-
1141
Select microbial metabolites in the small intestinal lumen regulates vagal activity via receptor-mediated signaling
Published 2025-02-01“…Serial perfusion of each metabolite class activates both shared and distinct neuronal subsets with varied response kinetics. Metabolite-induced and receptor-dependent increases in vagal activity correspond with the activation of brainstem neurons. …”
Get full text
Article -
1142
Use of Acupuncture in the Rehabilitation Treatment of Patients with Parkinson's Disease
Published 2023-04-01“…The practice of this technique has among its benefits: reducing signs and symptoms, improving motor functions, reducing the need for medication, minimizing medication side effects, slowing the progression of the disease, increasing dopamine levels, decreasing neuronal damage and death, increase cyclophilin levels, increase the number of stem cells and the number of neurons transformed from them, and enhance antioxidant systems. …”
Get full text
Article -
1143
Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View
Published 2012-01-01“…This paper presents its role as a preparation in the development of toxinological studies in the following electrophysiological methods: double-oil-gap technique on isolated giant axon, patch-clamp on DUM (dorsal unpaired median) neurons, microelectrode technique in situ conditions on axon in connective and DUM neurons in ganglion, and single-fiber oil-gap technique on last abdominal ganglion synapse. …”
Get full text
Article -
1144
Substantia nigra alterations in mice modeling Parkinson’s disease
Published 2024-11-01“…However, accumulation of alpha-synuclein and a decrease in the number of dopaminergic neurons in the substantia nigra were found in the B6.Cg-Tg mouse strain. …”
Get full text
Article -
1145
Presynaptic CRF1 Receptors Mediate the Ethanol Enhancement of GABAergic Transmission in the Mouse Central Amygdala
Published 2009-01-01“…The PPF effect of ethanol was abolished in CeA neurons of CRF1 KO mice. The CRF1 antagonist NIH-3 blocked the CRF- and ethanol-induced enhancement of mIPSC frequency in CeA neurons. …”
Get full text
Article -
1146
The edge of chaos is that where consciousness manifests itself through intermittent dynamics
Published 2024-01-01“…The memristive neural model considers two types of neurons, excitatory and inhibitory, and current leakage at body temperature (T = 310 K). …”
Get full text
Article -
1147
Glia and TRPM2 Channels in Plasticity of Central Nervous System and Alzheimer’s Diseases
Published 2016-01-01“…Synaptic plasticity refers to the ability of neurons to strengthen or weaken synaptic efficacy in response to activity and is the basis for learning and memory. …”
Get full text
Article -
1148
Adult Hippocampal Neurogenesis in Alzheimer’s Disease: An Overview of Human and Animal Studies with Implications for Therapeutic Perspectives Aimed at Memory Recovery
Published 2022-01-01“…The mammalian hippocampal dentate gyrus is a niche for adult neurogenesis from neural stem cells. Newborn neurons integrate into existing neuronal networks, where they play a key role in hippocampal functions, including learning and memory. …”
Get full text
Article -
1149
Outcomes of dietary interventions in the prevention and progression of Parkinson's disease: A literature review
Published 2024-12-01“…Factors contributing to this neuronal degeneration include mitochondrial dysfunction, oxidative stress, and neuronal excitotoxicity. …”
Get full text
Article -
1150
From Abnormal Hippocampal Synaptic Plasticity in Down Syndrome Mouse Models to Cognitive Disability in Down Syndrome
Published 2012-01-01“…In this review, we will highlight some of the neurophysiological changes that we believe reduce the ability of trisomic neurons to undergo neuroplasticity-related adaptations. …”
Get full text
Article -
1151
Studying Cortical Plasticity in Ophthalmic and Neurological Disorders: From Stimulus-Driven to Cortical Circuitry Modeling Approaches
Published 2019-01-01“…Unsolved questions in computational visual neuroscience research are whether and how neurons and their connecting cortical networks can adapt when normal vision is compromised by a neurodevelopmental disorder or damage to the visual system. …”
Get full text
Article -
1152
The Extracellular Environment of the CNS: Influence on Plasticity, Sprouting, and Axonal Regeneration after Spinal Cord Injury
Published 2018-01-01“…PNNs associate with the neuronal cell body and proximal dendrites of predominantly parvalbumin-positive interneurons, forming a robust lattice-like structure. …”
Get full text
Article -
1153
HIV-Associated Neurotoxicity: The Interplay of Host and Viral Proteins
Published 2021-01-01“…In-depth research in the pathogenesis of HIV has focused on various mechanisms involved in neuronal dysfunction and associated toxicities ultimately showcasing the involvement of various pathways. …”
Get full text
Article -
1154
Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heterorecept...
Published 2016-01-01“…Anticocaine actions of A2AR agonists can also be produced at A2AR homocomplexes in these antireward neurons, actions in which are independent of D2R signaling. …”
Get full text
Article -
1155
Roles for Prlhr/GPR10 and Npffr2/GPR74 in feeding responses to PrRP
Published 2025-02-01“…Objective: Several groups of neurons in the NTS suppress food intake, including Prlh-expressing neurons (NTSPrlh cells). …”
Get full text
Article -
1156
Imaging the large‐scale and cellular response to focal traumatic brain injury in mouse neocortex
Published 2025-02-01“…Correspondingly, two‐photon calcium imaging in the primary somatosensory cortex (S1) found strong activation of neuropil and neuronal populations during the CCI‐induced travelling wave. …”
Get full text
Article -
1157
The effect of interspike interval statistics on the information gainunder the rate coding hypothesis
Published 2013-08-01“…The question, how much information can be theoreticallygained from variable neuronal firing rate with respect to constantaverage firing rate is investigated.We employ the statistical concept of information based on the Kullback-Leibler divergence,and assume rate-modulated renewal processes as a model of spike trains.We show thatif the firing rate variation is sufficiently small and slow(with respect to the mean interspike interval), the information gaincan be expressed by the Fisher information.Furthermore, under certain assumptions, the smallestpossible information gain is provided by gamma-distributed interspikeintervals.The methodology is illustrated and discussed on severaldifferent statistical models of neuronal activity.…”
Get full text
Article -
1158
Rifaximin Improves Visceral Hyperalgesia via TRPV1 by Modulating Intestinal Flora in the Water Avoidance Stressed Rat
Published 2020-01-01“…The changes of TRPV1 in peripheral and central neurons of rats were detected by immunofluorescence, western blot method, and RT-PCR. …”
Get full text
Article -
1159
Acupuncture for Parkinson’s Disease: Efficacy Evaluation and Mechanisms in the Dopaminergic Neural Circuit
Published 2021-01-01“…Parkinson’s disease (PD) is a chronic and progressive neurodegenerative disease caused by degeneration of dopaminergic neurons in the substantia nigra. Existing pharmaceutical treatments offer alleviation of symptoms but cannot delay disease progression and are often associated with significant side effects. …”
Get full text
Article -
1160
Single- versus Multiobjective Optimization for Evolution of Neural Controllers in Ms. Pac-Man
Published 2013-01-01“…Three different architectures of PAESNet were investigated, namely, PAESNet with fixed number of hidden neurons (PAESNet_F), PAESNet with varied number of hidden neurons (PAESNet_V), and the PAESNet with multiobjective techniques (PAESNet_M). …”
Get full text
Article