Chlorpromazine and Promethazine (C+P) Reduce Brain Injury after Ischemic Stroke through the PKC-δ/NOX/MnSOD Pathway by Sichao Guo, Fengwu Li, Melissa Wills, James Yip, Alexandra Wehbe, Changya Peng, Xiaokun Geng, Yuchuan Ding

“…Cerebral ischemia-reperfusion (I/R) incites neurologic damage through a myriad of complex pathophysiological mechanisms, most notably, inflammation and oxidative stress. …”
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Risk Factors for Prolonged Length of Stay of Older Patients in an Academic Emergency Department: A Retrospective Cohort Study by Özcan Sir, Gijs Hesselink, Mara Van Den Bogaert, Reinier P. Akkermans, Yvonne Schoon

“…Risk factors for prolonged LOS of older patients at the ED were follows: higher number (more than one) of consultations (OR [odds ratio] 2.4, CI [confidence interval] 2.0-2.91), or diagnostic interventions (OR 1.5, CI 1.4-1.7); presenting complaints of a neurological (OR 2.2, CI 1.0-4.5) or internal medicine focus (OR 2.6, CI 1.4-4.6); patients with an altered consciousness (OR 3.3, CI 1.6-6.6); treatment by physicians of the departments of surgery (OR 3.4, CI 2.2-5.2), internal medicine (OR 2.6, CI 1.9-3.7), or pulmonology (OR 2.2, CI 1.4-3.6); and urgency category of ≥ U1. …”
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Association of hypertension and plant-based dietary patterns on cognitive impairment: a nationwide cohort study in China by Fang Liang, Jialin Fu, Gabrielle Turner-McGrievy, Yechuang Wang, Kai Ding, Jing Zeng, Justin B Moore, Rui Li

“…Adherence to healthful PBD pattern could be used to prevent or mitigate adverse neurological effects in the hypertensive population.…”
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Impact of gender on the prognosis of carotid body tumor after surgical resection by Huanrui Hu, Yuwei Xiang, Bin Huang, Ding Yuan, Yi Yang, Jichun Zhao

“…Although tumor size and Shamblin classification had positive relationships with neurological complications and intraoperative blood loss, they did not affect the overall survival rate of patients, which was only influenced by remote metastasis (P = .007) and local recurrence (P = .008). …”
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From pain to meningitis: bacteria hijack nociceptors to promote meningitis by Huazhen Liu, Xingxing Kong, Yuqin Zeng, Jinyun Chen, Zhanpeng Chen, Lanlan Liu, Quan Ma, Xuhui Liu, Xuhui Liu, Shuihua Lu

“…This condition carries a high risk of mortality and severe neurological sequelae, such as cognitive impairment and epilepsy. …”
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Genetic and molecular mechanisms of hydrocephalus by Xuehai Deng, Xuehai Deng, Yiqian Chen, Yiqian Chen, Qiyue Duan, Qiyue Duan, Jianlin Ding, Jianlin Ding, Zhong Wang, Zhong Wang, Junchi Wang, Xinlong Chen, Liangxue Zhou, Long Zhao

“…Hydrocephalus is a neurological condition caused by aberrant circulation and/or obstructed cerebrospinal fluid (CSF) flow after cerebral ventricle abnormal dilatation. …”
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Characterization of Stroke Patients in an Intensive Care Unit by Marianela Planes Fajardo, Georgia Díaz-Perera Fernández, Maylín Isabel Alonso Martínez, Aurora Calzada Fajardo

“…Stroke is the main neurological cause of death and the third most common cause of death in the world. …”
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An Atypical Presentation of Childhood Paraganglioma with Seizures: A Case Report and Review of the Literature by Elizabeth Eberechi Oyenusi, Uzoamaka Felicia Nwigbo, Oluwadamilola Moromoke Oladipo, Blessing Ebele Kene-Udemezue, Kasarachi Pauline Akowundu, Khadijah Omobusola Oleolo-Ayodeji, Oluwaseun Adunni Afoke, Funmilayo Oluwatoyin Babatunde, Felix Makinde Alakaloko, Gabriel Kolawole Asiyanbi, Ezekiel Olayiwola Ogunleye, Abiola Olufunmilayo Oduwole, Foluso Ebun Afolabi Lesi

“…Cardiovascular manifestations predominate but neurological symptoms like seizures can occur requiring a high index of suspicion for prompt diagnosis and treatment. …”
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Rare Manifestation of a c.290 C>T, p.Gly97Glu VCP Mutation by Nivedita U. Jerath, Cameron D. Crockett, Steven A. Moore, Michael E. Shy, Conrad C. Weihl, Tsui-Fen Chou, Tiffany Grider, Michael A. Gonzalez, Stephan Zuchner, Andrea Swenson

“…Our patient reflects the clinical heterogeneity of VCP mutations, as his neurological localization is a spectrum between a lower motor neuron disorder and a hereditary axonal peripheral neuropathy such as CMT2. …”
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Case report of neurobrucellosis: a rare complication and neuroimaging findings of a common disease by Yu Zhang, Yu Zhang, Xiao-Yi Zou, Xiao-Yi Zou, Ling Liu

“…Background and objectiveNeurobrucellosis is a rare neurological disorder characterized by diverse clinical manifestations. …”
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Comorbidity in in patients with relapsing-remitting multiple sclerosis by O.V. Somilo, S.O. Makarov, O.I. Kalbus

“…All patients were assessed using the Multiple Sclerosis Neurological Disability Severity Scale (EDSS). Study participants were divided into two groups – Group 1 and Group 2 – based on EDSS scores. …”
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The role of isoniazid dosage and NAT2 gene polymorphism in the treatment of tuberculous meningitis by Yi Jian, Yuhang Bao, Fashuang Yang, Mei Zhu

“…Univariate analysis showed significant differences between groups in baseline focal neurological impairment and disability or mortality by the 3rd and 12th months. …”
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The role of olfactory transport in the penetration of manganese oxide nanoparticles from blood into the brain by A. V. Romashchenko, M. B. Sharapova, К. N. Morozova, E. V. Kiseleva, K. E. Kuper, D. V. Petrovskii

“…The accumulation of NPs in CNS can provoke many neurological diseases; therefore, the understanding of its mechanisms is of both academic and practical interest. …”
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Exosomes of Antler Mesenchymal Stem Cells Improve Postoperative Cognitive Dysfunction in Cardiopulmonary Bypass Rats through Inhibiting the TLR2/TLR4 Signaling Pathway by Chun Yang, Shengnan Sun, Qi Zhang, Jia Guo, Tengfei Wu, Ying Liu, Min Yang, Yan Zhang, Yinghua Peng

“…AMSC-derived exosomes reduced neurological damage and brain damage and prevent apoptosis in CPB rats. …”
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The functional instrumental test of flexion-extension motion in the radiocarpal joint: reference parameters by Dmitry V. Skvortsov, Danila A. Lobunko, Galina Е. Ivanova

“…The research sample was a group of 15 healthy volunteers (5 males and 10 females aged from 23 to 33 years), not having any joint diseases or neurological disorders. The research was carried out within a period of one year (2022–2023). …”
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Dystonia caused by ANO3 variants is due to attenuated Ca2+ influx by ORAI1 by Jiraporn Ousingsawat, Khaoula Talbi, Hilario Gómez-Martín, Anne Koy, Alberto Fernández-Jaén, Hasan Tekgül, Esra Serdaroğlu, Juan Darío Ortigoza-Escobar, Rainer Schreiber, Karl Kunzelmann

“…Abstract Background Dystonia is a common neurological hyperkinetic movement disorder that can be caused by mutations in anoctamin 3 (ANO3, TMEM16C), a phospholipid scramblase and ion channel. …”
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The potential of stem cell therapy in Multiple Sclerosis treatment: a review by Sorina Amarculesei, Ava O'Meara Cushen, Cathy Brougham

“…There are currently 371 clinical trials involving mesenchymal stem cells and 462 clinical trials involving adipose derived stem cells, with research focused on skeletal applications, wound healing, and to a lesser degree, haematological and neurological disorders. Although adipose derived stem cells could represent a valuable treatment option for many diseases, several drawbacks to their advancement remain, such as their pro-tumorigenic properties, possible negative alteration of the immune system, and the difficulty in assessing their migration patterns once administered in vivo. …”
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Does Clostridium Perfringens Epsilon Toxin Mimic an Auto-Antigen Involved in Multiple Sclerosis? by Marie-Lise Gougeon, Valérie Seffer, Cezarela Hoxha, Elisabeth Maillart, Michel R. Popoff

“…Multiple sclerosis (MS) is a chronic immune-mediated neurological disorder, characterized by progressive demyelination and neuronal cell loss in the central nervous system. …”
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Diagnostic Validation for Participants in the Washington State Parkinson Disease Registry by Hojoong M. Kim, James B. Leverenz, Daniel J. Burdick, Sindhu Srivatsal, Jennifer Pate, Shu-Ching Hu, Steven P. Millard, Marie Y. Davis, Ali Samii, Cyrus P. Zabetian

“…Those who responded were invited to undergo an interview and neurological examination performed by a PD specialist. …”
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Preclinical use of a clinically-relevant scAAV9/SUMF1 vector for the treatment of multiple sulfatase deficiency by Maximiliano Presa, Rachel M. Bailey, Somdatta Ray, Lauren Bailey, Saurabh Tata, Tara Murphy, Pierre-Alexandre Piec, Harold Combs, Steven J. Gray, Cathleen Lutz

“…Abstract Background Multiple Sulfatase Deficiency (MSD) is a rare inherited lysosomal storage disorder characterized by loss of function mutations in the SUMF1 gene that manifests as a severe pediatric neurological disease. There are no available targeted therapies for MSD. …”
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