-
1261
Circular RNA circ-Olfm1 induces progression of Alzheimer’s disease by regulating FOXO3a
Published 2025-01-01“…Western blotting showed that the addition of Aβ42 significantly increased the expression of AMPK and FOXO3a in the neuronal cells (P<0.01). And silencing circ-Olfm1 led to decreased expression of AMPK and FOXO3a in neuronal cells+Aβ42 (P<0.01). …”
Get full text
Article -
1262
Neuropathology and Neurochemistry of Nonmotor Symptoms in Parkinson's Disease
Published 2011-01-01“…Although there is a close relation between motor symptoms and the presence of Lewy bodies (LBs) and neurites filled with abnormal 𝛼-synuclein, other neurological alterations are independent of the amount of 𝛼-synuclein inclusions in neurons and neurites, thereby indicating that different mechanisms probably converge in the degenerative process. …”
Get full text
Article -
1263
Emerging Roles of BAI Adhesion-GPCRs in Synapse Development and Plasticity
Published 2016-01-01“…Synapses mediate communication between neurons and enable the brain to change in response to experience, which is essential for learning and memory. …”
Get full text
Article -
1264
Skin Matters: Identifying Pain Mechanisms and Predicting Treatment Outcomes
Published 2013-01-01“…Cutaneous sensory neurons expressing nociceptive receptors such as transient receptor potential vanilloid 1 channels and voltage-gated sodium channels are critical for pain transmission. …”
Get full text
Article -
1265
A Hybrid Wavelet Transform Based Short-Term Wind Speed Forecasting Approach
Published 2014-01-01“…In order to find the optimal network architecture, the partial autocorrelation function is adopted to determine the number of neurons in the input layer, and an experimental simulation is made to determine the number of neurons within each hidden layer in the modeling process of TNN. …”
Get full text
Article -
1266
Mobile Phone Radiation Effects on Brain with Reference to the Protective Role of Moringa oleifera: Sonographic and Histological Study
Published 2024-10-01“…Conclusion: Rats given moringa extract had less damage to neuronal architecture in their brains.…”
Get full text
Article -
1267
Z2×Z3 Equivariant Bifurcation in Coupled Two Neural Network Rings
Published 2014-01-01“…We study a Hopfield-type network that consists of a pair of one-way rings each with three neurons and two-way coupling between the rings. The rings have symmetric group Γ=Z3×Z2, which means the global symmetry Z2 and internal symmetry Z3. …”
Get full text
Article -
1268
Conserved multisensory integration of social cues in the thalamus
Published 2025-01-01“…These inputs are mostly processed in the mammalian colliculi and homologous structures in other vertebrates and are subsequently integrated in the posterior thalamus. Increased neuronal activity in this area promotes pro-social behavior across vertebrates. …”
Get full text
Article -
1269
Electroacupuncture combined with trigonelline inhibits pyroptosis in cerebral ischemia-reperfusion by suppressing autophagy via the PI3K/AKT/mTOR signaling pathway
Published 2025-02-01“…Rapa reversed EA in combination with TG-mediated improvement of neuronal damage and suppression of autophagy and pyroptosis in CIRI rats. …”
Get full text
Article -
1270
Effects of Dual Peroxisome Proliferator-Activated Receptors α and γ Activation in Two Rat Models of Neuropathic Pain
Published 2019-01-01“…Cobalt influx assays in cultured dorsal root ganglia (DRG) neurons were used to study the effects of tesaglitazar preincubation on capsaicin-evoked cobalt influx. …”
Get full text
Article -
1271
Antiamnesic and Neurotrophic Effects of Parkia biglobosa (Jacq.) R. Br (Fabaceae) Aqueous Extract on In Vivo and In Vitro Models of Excitotoxicity
Published 2025-01-01“…In the in vitro study, the effect of the extract (5, 10, 19, 40, 77, 153, 306, 615, 1225, and 2450 μg/mL) was assessed on the viability of primary cortical neurons exposed to L-glutamate (0.1 mg/mL). Scopolamine induced memory impairment and increased oxidative stress, neuroinflammation, and neuronal loss. …”
Get full text
Article -
1272
Characterization of Mice Ubiquitously Overexpressing Human 15-Lipoxygenase-1: Effect of Diabetes on Peripheral Neuropathy and Treatment with Menhaden Oil
Published 2021-01-01“…Studies were also performed using dorsal root ganglion neurons isolated from wild-type and transgenic mice. …”
Get full text
Article -
1273
Chronic Rapamycin Prevents Electrophysiological and Morphological Alterations Produced by Conditional Pten Deletion in Mouse Cortex
Published 2025-01-01“…Compared with control mice, CPNs from Pten<sup>-/-</sup> mice demonstrated increased membrane capacitance and time constant in association with increased neuronal somatic size, reduced neuronal firing, and decreased frequency of spontaneous and miniature inhibitory postsynaptic currents, consistent with decreased pre-synaptic GABA release. …”
Get full text
Article -
1274
Artificial Neural Model based on radial basis function networks used for prediction of compressive strength of fiber-reinforced concrete mixes
Published 2019-06-01“…En este documento se presenta la elaboración de un modelo neuronal artificial basado en redes neuronales de funciones de base radial. …”
Get full text
Article -
1275
Allocentric and egocentric spatial representations coexist in rodent medial entorhinal cortex
Published 2025-01-01“…Recently, egocentric spatial representations have also been identified in several brain regions, but evidence for the coexistence of neurons encoding spatial variables in each reference frame within MEC is so far lacking. …”
Get full text
Article -
1276
Unique ultrastructural organization of human rod photoreceptors
Published 2025-01-01“…Abstract Rod and cone photoreceptor cells are specialized neurons responsible for transforming the information reaching the eyes in the form of photons into the language of neuronal activity. …”
Get full text
Article -
1277
Pre-Emptive Treatment of Lidocaine Attenuates Neuropathic Pain and Reduces Pain-Related Biochemical Markers in the Rat Cuneate Nucleus in Median Nerve Chronic Constriction Injury M...
Published 2012-01-01“…Lidocaine pretreatment also reduced the number of injury-induced NPY-like immunoreactive (NPY-LI) fibers and c-Fos-LI neurons within the CN in a dose-dependent manner. …”
Get full text
Article -
1278
Rapid nongenomic estrogen signaling controls alcohol drinking behavior in mice
Published 2024-12-01“…Abstract Ovarian-derived estrogen can signal non-canonically at membrane-associated receptors in the brain to rapidly regulate neuronal function. Early alcohol drinking confers greater risk for alcohol use disorder in women than men, and binge alcohol drinking is correlated with high estrogen levels, but a causal role for estrogen in driving alcohol drinking has not been established. …”
Get full text
Article -
1279
Adenosine deficiency facilitates CA1 synaptic hyperexcitability in the presymptomatic phase of a knockin mouse model of Alzheimer disease
Published 2025-01-01“…Both pharmacologic (adenosine kinase inhibitor) and non-pharmacologic (ketogenic diet) restorations of the adenosine tone successfully normalize hippocampal neuronal activity. Our results demonstrated that neuronal hyperexcitability during the asymptomatic stage of a KI model of Alzheimer disease originated at the synaptic compartment and is associated with adenosine deficient tone. …”
Get full text
Article -
1280
Microglial C/EBPβ-Fcgr1 regulatory axis blocking inhibits microglial pyroptosis and improves neurological recovery
Published 2025-01-01“…In both in-vivo and in-vitro experiments, knocking down Cebpb or Fcgr1, or the pyroptosis inhibitor VX765 inhibited neuronal apoptosis and improved neurological recovery in mice. …”
Get full text
Article