TMA in promoting cardiovascular diseases and depolarizing olfactory sensory neurons in humans has only recently been explored, many microbes are well known for their ability to utilize TMA as a carbon, nitrogen, and energy source. …”
Get full text

Spinally targeted paired associative stimulation with high-frequency peripheral component induces spinal level plasticity in healthy subjects by Anna Nätkynmäki, Leena Lauronen, Piia Haakana, Erika Kirveskari, Janne Avela, Anastasia Shulga

“…We sought to determine if the TMS-induced orthodromic activation in upper motor neurons and PNS-induced antidromic activation in lower motor neurons arriving simultaneously to the intervening synapses at the spinal cord level can be shown to induce acute changes at the targeted location, unlike an otherwise identical but cortically targeted equivalent. …”
Get full text

CEST imaging combined with 1H-MRS reveal the neuroprotective effects of riluzole by improving neurotransmitter imbalances in Alzheimer’s disease mice by Yuanyu Shen, Xiaolei Zhang, Siqi Liu, Lijing Xin, Wentao Xuan, Caiyu Zhuang, Yue Chen, Beibei Chen, Xinhui Zheng, Renhua Wu, Yan Lin

“…At the study endpoint, immunohistochemistry, Nissl staining, and Western blot were used to evaluate the brain pathology, neuronal survival, and protein expression. Results GluCEST, GABACEST and 1H-MRS consistently revealed higher levels of Glu and GABA in the brain of riluzole-treated AD mice compared to untreated controls, which were associated with improvements in spatial learning and memory. …”
Get full text

OBSERVATION OF THE NORMAL DEVELOPMENTAL PATTERN OF FETAL CEREBRAL SULCI BETWEEN 18 TO 32 WEEKS OF GESTATIONAL AGE BY USING ULTRASONOGRAPHY - A CORRELATIONAL STUDY BETWEEN TWO MATER... by Sujith Kumar Reddy Madithati, Sai Shankar Mankuzhy Gopalakrishnan, Santosh Chandrasekhar, Jenikar Paulraj, Archana Bala, Geeta Shankar

“…Lissencephaly, is a condition with "smooth brain," with the absence of normal convolutions (folds) in the cerebral cortex. Neuronal migration disorders result when the post mitotic neurons fail to migrate from the ventricular zone to the cortical plate, resulting in a wide spectrum of cortical malformations. …”
Get full text

Control of Linear-Threshold Brain Networks via Reservoir Computing by Michael McCreesh, Jorge Cortes

“…We illustrate the versatility of this setup in two applications: selective recruitment and inhibition of neuronal populations for goal-driven selective attention, and network intervention for the prevention of epileptic seizures.…”
Get full text

Feline Neural Progenitor Cells I: Long-Term Expansion under Defined Culture Conditions by Jing Yang, Jinmei Wang, Ping Gu, X. Joann You, Henry Klassen

“…The Ultraculture-based cultures expressed lower levels of progenitor and lineage-associated markers under proliferation conditions but retained multipotency as evidenced by the ability to differentiate into neurons and glia following growth factor removal in the presence of FBS. …”
Get full text

Modeling sacsin depletion in Danio Rerio offers new insight on retinal defects in ARSACS by Valentina Naef, Devid Damiani, Rosario Licitra, Maria Marchese, Stefania Della Vecchia, Matteo Baggiani, Letizia Brogi, Daniele Galatolo, Silvia Landi, Filippo Maria Santorelli

“…While two murine models replicate the phenotypic and neuronal features observed in patients, no retinal phenotype has been described so far. …”
Get full text

Investigating the influence of monosodium L-glutamate on brain responses via scalp-electroencephalogram (scalp-EEG) by Ben Wu, Xirui Zhou, Imre Blank, Yuan Liu

“…As the relevance between left and right brain neurons when transmitting electrical signals of umami taste is unknown, the aim of this work was to investigate responsive regions of the brain to the umami tastant monosodium glutamate (MSG) by using scalp-electroencephalogram (EEG) to identify the most responsive brain regions to MSG. …”
Get full text

Using Electrocardiogram Signal Features and Heart Rate Variability to Predict Epileptic Attacks by Ying Jiang, Yuan Feng, Danni Lu, Lin Yang, Qun Zhang, Haiyan Yang, Ning Li

“…Since the increase in neuronal activity during an epileptic attack affects the voluntary nervous system, and the voluntary nervous system also affects the heart rate variability, it can be concluded that seizures can be predicted by monitoring heart rate variability. …”
Get full text

Combination Treatment of C16 Peptide and Angiopoietin-1 Alleviates Neuromyelitis Optica in an Experimental Model by Yuanyuan Zhang, Kewei Tian, Hong Jiang, Beibei Wang, Shu Han

“…Moreover, NMO may cause secondary complement-dependent cytotoxicity (CDC), leading to oligodendrocyte and neuronal damage. In this study, a rodent NMO model, showing typical NMO pathogenesis, was induced with NMO-IgG from patient serum and human complement. …”
Get full text

Optimizing Cutting Conditions and Prediction of Surface Roughness in Face Milling of AZ61 Using Regression Analysis and Artificial Neural Network by Nabeel H. Alharthi, Sedat Bingol, Adel T. Abbas, Adham E. Ragab, Ehab A. El-Danaf, Hamad F. Alharbi

“…Five models of neural network were developed and the model that showed best fit with experimental results was with 6 neurons in the hidden layer. Regression analysis was also used to build a mathematical model representing the surface roughness as a function of the process parameters. …”
Get full text