Histone Deacetylase Inhibitors in Cell Pluripotency, Differentiation, and Reprogramming by Androniki Kretsovali, Christiana Hadjimichael, Nikolaos Charmpilas

“…In addition, they can promote directed differentiation of embryonic and tissue-specific stem cells along the neuronal, cardiomyocytic, and hepatic lineages. They have been used to facilitate embryo development following somatic cell nuclear transfer and induced pluripotent stem cell derivation by ectopic expression of pluripotency factors. …”
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Recurrences Reveal Shared Causal Drivers of Complex Time Series by William Gilpin

“…Unmeasured causal forces influence diverse experimental time series, such as the transcription factors that regulate genes or the descending neurons that steer motor circuits. Combining the theory of skew-product dynamical systems with topological data analysis, we show that simultaneous recurrence events across multiple time series reveal the structure of their shared unobserved driving signal. …”
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Chronic pain in a family doctor practice – meaning, assessment, and therapeutic options by Dominika Prokop, Mikołaj Borek, Jan Baran, Dawid Rowiński, Oliwia Sikora, Katarzyna Chamera-Cyrek, Aneta Podczerwińska, Clara Kuzminski

“…Appropriately tailored therapeutic management is crucial because insufficient pain relief negatively affects the central nervous system, potentially leading to behavioural changes, emotional and psychological disorders, cognitive dysfunctions, abnormalities in cerebral blood flow, and a decrease in the number of neurons.…”
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COMPLEX SYMBOL "MIND" AND THE EPISTEMOLOGICAL RELATIVISM by Gintautas Mažeikis

“…There are short interpretations of various types of symbol "Mind": "the first cause of movement", "basis of being", "force of salvation", "strenght of harmonizing of cosmos", "creative power of form of thinking", "basis of structure of Ego", "product of connections of neurones", "expression of social and natural relations". …”
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Semblantes teóricos de Neuroartes: una vía hacia la salud sociovital by Myriam García Piedras

“…En este contexto, el arte y la salud se correlacionan a la manera de un binomio, y el arte conduce al despertar neuronal y expansión de los correlatos de la conciencia fortificando la salud individual y sociovital al generar las condiciones en la construcción y transformación de mundos más justos, inclusivos y solidarios.…”
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White Matter Injury in Central Nervous System Disorders by Zheng L, Wang X, Li P, Hao Y, Zhang H, Chen H, Zheng Z

“…Diseases of the CNS cause not only gray matter damage, which is primarily characterized by the loss of neurons, but also white matter damage. However, most previous studies have focused on grey matter injury (GMI), with fewer studies on white matter injury (WMI). …”
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A Photothermal Modelling Approach for Micro-LED Arrays in Wireless Optogenetics by Yanping Ji, Chuanzhen Liu, Jiawei Li, Wensi Wang, Mengyi Zheng

“…This type of light modulation enables effective stimulation of neurons. However, as optogenetics moves towards clinical trials, combinatorial photostimulation based on arrays of LED light sources has emerged. …”
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The N17 domain of huntingtin as a multifaceted player in Huntington’s disease by Hyunju Cho

“…Huntington’s disease (HD) is primarily caused by the aberrant aggregation of the N-terminal exon 1 fragment of mutant huntingtin protein (mHttex1) with expanded polyglutamine (polyQ) repeats in neurons. The first 17 amino acids of the N-terminus of Httex1 (N17 domain) immediately preceding the polyQ repeat domain are evolutionarily conserved across vertebrates and play multifaceted roles in the pathogenesis of HD. …”
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Hypothalamus-pituitary-adrenal and gut-brain axes in biological interaction pathway of the depression by Amanda Gollo Bertollo, Camila Ferreira Santos, Margarete Dulce Bagatini, Zuleide Maria Ignácio

“…The HPA axis regulates the body's stress response, and chronic stress can lead to overactivation of the HPA axis, resulting in elevated cortisol levels that contribute to neuronal damage, particularly in regions such as the hippocampus and prefrontal cortex, both of which are involved in mood regulation and mental disorders. …”
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The therapeutic agents that target ATP-sensitive potassium channels by Rubaiy Hussein N.

“…Also, KATP channels are involved in the protection against neuronal seizures and ischaemic stress in the heart, brain and in the regulation of vascular smooth muscle tone. …”
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Family case of cardiac achalasia by Yu. V. Yevsyutina, A. S. Trukhmanov, V. T. Ivashkin

“…Cardiac achalasia is idiopathic disease, caused by inflammation and degeneration of myenteric plexus resulting in loss of postganglionic inhibitory neurons, essential for relaxation of the lower esophageal sphincter and peristaltic contractions of the esophagus. …”
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Management of Ocular Diseases Using Lutein and Zeaxanthin: What Have We Learned from Experimental Animal Studies? by Chunyan Xue, Richard Rosen, Adrienne Jordan, Dan-Ning Hu

“…In these animal models, lutein and zeaxanthin have been reported to have beneficial effects in protecting ocular tissues and cells (especially the retinal neurons) against damage caused by different etiological factors. …”
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Comparative analysis of pediatric SHH medulloblastoma DAOY spheres and adherent monolayers: implications for medulloblastoma research by Jana Klementová, Šárka Jarošová, Irina Danilová, Markéta Farníková, Josef Novotný, Marie Davídková, Martina Zíková

“…Our findings demonstrate that DAOY spheres express markers for both neural stem cells, such as CD133 (PROM1), and differentiated neurons, exemplified by MAP2. Additionally, our investigation revealed that spheres-derived cells exhibit heightened resistance to ionizing radiation compared to adherent cells. …”
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EVALUATION OF THE THERAPEUTIC EFFECTS OF SALVIA ROSMARINUS ESSENTIAL OIL ON NERVOUS SYSTEM DISORDERS by Malina Mihaela Visternicu, Viorica Rarinca, Vasile Burlui, Alin Ciobica

“…Preclinical and clinical research suggests that rosemary extracts, through their active compounds, may enhance cognitive function, protect neurons from oxidative stress, and modulate neurotransmitters involved in cognitive and emotional processes. …”
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Pancreatic organogenesis mapped through space and time by Marissa A. Scavuzzo, Wojciech J. Szlachcic, Matthew C. Hill, Natalia M. Ziojla, Jessica Teaw, Jeffrey C. Carlson, Jonathan Tiessen, Jolanta Chmielowiec, James F. Martin, Malgorzata Borowiak

“…Signals from the mesenchyme, neurons, and endothelial cells instruct epithelial cell differentiation during pancreatic development. …”
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Crocetin Alleviates Inflammation in MPTP-Induced Parkinson’s Disease Models through Improving Mitochondrial Functions by Na Dong, Zhong Dong, Ying Chen, Xiaosu Gu

“…Our results showed that crocetin treatment attenuates MPTP-induced motor deficits and protects dopaminergic neurons. Both in vivo and in vitro experiments demonstrated that crocetin treatment decreased the expression of inflammatory associated genes and inflammatory cytokines. …”
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Development of the inner ear and regeneration of hair cells after hearing impairment by Xin Bing, Chengcheng Liu, Xue Cao, Chengzhilin Li, Xiaochen Gao, Fangyuan Zhu, Xinhao Wu, Na Guo, Houyang Hu, Ming Xia, Miaoqing Zhao

“…It is mainly caused by the damage of inner ear hair cells (HCs) or the degeneration of spiral ganglion neurons. In mammals, cochlear HCs cannot regenerate naturally after injury, leading to irreversible hearing loss. …”
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Transmembrane voltage-gated nanopores controlled by electrically tunable in-pore chemistry by Makusu Tsutsui, Wei-Lun Hsu, Chien Hsu, Denis Garoli, Shukun Weng, Hirofumi Daiguji, Tomoji Kawai

“…Abstract Gating is a fundamental process in ion channels configured to open and close in response to specific stimuli such as voltage across cell membranes thereby enabling the excitability of neurons. Here we report on voltage-gated solid-state nanopores by electrically tunable chemical reactions. …”
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Probiotics alleviate painful diabetic neuropathy by modulating the microbiota–gut–nerve axis in rats by Ye Jiang, Jing Yang, Min Wei, Jiayin Shou, Shixiong Shen, Zhuoying Yu, Zixian Zhang, Jie Cai, Yanhan Lyu, Dongsheng Yang, Yongzheng Han, Jinpiao Zhu, Zhigang Liu, Daqing Ma, Guo-gang Xing, Min Li

“…Supplementation with multiple probiotics for 12 weeks alleviated pain, reversed nerve fiber lesions, and restored neuronal hyperexcitability. Probiotics administration effectively attenuated intestinal barrier impairment, reduced serum lipopolysaccharide and proinflammatory cytokines, and mitigated disruptions in the blood-nerve barrier. …”
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The Citron homology domain of MAP4Ks improves outcomes of traumatic brain injury by Xiaoling Zhong, Wenjiao Tai, Meng-Lu Liu, Shuaipeng Ma, Tianjin Shen, Yuhua Zou, Chun-Li Zhang

“…The mitogen-activated protein kinase kinase kinase kinases (MAP4Ks) signaling pathway plays a pivotal role in axonal regrowth and neuronal degeneration following insults. Whether targeting this pathway is beneficial to brain injury remains unclear. …”
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