The Many Forms and Functions of Long Term Plasticity at GABAergic Synapses by Arianna Maffei

“…Together with excitatory neurons, inhibitory neurons shape the excitability and dynamic range of neural circuits. …”
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Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder by Itay Tokatly Latzer, Jean-Baptiste Roullet, Wardiya Afshar-Saber, Henry H. C. Lee, Mariarita Bertoldi, Gabrielle E. McGinty, Melissa L. DiBacco, Erland Arning, Melissa Tsuboyama, Alexander Rotenberg, Thomas Opladen, Kathrin Jeltsch, Àngels García-Cazorla, Natalia Juliá-Palacios, K. Michael Gibson, Mustafa Sahin, Phillip L. Pearl

“…While epilepsy and psychiatric behaviors increase in severity with age, communication abilities and motor function tend to improve. iPSCs, which were differentiated into GABAergic neurons, represent the first in vitro neuronal model of SSADHD and express the neuronal marker microtubule-associated protein 2 (MAP2), as well as GABA. …”
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Differences in category information processing between areas TEO and TE of the macaque by Masaumi Shimizu, Shun Katakami, Masato Okada, Yasuko Sugase-Miyamoto, Kazuko Hayashi, Kazuko Hayashi, Keiji Matsuda, Kenichiro Miura, Kenichiro Miura, Mark A. G. Eldridge, Richard C. Saunders, Barry J. Richmond, Narihisa Matsumoto

“…Furthermore, we found that, after cat/dog category training, area TE neuronal populations encode cat and dog category information more strongly than do TEO neurons even in a fixation task (Mann-Whitney U-test, p < 0.05). …”
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Deep-Sea-Derived Isobisvertinol Targets TLR4 to Exhibit Neuroprotective Activity via Anti-Inflammatory and Ferroptosis-Inhibitory Effects by Zi-Han Xu, Ming-Min Xie, Chun-Lan Xie, Xian-Wen Yang, Jun-Song Wang

“…Neuroinflammation and neuronal cell death are leading causes of death in the elderly and underlie various neurodegenerative diseases. …”
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Mitochondrial Dysfunction and α-Synuclein Synaptic Pathology in Parkinson’s Disease: Who’s on First? by Michela Zaltieri, Francesca Longhena, Marina Pizzi, Cristina Missale, PierFranco Spano, Arianna Bellucci

“…Its characteristic neuropathological features encompass the loss of dopaminergic neurons of the nigrostriatal system and the presence of Lewy bodies and Lewy neurites. …”
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Predictive Modeling of Fracture Behavior in Ti6Al4V Alloys Manufactured by SLM Process by Mohsen Sarparast, Majid Shafaie, Mohammad Davoodi, Ahmad Memaran Babakan, Hongyan Zhang

“…Using selected layers and neurons, the system consistently achieved R2-values exceeding 0.99 for both maximum force and fracture displacement. …”
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The Role of Mitochondrial Damage-Associated Molecular Patterns in Chronic Neuroinflammation by Ekta Bajwa, Caitlin B. Pointer, Andis Klegeris

“…Mitochondrial molecules released into the extracellular space following neuronal damage or death may also play a role in these diseases by acting as signaling molecules called damage-associated molecular patterns (DAMPs). …”
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Intestinal microbiome as effective regulator of enteral and central nervous system activity by V. T. Ivashkin, K. V. Ivashkin

“…Objective data indicate the ability of enteric bacteria to regulate electrophysiologic thresholds of enteric neurons and to produce a spectrum of neurotransmitters. …”
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Oxytocin: co-evolution of human and domesticated animals by Yu. E. Herbeck, R. G. Gulevich, D. V. Shepeleva, V. V. Grinevich

“…The neuropeptide oxytocin (OT) and its homologues are produced in specialized neurons located in Vertebrates exclusively in a deep and evolutionarily old part of the forebrain, the hypothalamus. …”
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Revealing excitation-inhibition imbalance in Alzheimer’s disease using multiscale neural model inversion of resting-state functional MRI by Guoshi Li, Li-Ming Hsu, Ye Wu, Andrea C. Bozoki, Yen-Yu Ian Shih, Pew-Thian Yap

“…Recent experimental data have suggested neuronal excitation-inhibition (E-I) imbalance as an essential element of AD pathology, but E-I imbalance has not been systematically mapped out for either local or large-scale neuronal circuits in AD, precluding precise targeting of E-I imbalance in AD treatment. …”
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Huntington’s disease modeling on HEK293 cell line by D. V. Sharipova, T. B. Malankhanova, A. A. Malakhova

“…The mutant HTT protein has an elongated polyglutamine tract and forms aggregates in the nuclei and cytoplasm of the striatal neurons. The pathological processes occurring in the medium spiny neurons of Huntington’s disease patients lead to neurodegeneration and consequently to the death. …”
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Monocarboxylate Transporters: Role and Regulation in Corneal Diabetes by Pawan Shrestha, Amy E. Whelchel, Sarah E. Nicholas, Wentao Liang, Jian-Xing Ma, Dimitrios Karamichos

“…Changes appeared dependent on neuronal density, suggesting that MCTs are very likely critical to the neuronal defects observed in diabetic keratopathy/neuropathy. …”
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A simple and reliable method for claustrum localization across age in mice by Tarek Shaker, Gwyneth J. Dagpa, Vanessa Cattaud, Brian A. Marriott, Mariam Sultan, Mohammed Almokdad, Jesse Jackson

“…Finally, exposure to environmental novelty enhanced the expression of the neuronal activation marker c-Fos in the claustrum region. …”
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Human induced pluripotent stem cell–derived therapies for regeneration after central nervous system injury by Stephen Vidman, Yee Hang Ethan Ma, Nolan Fullenkamp, Giles W. Plant

“…Cells of the neuroectodermal lineage, such as neuronal subpopulations and glia, have been explored with varying degrees of success. …”
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Characteristics of TSPO expression in marmoset EAE by Irene Falk, Dragan Maric, Emily Leibovitch, Pascal Sati, Jennifer Lefeuvre, Nicholas J. Luciano, Joseph Guy, Seung-Kwon Ha, David R. Owen, Franklin Aigbirhio, Paul M. Matthews, Daniel S. Reich, Steven Jacobson

“…Finally, we find expression of TSPO in a subset of neurons, most frequently GLS2 + glutamatergic neurons. …”
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ANN Approach to Predict the Flow Stress of CMn (Nb-Ti-V) Micro Alloyed Steel by Allaoui Abdelhalim, Guedri Abdelmoumene, Darsouni Lamia, Darsouni Abderrazek

“…The optimal LM neural network model with two hidden layer network with ten neurons in the ?rst and ten neurons in the second gives the best predictions is developed. …”
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Single Photon Emission Tomography Imaging in Parkinsonian Disorders: A Review by Paul D. Acton, P. David Mozley

“…Pathological evidence has shown clearly that these disorders are associated with a loss of neurons, particularly in the nigrostriatal dopaminergic pathway. …”
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Potential Neuroprotective Effect of the Endocannabinoid System on Parkinson’s Disease by María Fernanda Urmeneta-Ortíz, Aldo Rafael Tejeda-Martínez, Orfil González-Reynoso, Mario Eduardo Flores-Soto

“…This review provides a comprehensive summary of current clinical and preclinical evidence concerning ECS alterations in PD, along with potential pharmacological targets that may exert the protection of dopaminergic neurons.…”
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Functional Consequences of the Disturbances in the GABA-Mediated Inhibition Induced by Injuriesin the Cerebral Cortex by Barbara Imbrosci, Thomas Mittmann

“…Cortical injuries are often reported to induce a suppression of the intracortical GABAergic inhibition in the surviving, neighbouring neuronal networks. Since GABAergic transmission provides the main source of inhibition in the mammalian brain, this condition may lead to hyperexcitability and epileptiform activity of cortical networks. …”
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From hypoxic pockets to daily routines: linking brain oxygenation and cognitive resilience by Dian Jiao

“…The discovery of hypoxic pockets within the cortical regions has transformed the understanding of cerebral oxygen dynamics, revealing their dual role as both contributors to neuronal adaptation and potential precursors to dysfunction. …”
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