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Mitigating bias in AI mortality predictions for minority populations: a transfer learning approach
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E3 ubiquitin ligase SYVN1 as a promising therapeutic target for diverse human diseases
Published 2025-02-01“…Consequently, SYVN1 plays a crucial role in both normal human physiology and the pathogenesis of various diseases, such as oncogenesis, cardiovascular disorders, immune regulation, skeletal anomalies, and neurological diseases. This review synthesizes recent findings regarding the physiological and pathophysiological roles of SYVN1, offering new insights into potential strategies for the prevention and treatment of human diseases, as well as suggesting avenues for future drug development. …”
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Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation
Published 2013-01-01“…During pregnancy, the previous responses promoted by viral infections and other proinflammatory conditions are common and might predispose the offspring to develop psychiatric disorders and neurological diseases. Such disorders could eventually be potentiated by stress and might be part of the etiopathogenesis of CNS dysfunctions including autism spectrum disorders and schizophrenia.…”
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Cerebral Responses to Acupuncture at GV24 and Bilateral GB13 in Rat Models of Alzheimer’s Disease
Published 2018-01-01“…Acupuncture has been widely used in China to treat neurological diseases including Alzheimer’s disease (AD). …”
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Modified ‘Xingnao Kaiqiao’ acupuncture technique shortens the recovery time of comatose patients
Published 2025-12-01“…Background This study was conducted to analyse the therapeutic effect of the modified ‘Xingnao Kaiqiao’ acupuncture technique in the recovery of comatose patients, as well as the clinical factors that may influence recovery from coma.Methods Diagnostic and therapeutic data from 166 patients in a coma due to neurological diseases were retrospectively collected. Eighty-seven comatose patients received conventional treatment, and 79 patients received conventional treatment + the modified ‘Xingnao Kaiqiao’ acupuncture technique. …”
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Therapeutic Use of Botulinum Toxin in Neurorehabilitation
Published 2012-01-01“…The use of BTX for the rehabilitation of children with obstetrical brachial plexus palsy and in treating sialorrhea which can complicate the course of some severe neurological diseases such as amyotrophic lateral sclerosis and Parkinson's disease is also addressed. …”
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Evaluating the Cause of Death in Obese Individuals: A Ten-Year Medical Autopsy Study
Published 2015-01-01“…Obese individuals were statistically more likely to die from pulmonary embolism and liver disease and less likely to die from neurologic diseases and nonischemic heart disease. Conclusion. …”
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Human platelet lysate: a potential therapeutic for intracerebral hemorrhage
Published 2025-01-01“…Human platelet lysates (HPL) are abundant in bioactive factors, and numerous studies have demonstrated their beneficial effects on neurological diseases, including their anti-neuroinflammatory ability, anti-oxidant effects, maintenance of blood–brain barrier integrity, and promotion of neurogenesis. …”
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Neurotropic Tick-Borne Flavivirus in Alpine Chamois (<i>Rupicapra rupicapra rupicapra</i>), Austria, 2017, Italy, 2023
Published 2025-01-01“…The European subtype of tick-borne encephalitis virus (TBEV-Eur; species <i>Orthoflavivirus encephalitidis</i>, family <i>Flaviviridae</i>) was the only tick-borne flavivirus present in central Europe known to cause neurologic disease in humans and several animal species. …”
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Exploring the microbiota-gut-brain axis: impact on brain structure and function
Published 2025-02-01“…By gaining a deeper understanding of the MGBA, it may be possible to facilitate research into microbial-based pharmacological interventions and therapeutic strategies for neurological diseases.…”
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Crosstalk between the Ketogenic Diet and Epilepsy: From the Perspective of Gut Microbiota
Published 2019-01-01“…In particular, the significant involvement of the autoimmune processes in the development of epilepsy, one of the most serious and widespread neurological diseases, has led to a suggested link with the gut microbiome. …”
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Positron Emission Tomography—Computer Tomography Scan Used as a Monitoring Tool Following Cellular Therapy in Cerebral Palsy and Mental Retardation—A Case Report
Published 2013-01-01“…Cerebral palsy (CP) is one of the non-progressive neurological diseases caused by damage to the brain tissue at birth, which leads to physical, cognitive and perceptive symptoms. …”
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Fluorescent Particles Based on Aggregation-Induced Emission for Optical Diagnostics of the Central Nervous System
Published 2025-01-01“…This review focuses on the application of AIEgens in CNS imaging, exploring their roles in the diagnosis of various neurological diseases. We will discuss the evolution and conclude with an outlook on the future challenges and opportunities for AIEgens in clinical diagnostics and therapeutics of CNS disorders.…”
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Common lipidomic signatures across distinct acute brain injuries in patient outcome prediction
Published 2025-01-01“…Lipidomic alterations have been associated with various neurological diseases. Examining temporal changes in serum lipidomic profiles, irrespective of injury type, reveals promising prognostic indicators. …”
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Elevated Osteopontin Levels in Mild Cognitive Impairment and Alzheimer’s Disease
Published 2013-01-01“…Cerebrospinal fluid (CSF) and plasma samples were obtained from 35 AD patients, 31 MCI patients, and 20 other noninflammatory neurologic diseases (OND). Concentrations of OPN in the CSF and plasma were determined by enzyme-linked immunosorbent assay. …”
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Expansion of Natural Killer Cells in Peripheral Blood in a Japanese Elderly with Human T-Cell Lymphotropic Virus Type 1-Related Skin Lesions
Published 2014-01-01“…Natural killer (NK) cells were proposed to play an important role in the pathogenesis of human T-cell lymphotropic virus type 1- (HTLV-1-) associated neurologic disease. Our patient was a 77-year-old Japanese man, who had been treated for infective dermatitis associated with HTLV-1 for nearly 10 years. …”
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deutetrabenazine for the treatment of chorea associated with Huntington’s disease
Published 2022-06-01“…Chorea is a movement disorder present in multiple neurologic diseases that causes involuntary and irregular muscle movements theorized to be stemming from high dopamine levels. …”
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