Surveillance of tick-borne encephalitis virus foci in Slovakia: A seroprevalence study in ruminants combined with virus detection in ticks by Martina Ličková, Bronislava Víchová, Markéta Derdáková, Monika Sláviková, Sabína Fumačová Havlíková, Dana Zubriková, Diana Selyemová, Michal Chvostáč, Lucia Blaňarová, Viktória Čabanová, Veronika Vaňová, Lucia Šulejová, Jana Kerlik, Tomáš Szemes, Katarína Šoltys, Boris Klempa

“…The tick-borne encephalitis virus (TBEV) is an important human pathogen that causes tick-borne encephalitis, a potentially fatal neurological disease. Human infections occur through tick bites or after the consumption of raw milk products from infected animals, causing alimentary outbreaks representing a significant public health problem in Slovakia. …”
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Inducing aggresome and stable tau aggregation in Neuro2a cells with an optogenetic tool by Shigeo Sakuragi, Tomoya Uchida, Naoki Kato, Boxiao Zhao, Toshiki Takahashi, Akito Hattori, Yoshihiro Sakata, Yoshiyuki Soeda, Akihiko Takashima, Hideaki Yoshimura, Gen Matsumoto, Hiroko Bannai

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Efficacy and Safety of Pramipexole Sustained Release versus Immediate Release Formulation for Nocturnal Symptoms in Chinese Patients with Advanced Parkinson’s Disease: A Pilot Stud... by Haiyan Zhou, Shuhua Li, Hongmei Yu, Shenggang Sun, Xinhua Wan, Xiaodong Zhu, Chun-Feng Liu, Ling Chen, Wei Xiang, Yaqing Sun, Haibo Chen, Shengdi Chen

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Integrating bulk and single-cell RNA sequencing data: unveiling RNA methylation and autophagy-related signatures in chronic obstructive pulmonary disease patients by Shi-Xia Liao, Lan-Ying Zhang, Ling-Mei Shi, Huai-Yu Hu, Yan-Hui Gu, Ting-Hua Wang, Yao Ouyang, Peng-Peng Sun

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Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein by Marie-Lynn Cuypers, Tom Jaspers, Jarne Clerckx, Simon Leekens, Christopher Cawthorne, Guy Bormans, Frederik Cleeren, Nick Geukens, Bart De Strooper, Maarten Dewilde

“…Abstract Background Therapeutic antibodies for the treatment of neurological disease show great potential, but their applications are rather limited due to limited brain exposure. …”
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Advances in physiological and clinical relevance of hiPSC-derived brain models for precision medicine pipelines by Negin Imani Farahani, Negin Imani Farahani, Negin Imani Farahani, Lisa Lin, Lisa Lin, Lisa Lin, Shama Nazir, Shama Nazir, Shama Nazir, Alireza Naderi, Alireza Naderi, Alireza Naderi, Leanne Rokos, Leanne Rokos, Leanne Rokos, Anthony Randal McIntosh, Anthony Randal McIntosh, Lisa M. Julian, Lisa M. Julian, Lisa M. Julian, Lisa M. Julian

“…Continued advances in tissue engineering combined with innovations in genomics, high-throughput screening and imaging strengthen the physiological relevance of hiPSC models and thus their ability to uncover disease mechanisms, therapeutic vulnerabilities, and tissue and fluid-based biomarkers that will have real impact on neurological disease treatment. True physiological understanding, however, necessitates integration of hiPSC-neural models with patient biophysical data, including quantitative neuroimaging representations. …”
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Evaluating plasma biomarkers NfL, GFAP, GDF15, and FGF21 as indicators of disease severity in Charcot–Marie Tooth patients by Dace Pretkalnina, Dace Pretkalnina, Dace Pretkalnina, Elizabete Kenina, Elizabete Kenina, Linda Gailite, Dmitrijs Rots, Dmitrijs Rots, Kaj Blennow, Kaj Blennow, Henrik Zetterberg, Henrik Zetterberg, Henrik Zetterberg, Henrik Zetterberg, Henrik Zetterberg, Henrik Zetterberg, Viktorija Kenina, Viktorija Kenina, Viktorija Kenina

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Dual antiplatelet therapy with ticagrelor vs clopidogrel in patients with TIA or minor stroke with or without symptomatic carotid artery stenosis: a post hoc analysis of the CHANCE... by Yongjun Wang, Yilong Wang, Xingquan Zhao, Jing Jing, Hao Li, Xia Meng, Anxin Wang, Yong Jiang, Jinxi Lin, Qin Xu, Xuewei Xie, Pan Chen

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Peripheral proteinopathy in neurodegenerative diseases by Bin Xu, Xia Lei, Ying Yang, Jiayi Yu, Jun Chen, Zhi Xu, Keqiang Ye, Jing Zhang

“…Abstract Proteinopathies in neurology typically refer to pathological changes in proteins associated with neurological diseases, such as the aggregation of amyloid β and Tau in Alzheimer’s disease, α-synuclein in Parkinson’s disease and multiple system atrophy, and TAR DNA-binding protein 43 in amyotrophic lateral sclerosis and frontotemporal dementia. …”
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Ruptured Suprasellar Dermoid Cyst presenting with Chemical Meningitis and Blindness by Lakshya Varshney, Laxminarayan Tripathy, Harsh Jain, Sunandan Basu, Mohammad Sarwar

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Electroacupuncture for Decorticate Rigidity of the Upper Limbs in a Patient with Anoxic Brain Damage by WooSang Jung, SeungWon Kwon, SeongUk Park, SangKwan Moon, JungMi Park, ChangNam Ko, KiHo Cho

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Apelin/APJ system: a novel promising target for anti-oxidative stress in stroke by Weilin Xu, Weilin Xu, Jun Yan, Zachary D. Travis, Cameron Lenahan, Liansheng Gao, Liansheng Gao, Haijian Wu, Haijian Wu, Jingwei Zheng, Jingwei Zheng, Jianmin Zhang, Jianmin Zhang, Anwen Shao, Anwen Shao, Jun Yu, Jun Yu

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Key considerations in setting up a therapeutic plasma exchange service for neurology patients  by Nicole Japzon, Aneliya Takova, Viva Levee, Ruth Han, Jenny McDonald, Benjamin Sacks, Sinead Rosser, Katharine Hunt, Laura Zambreanu, Michael Lunn, Jennifer Spillane

“…Therapeutic plasma exchange (TPE) is effective in the treatment of both neurological and non-neurological diseases. It is highly efficacious when used appropriately but has significant associated risks. …”
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Thrombolysis, time-to-treatment and in-hospital outcomes among young adults with ischaemic stroke in China: findings from a nationwide registry study in China by Yong-Jun Wang, Xin Yang, Qi Zhou, Hao Li, Xia Meng, Yong Jiang, Li-Ping Liu, Yi-long Wang, Hong-Qiu Gu, Zi-Xiao Li, Xing-Quan Zhao, Chun-Juan Wang, Chelsea Liu, Hai-yan Wang, Ying-Yu Jiang

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Sensorineural Hearing Loss and Celiac Disease: A Coincidental Finding by Umberto Volta, Gian Gaetano Ferri, Roberto De Giorgio, Angela Fabbri, Claudia Parisi, Laura Sciajno, Alessandra Castellari, Erica Fiorini, Maria Piscaglia, Giovanni Barbara, Alessandro Granito, Antonio Pirodda

“…BACKGROUND: Celiac disease (CD) can be associated with a variety of extraintestinal manifestations, including neurological diseases. A new neurological correlation has been found between CD and sensorineural hearing loss (SNHL).…”
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Evaluation of Brain SPECT with 99mTc-TRODAT-1 in the Differential Diagnosis of Parkinsonism by Giorgio Fabiani, Carlos Henrique Ferreira Camargo, Raul Martins Filho, Gabriel Sampaio Froehner, Hélio Afonso Ghizoni Teive

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Subtle changes in Purkinje cell firing in Purkinje cell-specific Dyt1 ΔGAG knock-in mice by Hong Xing, Pallavi Girdhar, Yuning Liu, Fumiaki Yokoi, David E. Vaillancourt, Yuqing Li

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Small ubiquitin-like modifiers inhibitors lower blood pressure via ERK5/KLF2-dependent upregulation of the eNOS/NO pathway by Tang Nannan, Li Jiatong, Wang Zhuo, Zuo Jinlu, Zhang Zifeng, Huang Di, Han Yannan, Chen Yuqing, Sun Yilin, Li Xiang, Mu Ruxue, Ma Qingxue, Zhang Jie, Wu Jiaying, Wang He, Zhao Hongxia, Dong Xingli, Wang Zhiguo, Liu Yu, Zhao Dan, Yang Baofeng

“…Small ubiquitin-like modifiers (SUMO)ylation is a dynamic and reversible post-translational modification playing pivotal roles in the regulation of cancer, diabetes, heart failure, and neurological diseases. However, whether SUMO inhibitors also have anti-hypertension effect remains yet to be explored.…”
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Characterization of Human-Induced Neural Stem Cells and Derivatives following Transplantation into the Central Nervous System of a Nonhuman Primate and Rats by Mengjia Li, Zhengbo Wang, Tianqi Zheng, Tianzhuang Huang, Baoguo Liu, Deqiang Han, Sumei Liu, Bochao Liu, Mo Li, Wei Si, Y. Alex Zhang, Yuyu Niu, Zhiguo Chen

“…The results suggest that iNSCs and derivatives have a potential to be used for the treatment of neurological diseases.…”
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Intracalvariosseous injection: an approach for central nervous system drug delivery through skull bone marrow with a preclinical research in strokeResearch in context by Wenqian Liu, Mo Yang, Nanxing Wang, Xiangrong Liu, Chaoyu Wang, Kaibin Shi, Fu-Dong Shi, Yuesong Pan, Mingjun Zhang, Zhiwei Sun, Yongjun Wang, Yilong Wang

“…Summary: Background: Central nervous system (CNS) accessibility constitutes a major hurdle for drug development to treat neurological diseases. Existing drug delivery methods rely on breaking the blood-brain barrier (BBB) for drugs to penetrate the CNS. …”
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