Inhibition of S100A8/A9 ameliorates neuroinflammation by blocking NET formation following traumatic brain injury by Guihong Shi, Yiyao Cao, Jianye Xu, Bo Chen, Xu Zhang, Yanlin Zhu, Liang Liu, Xilei Liu, Luyuan Zhang, Yuan Zhou, Shenghui Li, Guili Yang, Xiao Liu, Fanglian Chen, Xin Chen, Jianning Zhang, Shu Zhang

“…S100A8/A9-enriched neutrophils were present in the injured brain tissue of TBI patients, and elevated plasma levels of S100A8/A9 were correlated with poorer neurological function. Furthermore, using a TBI mouse model, we demonstrated that treatment with the selective S100A8/A9 inhibitor Paquinimod significantly mitigated neuroinflammation and neuronal death, thereby improving the prognosis of TBI mice. …”
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Adverse events in the nervous system associated with blinatumomab: a real-world study by Wen Gao, Jingwei Yu, Yifei Sun, Zheng Song, Xia Liu, Xue Han, Lanfan Li, Lihua Qiu, Shiyong Zhou, Zhengzi Qian, Xianhuo Wang, Huilai Zhang

“…The median time to onset (TTO) for neurological events was 3 days (range, 1 ~ 21). The highest fatality rate for neurological events was observed for increased intracranial pressure disorders, which also had the highest co-occurrence rate with cytokine release syndrome (CRS). …”
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Minimally invasive exoscope-assisted coccygectomy: A novel approach for chronic refractory coccydynia by Barnabas Obeng-Gyasi, Danielle Wilmes, Matthew P. Blackwell, Jae H. Kwon, Gordon Mao

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Health care utilization patterns of patients enrolled in an interdisciplinary program for back pain by Sara Davin, Psy.D., MPH, Brittany Lapin, PhD., MPH, Belinda Udeh, PhD, Sarah Rispinto, PhD, Nicolas R. Thompson, MS, Ryan Honomichl, PhD, Andre Machado, MD, Irene L. Katzan, MD

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Resolution of tremor associated with brainstem arachnoid cyst following surgical intervention: A case report by Andrey Rostislavovich Sitnikov, Rezida Maratovna Galimova, Dmitriy Konstantinovich Krekotin

“…Introduction: Intracranial arachnoid cysts located in the brainstem are extremely rare. Neurological symptoms usually depend on the location of the cyst and present with varying degrees of motor deficit and cranial nerve palsy. …”
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Chiari malformation with concurrent papilledema: a patient-level meta-analysis of case reports and case series by Alejandro Pando, Daniel J. Valdivia, Daniel A. Brenner, Mohammed Ali Alvi, Hai Sun, James K. Liu, Ira Goldstein

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Methylprednisolone substituted lipid nanoparticles deliver C3 transferase mRNA for combined treatment of spinal cord injury by Haoru Dong, Zongxing He, Shiyi Cai, Haiqiang Ma, Lili Su, Jianfeng Li, Huiying Yang, Rong Xie

“…Abstract Spinal cord injury (SCI), characterized by the disruption of neural pathways and an increase in inflammatory cell infiltration, leads to profound and lasting neurological deficits, with a high risk of resulting in permanent disability. …”
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The crucial role of 5hmC in neuroprotection and repair after cerebrovascular injury by Yanina Tsenkina

“… Cerebrovascular injuries, such as stroke and other vascular insults to the brain, present significant challenges to neurological function and recovery. Within the complex realm of epigenetic modifications, hydroxymethylation emerges as a crucial factor in orchestrating mechanisms for neuroprotection and repair following such injuries. …”
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The Correlation of Hemostatic Parameters with the Development of Early Sepsis-Associated Encephalopathy. A Retrospective Observational Study by Scarlatescu Florin, Scarlatescu Ecaterina, Tomescu Dana Rodica, Bartos Daniela

“…Sepsis-associated encephalopathy (SAE) is one of the most common complications seen both in early and late stages of sepsis, with a wide spectrum of clinical manifestations ranging from mild neurological dysfunction to delirium and coma. The pathophysiology of SAE is still not completely understood, and the diagnosis can be challenging especially in early stages of sepsis and in patients with subtle symptoms.…”
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Systemic Lupus Erythematosus with Concurrent Thrombotic Thrombocytopenic Purpura: A Case Report of Diagnostic Challenges and Management Approaches by Sonu Rahul Tej Gaddam, Manideep Katta, Sumana Simarla, Pruthvi Raj Kukunoor, Manichandana Katta

“…This condition can manifest as a pentad of symptoms that includes fever, thrombocytopenia, Microangiopathic Haemolytic Anemia (MAHA), renal disease and neurological disease. Authors hereby, detail the case of a 29-year-old female with a rare combination of TTP and Systemic Lupus Erythematosus (SLE), which presents challenges in diagnosis, clinical progression and therapeutic response. …”
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From non-human to human primates: a translational approach to enhancing resection, safety, and indications in glioma surgery while preserving sensorimotor abilities by Matteo Gambaretti, Matteo Gambaretti, Luca Viganò, Luca Viganò, Matteo Gallo, Giovanni Pratelli, Tommaso Sciortino, Lorenzo Gay, Marco Conti Nibali, Alberto Luigi Gallotti, Alberto Luigi Gallotti, Leonardo Tariciotti, Luca Mattioli, Lorenzo Bello, Lorenzo Bello, Gabriella Cerri, Gabriella Cerri, Marco Rossi, Marco Rossi, Marco Rossi

“…The main goal, and, at the same time, the main challenge, of oncological neurological surgery is to avoid permanent neurological deficit while reaching maximal resection, particularly when the tumor infiltrates the neural network subserving motor functions. …”
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Multi-dimensional outcomes following extracorporeal cardiopulmonary resuscitation by Tharusan Thevathasan, Vanessa Wahl, Joshua Boettel, Megan Kenny, Julia Paul, Sophie Selzer, Abdulla Al Harbi, Eva-Maria Dorsch, Heinrich Audebert, Matthias Rose, Christoph Paul Klapproth, Sonia Lech, Katharina Schmitt, Steffen Desch, Ulf Landmesser, Ralf Westenfeld, Fabian Voss, Carsten Skurk

“…Background: Recent trials suggested that extracorporeal cardio-pulmonary resuscitation (ECPR) with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) or “ECMELLA” (VA-ECMO plus Impella®) may improve short-term survival and neurological outcomes in selected patients with refractory cardiac arrest. …”
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Late Onset Hepatic Encephalopathy after Living Donor Liver Transplant: Successful Reversal by Plug Embolization of Shunt—A Report of Two Cases by Shahnawaz Bashir, Dibyalochan Praharaj, Adnan Khan, Subhash Gupta, Pragati Gakher

“…Plug-assisted embolization of PS shunt led to significant improvement in their clinical and neurological symptoms, highlighting the importance of monitoring for PS shunts in long-term LT follow-up.…”
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Identification of Neurons Containing Calcium-Permeable AMPA and Kainate Receptors Using Ca2+ Imaging by Sergei Gaidin, Artem Kosenkov, Valery Zinchenko, Bakytzhan Kairat, Arailim Malibayeva, Sultan Tuleukhanov

“…Calcium-permeable AMPA receptors (CP-AMPARs) and kainate receptors (CP-KARs) play crucial roles in synaptic plasticity and are implicated in various neurological processes. Current methods for identifying neurons expressing these receptors, such as electrophysiological recordings and immunostaining, have limitations in throughput or inability to distinguish functional receptors. …”
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Preterm nutrition and brain development by Chiara Nava, Gianluca Lista, Enrica Lupo

“…Further studies are needed to better understand the mechanisms of action of different nutrients on brain development in the preterm infant and thus the effects on long-term neurological outcomes.…”
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Single-staged Surgical Correction of Kyphotic Deformity due to Dorsal Spinal Tuberculosis in Pediatric Patients: Outcome Analysis by Mageswaran Shanmugavelu, Makesh Ram Sriraghavan, Prabhu Aloy, Poornima Kumararaja, Sai Vinay Bharadwaj Namala

“…It can result in the collapse of the affected vertebrae, leading to deformities such as kyphosis and sagittal imbalance; the deformity and progression can be worse in the pediatric age-group due to their growth spurt. Neurological complications can occur when the tubercular infection affects the spinal cord or the nerve roots. …”
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Renal function and clinical outcomes in survivors of out-of-hospital cardiac arrest by Hao-Wei Lee, Ming-Jen Kuo, Pai-Feng Hsu, I-Hsin Lee, Chih-Yu Yang, Teh-Fu Hsu, Chorng-Kuang How, Yenn-Jiang Lin, Chin-Chou Huang

“…Clinical outcomes included neurological outcomes and all-cause mortality. Result: A total of 258 patients were enrolled, including 35 patients with underlying end-stage renal disease (ESRD). …”
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Characteristics, clinical manifestations and management of leprosy in KwaZulu-Natal, South Africa: A 20-year retrospective study by J S Sons, Z N Mkhize, N C Dlova, C Aldous, P R Bhat, A V Chateau

“…Debilitating neurological complications were found in one-fifth of patients. …”
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The protective role of GLP-1 in neuro-ophthalmology by Sohum Sheth, Aashay Patel, Marco Foreman, Mohammed Mumtaz, Akshay Reddy, Ramy Sharaf, Siddharth Sheth, Brandon Lucke-Wold

“…Therefore, this article aims to review the literature on the neurologic and neuro-ophthalmic role of glucagon-like peptide 1 (GLP-1). …”
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Mercury and its Associated Impacts on Environment and Human Health: A Review by Alex, Saturday

“…Mercury has profound neurological, endocrine, reproductive, and fetotoxicity effects. …”
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