Feedback of aggregate patient-reported outcomes (PROs) data to clinicians and hospital end users: findings from an Australian codesign workshop process by Monique F Kilkenny, Dominique A Cadilhac, Shaun L Hancock, Violet Marion, Paulette Kelly, Sibilah Breen, Benjamin Clissold, Lauren Sanders, Olivia Francis Ryan, Penina Gunzburg, Shae Cooke, Lauren Guy

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Clinical Significance of Negative Costimulatory Molecule PD-1/PD-L1 on Peripheral Blood Regulatory T Cell Levels among Patients with Pulmonary Tuberculosis by Chenchen Yang, Fanchao Dai, Rexiti Pulati, Yan Jiao, Qian Xu

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Cellular and immune landscape of chronic liver diseases: insights from immunophenotyping by Shaghayegh Soleimani, Shaghayegh Soleimani, Ozgur Albayrak, Kayra Somay, Hong Yang, Buket Yigit, Burge Ulukan, Dila Atak, Murat Akyildiz, Metehan Gursoy, Elif Demirtas, Adil Mardinoglu, Adil Mardinoglu, Atay Vural, Atay Vural, Murat Dayangac, Mujdat Zeybel

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A comparative analysis in monitoring 24-hour urinary copper in wilson disease: sampling on or off treatment? by Isabelle Mohr, Patrick Lamade, Christophe Weber, Viola Leidner, Sebastian Köhrer, Alexander Olkus, Matthias Lang, Andrea Langel, Patrischia Dankert, Melanie Greibich, Silke Wolf, Holger Zimmer, Patrick Michl, Aurélia Poujois, Karl Heinz Weiss, Uta Merle

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Ac2-26 Alleviates Brain Injury after Cardiac Arrest and Cardiopulmonary Resuscitation in Rats via the eNOS Pathway by Jing Gong, Qi-Hang Tai, Guang-Xiao Xu, Xue-Ting Wang, Jing-Li Zhu, Xiao-Qing Zhao, Hai-Bin Sun, Dan Zhu, Wei Gao

“…Rats received Ac2-26, Ac2-26+L-NIO, or saline after CPR. Neurologic function was assessed at baseline, 24, and 72 hours after CPR. …”
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Association between the hemoglobin A1c/High-density lipoprotein cholesterol ratio and stroke incidence: a prospective nationwide cohort study in China by Chaojuan Huang, Hongtao You, Yuyang Zhang, Ligang Fan, Xingliang Feng, Naiyuan Shao

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The Prevalence of Depression Among Parkinson’s Disease Patients in Saudi Arabia: A Cross-Sectional Study by Al-Qahtani Z, Alqahtani ASM, Alzuhairi AMS, Qarah M, Alqarni AA, Alqahtani AOM, AlShehri FAA, Alqathanin MAA, Alshahrani OMO, Alqahtani MAF, Mahmood SE

“…Zainah Al-Qahtani,1 Abdulrahman Saad M Alqahtani,2 Abdulmohsin Mohammed S Alzuhairi,3 Mohammed Qarah,4 Albara A Alqarni,3 Abdulaziz Othman M Alqahtani,5 Fahad Abdullah A AlShehri,3 Muath Abdullah A Alqathanin,6 Omair Mohammed O Alshahrani,3 Mohammed Ali F Alqahtani,5 Syed Esam Mahmood7 1Neurology Section, Internal Medicine Department, College of Medicine, King Khalid University, Abha, 61421, Saudi Arabia; 2Aseer Cluster Health, Abha, Saudi Arabia; 3King Khalid University, Abha, Saudi Arabia; 4Public Health Department, Saudi Board of Preventive Medicine, Madinah, Saudi Arabia; 5College of Medicine King Khalid University, Abha, Saudi Arabia; 6Internal Medicine Department, Saudi Board of Internal Medicine, Abha, Saudi Arabia; 7Department of Family and Community Medicine, College of Medicine, King Khalid University, Abha, 61421, Saudi ArabiaCorrespondence: Syed Esam Mahmood, Department of Family and Community Medicine, College of Medicine, King Khalid University, Abha, 62529, Saudi Arabia, Email smahmood@kku.edu.saBackground and Aim: Depression is thought to affect up to half of Parkinson’s patients at some point during their illness, while anxiety is reported by about 40% of PD patients. …”
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SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease by Mridula Bhalla, Jinhyeong Joo, Daeun Kim, Jeong Im Shin, Yongmin Mason Park, Yeon Ha Ju, Uiyeol Park, Seonguk Yoo, Seung Jae Hyeon, Hyunbeom Lee, Junghee Lee, Hoon Ryu, C. Justin Lee

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Distinct Circle of Willis anatomical configurations in healthy preterm born adults: a 3D time-of-flight magnetic resonance angiography study by Julien Greggio, Christina Malamateniou, Kelly Pegoretti Baruteau, Constantino Carlos Reyes-Aldasoro, Odaro J. Huckstep, Jane M. Francis, Wilby Williamson, Paul Leeson, Adam J. Lewandowski, Winok Lapidaire

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Clinicopathological and predictive value of MAIT cells in non-small cell lung cancer for immunotherapy by Dongyan Shi, Lin Lin, Yun Chen, Jian Liu, Lin Shi, Jinying Lu, Da Zhong, Meijuan Song, Wenhua You, Wen-Hui Li

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Transition from pediatric to adult health services: A survey of challenges, needs, and preferences of youths and parents by Eric Racine, François Ouimet, Rocio Gissel Gutierrez Rojas, Marie-José Clermont, Anne Fournier

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Cardiovascular disease attenuates the protective effect of folate on global cognitive function in an elderly population: a cross-sectional study by Jianqiang Zhang, Di Yue, Huifeng Zhang

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Examining the Use of Machine Learning Algorithms to Enhance the Pediatric Triaging Approach by Aljubran HJ, Aljubran MJ, AlAwami AM, Aljubran MJ, Alkhalifah MA, Alkhalifah MM, Alkhalifah AS, Alabdullah TS

“…Hussain J Aljubran,1 Maitham J Aljubran,2 Ahmed M AlAwami,1 Mohammad J Aljubran,3 Mohammed A Alkhalifah,4 Moayd M Alkhalifah,5 Ahmed S Alkhalifah,6 Tawfik S Alabdullah7 1College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 2Pediatric Department, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia; 3Department of Energy Science & Engineering, Stanford University, Stanford, CA, USA; 4Emergency Medicine Department, Johns Hopkins Aramco Healthcare, Al-Hasa, Saudi Arabia; 5Neurology Unit, Neurosciences Institute, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia; 6Pediatric Department, Qatif Central Hospital, Al Qatif, Saudi Arabia; 7Pediatric Emergency Medicine, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi ArabiaCorrespondence: Hussain J Aljubran, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, 34212, Saudi Arabia, Tel +966540800696, Email hussainjawad1420@gmail.com Maitham J Aljubran, Pediatric Department, King Faisal Specialist Hospital & Research Centre, Riyadh, 12212, Saudi Arabia, Tel +966544177737, Email mjmj77550@gmail.comPurpose: Triage systems play a vital role in effectively prioritizing patients according to the seriousness of their condition. …”
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PLL-g-HPA Hydrogel Loaded Human Umbilical Cord Mesenchymal Stem Cells Promote Burn Wound Healing in Rat Model by Regulating Inflammation Response by Tian L, Wang Z, Lei T, Feng L, Li Y, Wang K, Zhang Y, Zhang C, Liu J, Xing H, Ren W

“…Linqiang Tian,1,2 Zhaodong Wang,1,2 Tingting Lei,1,3 Lili Feng,1 Yanyan Li,1 Kunxi Wang,1 Yue Zhang,1 Chengshu Zhang,4 Jie Liu,1 Hongxia Xing,3 Wenjing Ren5 1Henan Key Medical Laboratory of Traumatics and Orthopaedics’ Research, The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, People’s Republic of China; 2Department of Orthopedics Surgery, The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, People’s Republic of China; 3Department of Neurology, The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, People’s Republic of China; 4Department of Burn and Plastic Surgery, General Hospital of PINGMEI SHENMA Group, Pingdingshan, People’s Republic of China; 5Clinical Medical Center of Tissue Engineering and Regeneration, Xinxiang Medical University, Xinxiang, People’s Republic of ChinaCorrespondence: Hongxia Xing; Wenjing Ren, Email xhxwh02@163.com; xxmu_rwj@163.comPurpose: Treatment of severe burn wound injury remains a significant clinical challenge as serious infections/complex repair process and irregulating inflammation response. …”
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Evaluation of three-dose fosfomycin tromethamine in the treatment of patients with urinary tract infections: an uncontrolled, open-label, multicentre study by Shan Chen, Yong Yang, Bo Yang, Ming Chen, Kai Zhang, Yi Wang, Lu-Dong Qiao, Bo Zheng, Hong-Feng Guo, Yuan-Jie Niu, Ben-Kang Shi, Wei-Min Yang, Xiao-Kun Zhao, Xiao-Feng Gao

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Risk of Symptomatic Intracranial Hemorrhage After Mechanical Thrombectomy in Randomized Clinical Trials: A Systematic Review and Meta-Analysis by Abdullah Reda, Alireza Hasanzadeh, Sherief Ghozy, Hossein Sanjari Moghaddam, Tanin Adl Parvar, Mohsen Motevaselian, Ramanathan Kadirvel, David F. Kallmes, Alejandro Rabinstein

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Effect of Esketamine on Cognitive Recovery After Propofol Sedation for Outpatient Colonoscopy: A Randomized Clinical Trial by Liu D, Gao X, Zhuo Y, Cheng W, Yang Y, Wu X, Yang H, Yao Y

“…Deshan Liu,1,* Xiuchai Gao,2,* Yifen Zhuo,3,* Wanjie Cheng,4 Ying Yang,4 Xiaoyan Wu,4 Huobao Yang,5 Yusheng Yao4,5 1Department of Neurology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, Fujian, People’s Republic of China; 2Department of Anesthesiology, Fujian Xiapu County Hospital, Xiapu, Fujian, People’s Republic of China; 3Department of Anesthesiology, Xiamen Haicang Hospital, Xiamen, Fujian, People’s Republic of China; 4Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, Fujian, People’s Republic of China; 5Fujian Provincial Key Laboratory of Critical Care Medicine, Fuzhou, Fujian, People’s Republic of China*These authors contributed equally to this workCorrespondence: Huobao Yang; Yusheng Yao, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, 134 Dongjie Street, Fuzhou, Fujian, 350001, People’s Republic of China, Email paulyang003@fjmu.edu.cn; fjslyys@126.comPurpose: While esketamine shows promise as an adjunct in procedural sedation, its impact on postoperative cognitive recovery remains incompletely characterized. …”
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MT2A promotes angiogenesis in chronically ischemic brains through a copper–mitochondria regulatory mechanism by Ni Mo, Chuyang Tai, Yang Yang, Cong Ling, Baoyu Zhang, Lei Wei, Cian Yao, Hui Wang, Chuan Chen

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Noninvasive oxygenation and ventilation strategies for viral acute respiratory failure: a comprehensive systematic review and meta-analysis by Fredy Leonardo Carreño-Hernández, Sergio Prieto, Daniela Abondando, Jairo Alejandro Gaitán, Yenny Rocío Cárdenas -Bolívar, Adriana Beltrán, Jorge Iván Alvarado-Sánchez, Joseph L. Nates

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Enhanced therapeutic effects of hypoxia-preconditioned mesenchymal stromal cell-derived extracellular vesicles in renal ischemic injury by Fei Yuan, Jie Liu, Liang Zhong, Pengtao Liu, Ting Li, Kexin Yang, Wei Gao, Guangyuan Zhang, Jie Sun, Xiangyu Zou

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