Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus by Natalia Avaliani, Ulrich Pfisterer, Andreas Heuer, Malin Parmar, Merab Kokaia, My Andersson

“…Direct conversion of human somatic cells to induced neurons (iNs), using lineage-specific transcription factors has opened new opportunities for cell therapy in a number of neurological diseases, including epilepsy. In most severe cases of epilepsy, seizures often originate in the hippocampus, where populations of inhibitory interneurons degenerate. …”
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Phospholipase D, a Novel Therapeutic Target Contributes to the Pathogenesis of Neurodegenerative and Neuroimmune Diseases by Weiwei Zhang, Feiqi Zhu, Jie Zhu, Kangding Liu

“…In this review, family members, characterizations, structure, functions and related signaling pathways, and therapeutic values of PLD was summarized, then five representative diseases including Alzheimer disease (AD), Parkinson’s disease (PD), etc. were selected as examples to tell the involvement of PLD in these neurological diseases. Notably, recent advances in the development of tools for studying PLD therapy envisaged novel therapeutic interventions. …”
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Neurophobia: causes and methods to reduce it by Š. Jukna, Rūta Mameniškienė

“…Understanding the causes of neurophobia and promoting neurophilia would not only increase the willingness of medical students to choose the profession of neurologist, but also improve the care and treatment of patients with neurological diseases. …”
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Nonlocal Intracranial Cavity Extraction by José V. Manjón, Simon F. Eskildsen, Pierrick Coupé, José E. Romero, D. Louis Collins, Montserrat Robles

“…Automatic and accurate methods to estimate normalized regional brain volumes from MRI data are valuable tools which may help to obtain an objective diagnosis and followup of many neurological diseases. To estimate such regional brain volumes, the intracranial cavity volume (ICV) is often used for normalization. …”
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Ethical Implications in the Use of Embryonic and Adult Neural Stem Cells by Rodrigo Ramos-Zúñiga, Oscar González-Pérez, Ana Macías-Ornelas, Vivian Capilla-González, Alfredo Quiñones-Hinojosa

“…A whole range of treatment possibilities originates from this knowledge that potentially can be used for different neurological diseases in humans. Although this is an encouraging scenario, it implies that the human brain is the object of such study, as well as its potential manipulation and transplantation. …”
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PLGA scaffold combined with MSCs transplantation improved neural function and brain tissue structure in rats with traumatic brain injury by Na Xu, Zihuan Sun, Weikang Guan, Yiming Liu, Yun Gao, Chaoxian Yang

“…Mesenchymal stem cells (MSCs) have been used to treat various neurological diseases, but they face challenges when filling large tissue defects. …”
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Melatonin and Ischemic Stroke: Mechanistic Roles and Action by Syed Suhail Andrabi, Suhel Parvez, Heena Tabassum

“…Melatonin has been implicated in various neurological diseases because of its antioxidative, antiapoptotic, and anti-inflammatory properties. …”
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Promising Neuroprotective Effects of Dracocephalum Species: Mechanistic Perspectives by Marjan Talebi, Alireza Ghassempour, Afsoon Feizi, Seyed Abdulmajid Ayatollahi, Mehrdad Faizi

“… Neurological diseases have important effects on morbidity and mortality rates. …”
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Nucleolar PARP-1 Expression Is Decreased in Alzheimer’s Disease: Consequences for Epigenetic Regulation of rDNA and Cognition by Jianying Zeng, Jenny Libien, Fatima Shaik, Jason Wolk, A. Iván Hernández

“…Thus, we hypothesize that PARP-1 may be altered in postmortem hippocampus of individuals with AD compared to age-matched controls without neurologic disease. We found a reduced level of PARP-1 nucleolar immunohistochemical staining in hippocampal pyramidal cells in AD. …”
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Cyclic Peptides as Protein Kinase Modulators and Their Involvement in the Treatment of Diverse Human Diseases by Lorena Martínez-Alcantar, Laura Hernández-Padilla, Alma Laura Díaz-Pérez, Lizbeth Guadalupe Villalón-Magallán, Mayra Xóchitl Durán-Maldonado, César Díaz-Pérez, Marlene E. Campos-Morales, Citlali Figueroa-Guzmán, Jesús Campos-García

“…Nevertheless, modifications in the expression due to mutations or their dysregulation can lead to diseases, including autoimmune disorders, cardiovascular problems, diabetes, neurological diseases, and cancers. Cyclic ultra-short peptides are amazing structures with unique properties. …”
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Transthyretin-Related Familial Amyloidosis Polyneuropathy with Spinal Cord Damage: A Case Report by Liu H, Huang C, Du Y, Liu J, Ren X, Wang H, Ye J, Zhou H, Duan Z

“…Hailin Liu,1,* Chao Huang,1,* Yanjiao Du,1 Jiacheng Liu,1,2 Xiangyang Ren,1 Huilin Wang,1 Jingna Ye,1 Haitao Zhou,1 Zhihui Duan1 1Department of Neurology, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang Cerebrovascular Disease (Stroke) Clinical Medical Research Center, Regional Medical Center for Neurological Diseases of Henan Province, Luoyang, People’s Republic of China; 2Xinxiang Medical College, Xinxiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhihui Duan, Department of Neurology, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang Cerebrovascular Disease (Stroke) Clinical Medical Research Center, Regional Medical Center for Neurological Diseases of Henan Province, Xigong District, Luoyang, Henan, 471000, People’s Republic of China, Tel/Fax +0086-0379-63892044, Email 54487843@qq.comIntroduction: Transthyretin protein-related familial amyloidosis polyneuropathy (TTR-FAP) is an autosomal dominant genetic disease caused by mutations in the TTR gene. …”
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Corrigendum: Research progress of breast cancer surgery during 2010–2024: a bibliometric analysis by Jiawei Kang, Nan Jiang, Munire Shataer, Tayier Tuersong

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Suppression of epileptic seizures by transcranial activation of K+-selective channelrhodopsin by Xiaodong Duan, Chong Zhang, Yujie Wu, Jun Ju, Zhe Xu, Xuanyi Li, Yao Liu, Schugofa Ohdah, Oana M. Constantin, Yifan Pan, Zhonghua Lu, Cheng Wang, Xiaojing Chen, Christine E. Gee, Georg Nagel, Sheng-Tao Hou, Shiqiang Gao, Kun Song

“…Abstract Optogenetics is a valuable tool for studying the mechanisms of neurological diseases and is now being developed for therapeutic applications. …”
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The emerging role of 12/15-lipoxygenase in ischemic stroke by Xuening Wang, Qiuji Shao, Yuan Gao

“…Furthermore, we list currently available inhibitors of 12/15-LOX and the preclinical or clinical applications, offering novel insights for the early diagnosis, prognosis evaluation, and targeted therapy in neurological diseases.…”
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Hybrid Carcinoma of the Larynx: A Case Report (Adenoid Cystic and Adenocarcinoma) and Review of the Literature by Ilias Karasmanis, John K. Goudakos, Iosif Vital, Thomas Zarampoukas, Victor Vital, Konstantinos Markou

“…During the evaluation of the neurologic disease, a subglottic mass of the larynx was revealed accidentally in the imaging examination. …”
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A Study on the Inflammatory Response of the Brain in Neurosyphilis by Qiyu Zhang, Jie Ma, Jia Zhou, Hanlin Zhang, Mansheng Li, Huizi Gong, Yujie Wang, Heyi Zheng, Jun Li, Ling Leng

“…Abstract Neurosyphilis (NS) is a clinical condition caused by infection of the central nervous system (CNS) by Treponema pallidum (Tp) that can lead to asymptomatic meningitis and more serious neurological diseases, such as dementia and blindness. However, current studies on the pathogenesis of NS are limited. …”
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Alkaloid-rich fraction from Luffa cylindrica Linn fruit enhances memory and mitigates oxidative stress in hippocampus of ozone-exposed sprague Dawley rat via LCMS and network pharm... by Ankul Singh S, Chitra Vellapandian

“…It provides a holistic understanding of the medicinal properties of ARF, encouraging further exploration for potential therapeutic interventions in neurological diseases.…”
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Recent advances in bio-integrated electrochemical sensors for neuroengineering by Shulin Chen, Tzu-Li Liu, Yizhen Jia, Jinghua Li

“…Detecting and diagnosing neurological diseases in modern healthcare presents substantial challenges that directly impact patient outcomes. …”
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Structural insights into human topoisomerase 3β DNA and RNA catalysis and nucleic acid gate dynamics by Xi Yang, Xuemin Chen, Wei Yang, Yves Pommier

“…Defects in TOP3B lead to severe neurological diseases. We present a series of cryo-EM structures of human TOP3B with its cofactor TDRD3 during cleavage and rejoining of DNA or RNA, thus elucidating the roles of divalent metal ions and key enzyme residues in each step of the catalytic cycle. …”
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MicroRNA Profiling: From Dark Matter to White Matter, or Identifying New Players in Neurobiology by Anna M. Krichevsky

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