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2181
Salivary Acetylcholinesterase Activity Is Increased in Parkinson’s Disease: A Potential Marker of Parasympathetic Dysfunction
Published 2015-01-01“…Future studies are needed to elucidate whether this parameter reflects the extent of neuronal damage and parasympathetic denervation in the salivary glands of PD patients.…”
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2182
Expanded taxonomies of human memory
Published 2025-01-01“…All of the above take place in the human brain, driven by neurons and the processes of long-term potentiation and depression. …”
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2183
PD_EBM: An Integrated Boosting Approach Based on Selective Features for Unveiling Parkinson's Disease Diagnosis With Global and Local Explanations
Published 2025-01-01“…The increasing prevalence of PD and its significant impact on the motor neurons of the brain impose a substantial burden on the healthcare system. …”
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2184
Operant Discriminative Learning and Evidence of Subtelencephalic Plastic Changes After Long-Term Detelencephalation in Pigeons
Published 2003-01-01“…Morphometric analysis revealed a decreased number of neurons and increased vascularity, associated with increases in the perimeter (p<0.001) in the nucleus rotundus. …”
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2185
The Effect of Different Doses of Botulinum Toxin on Masseter Muscle in Patients with Bruxism.
Published 2022-02-01“…It acts by inhibiting the release of acetylcholine from cholinergic neurons. Botulinum toxin has been used for management of bruxism, which is a parafunctional disorder and characterized by clenching or grinding of the teeth or both. …”
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2186
MAP4 kinase-regulated reduced CLSTN1 expression in medulloblastoma is associated with increased invasiveness
Published 2025-01-01“…Calsynthenin 1 (CLSTN1) is a neuronal protein involved in cell-cell interaction, vesicle trafficking, and synaptic signaling. …”
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2187
Optimal sigmoid function models for analysis of transspinal evoked potential recruitment curves recorded from different muscles.
Published 2025-01-01“…Recruitment input-output curves of transspinal evoked potentials that represent the net output of spinal neuronal networks during which cortical, spinal and peripheral inputs are integrated as well as motor evoked potentials and H-reflexes are used extensively in research as neurophysiological biomarkers to establish physiological or pathological motor behavior and post-treatment recovery. …”
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2188
Narcolepsy treatment: from exorcism and bloodletting to modern therapy with histamine receptor inverse agonists
Published 2020-09-01“…It was not until the late 20th century, when narcolepsy was perceived as a central hypersomnia due to partial or complete loss of hypocretin-secreting neurons in the hypothalamus, that effective symptomatic treatment emerged. …”
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2189
Differential Proteomic Analysis Predicts Appropriate Applications for the Secretome of Adipose-Derived Mesenchymal Stem/Stromal Cells and Dermal Fibroblasts
Published 2018-01-01“…This approach led to the recognition of distinct functions related to the conditioned medium of ASCs and DFs, with the former being involved in the regulation of neuronal death and apoptosis and the latter in bone metabolism and ossification. …”
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2190
Developing a brain inspired multilobar neural networks architecture for rapidly and accurately estimating concrete compressive strength
Published 2025-01-01“…The MLANN framework employs various architectures of hidden layers, referred to as “lobes,” each with a unique arrangement of neurons to optimize data processing, reduce training noise, and expedite training time. …”
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2191
Recent advances in genetics of aggressive behavior
Published 2018-09-01“…In addition, there is evidence that the hypothalamic-pituitary system genes (OXT, OXTR, AVPR1A, AVPR1B), the sex hormone receptors genes (ER1, AR), neurotrophin (BDNF) and neuronal apoptosis genes (CASP3, BAX) may also be involved in development of aggressive behavior. …”
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2192
Extramacrochaetae regulates Notch signaling in the Drosophila eye through non-apoptotic caspase activity
Published 2024-11-01“…These effects included acceleration of the morphogenetic furrow, failure of R7 photoreceptor cell specification, and delayed differentiation of non-neuronal cone cells. Within emc mutant clones, Notch signaling was elevated in the morphogenetic furrow, increasing morphogenetic furrow speed. …”
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2193
p38 MAPK Endogenous Inhibition Improves Neurological Deficits in Global Cerebral Ischemia/Reperfusion Mice
Published 2022-01-01“…The cerebral infarction area and volume were assessed and analyzed by 2,3,5-triphenyltetrazolium chloride (TTC) staining. p38 MAPK and caspase-3 were detected by western blotting. Neuronal apoptosis was measured using TUNEL staining. …”
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2194
Pharmacodynamics of TRPV1 Agonists in a Bioassay Using Human PC-3 Cells
Published 2014-01-01“…TRPV1 is a multimodal channel mainly expressed in sensory neurons. We aimed to explore the pharmacodynamics of the TRPV1 agonists, capsaicin, natural capsaicinoids, and piperine in an in vitro bioassay using human PC-3 cells and to examine desensitization and the effect of the specific antagonist SB366791. …”
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2195
Exploring novel and potent glycogen synthase kinase-3β inhibitors through systematic drug designing approach
Published 2025-02-01“…Abstract Significant implications of glycogen synthase kinase-3β (GSK-3β) have been reported in various neuronal disorders and malignant cancers. GSK-3β modulates diverse protein targets through phosphorylation, and its aberrant activity leads to neurological complications as well as tumour onset. …”
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2196
Role of PPARs in Progression of Anxiety: Literature Analysis and Signaling Pathways Reconstruction
Published 2020-01-01“…Among three PPAR isoforms, PPARG demonstrates the highest expression in CNS, where it can be found in neurons, astrocytes, and glial cells. Herein, the highest PPARG expression occurs in amygdala. …”
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2197
A peripheral subepithelial network for chemotactile processing in the predatory sea slug Pleurobranchaea californica.
Published 2024-01-01“…Sensory nerve spikes and cilia cluster spikes were not identifiable as generated by the same neurons. Ciliary clusters likely drive the sensory nerve spikes via SeN, mediating appetitive and stimulus place codes to CNS. …”
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2198
RESULTS OF EXPERIMENTAL INFECTION OF TURKEYS WITH A/DUCK/ALTAI/469/14 H5N1 STRAIN OF AVIAN INFLUENZA VIRUS
Published 2018-10-01“…Immunohistochemical analysis showed the greatest distribution of the influenza virus antigen in the cerebral endothelium, cerebellar Purkinje neurons, acinar cells of the pancreas and in myocardiocytes of the heart. …”
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2199
Chromatin remodeling in oligodendrogenesis
Published 2021-09-01“…As they go through the stages of specification and differentiation – from multipotent neuronal cells in the ventricular zone of the neural tube to mature myelinating oligodendrocytes as well as during migration along blood vessels to their destination – cells undergo dramatic changes in the pattern of gene expression. …”
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2200
Shenfu Injection Protects Brain Injury in Rats with Cardiac Arrest through Nogo/NgR Pathway
Published 2022-01-01“…The ultrastructure of neuronal cells in Shenfu group had relatively complete cell membranes and more vesicles than those in the model group. …”
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