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3281
The Hidden Economic Consequences of Migraine to the UK Government: Burden-of-Disease Analysis Using a Fiscal Framework
Published 2023-10-01“…**Background:** Migraine is a highly prevalent and incapacitating neurological disorder associated with the highest global disability burden in people aged 15 to 49 years. …”
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3282
Chronic prostatitis/chronic pelvic pain syndrome induces metabolomic changes in expressed prostatic secretions and plasma
Published 2025-01-01“…Overall, metabolomic alterations in the EPS and plasma of patients were primarily associated with oxidative damage, energy metabolism abnormalities, neurological impairment, and immune dysregulation. These alterations may be associated with chronic pain, voiding symptoms, reduced fertility, and depression in CP/CPPS. …”
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3283
Initial Treatment of Meningocele and Myelomeningocele Lesion in Children
Published 2025-01-01“…The disease significantly impacts survival and neurological outcomes in children. The purpose of this study is to investigate the effect of in-time assessment and surgical intervention on functional outcomes in children with MMC. …”
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3284
A ketogenic diet regulates microglial activation to treat drug addiction
Published 2025-01-01“…In recent years, a ketogenic diet (KD) was shown to have therapeutic benefits as a dietary therapy for a variety of neurological disorders. With respect to drug addiction, studies have shown that a KD can alleviate glucose metabolism disorders caused by alcohol use disorders by increasing ketone metabolism, thereby reducing withdrawal symptoms. …”
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3285
Mental Health in Children with Cerebral Palsy: Does Screening Capture the Complexity?
Published 2013-01-01“…Children with cerebral palsy (CP), one of the most common childhood neurological disorders, often have associated medical and psychological symptoms. …”
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3286
Assessment of Stroke Case-fatality, Disability, Perceived Needs and Barriers for Care among First-ever Stroke Patients Attending a Tertiary Care Neuro-specialty Center in India: A...
Published 2025-01-01“…Stroke survivors require care and support, particularly during the crucial 3 months post-stroke when 95% of functional neurological recovery occurs. To estimate case-fatality and extent of disability, assess perceived needs, barriers, and unmet needs for care, and ascertain pathways to care post-discharge (at 3 months) among first-ever stroke patients attending a tertiary care neuro-specialty center in India. …”
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3287
Outcome of spine surgery in the context of spinal metastatic disease: The National Surgical Quality Improvement Program
Published 2024-12-01“…In addition, 28.6% of patients experienced a prolonged hospital stay, with significant predictors including chemotherapy, surgical urgency, dependent status, preoperative hematocrit, neurological deficits, preoperative albumin levels, and surgical complexity. …”
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3288
NURSING CARE OF CONTINUOUS URINARY INCONTINENCE IN THE ELDERLY POST-ISCHEMIC STROKE A CASE REPORT
Published 2022-05-01“…Introduction : Continuous urinary incontinence is the continued and uncontrolled passing of urine without distension and a feeling of fullness in the bladder due to neurological dysfunction. This condition is often found in the elderly post-ischemic stroke. …”
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3289
A macro-transection model of brain trauma for neuromaterial testing with functional electrophysiological readouts
Published 2025-12-01“…Functional recovery in penetrating neurological injury is hampered by a lack of clinical regenerative therapies. …”
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3290
Fat droplets in the cerebrospinal fluid (CSF) spaces of the brain
Published 2024-11-01“…Pneumocephalus is the presence of air in the epidural, subdural, or subarachnoid space and can cause confusion, nausea, seizures and focal neurological symptoms. A careful analysis of the neuroimaging findings in the CT with or without MRI is important in making a correct diagnosis of a ruptured dermoid cyst versus pneumocephalus.…”
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3291
The efficacy of an allosteric modulator of the alpha 7 nicotinic acetylcholine receptor in a murine model of stroke
Published 2025-02-01“…Using a murine transient middle cerebral artery occlusion (tMCAO) model, we sought to evaluate the neurotherapeutic efficacy of a positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor (α7-nAChR), PNU-120596 (PNU), specifically examining whether PNU would modulate stroke-induced neurological dysfunction and neuropathology, with modulation of neuroinflammation as a possible mechanism.MethodsYoung male C57BL/6J mice received a subcutaneous injection of 20mg/kg of vehicle (DMSO) or PNU-120596 immediately after reperfusion, and infarct area and Bederson score were analyzed 24 hours post-stroke. …”
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3292
Targeting Oxidative Stress Injury after Ischemic Stroke in Conscious Rats: Limited Benefits with Apocynin Highlight the Need to Incorporate Long Term Recovery
Published 2013-01-01“…Apocynin treatment (50 mg/kg i.p.) commencing 1 hour prior to stroke and 24 and 48 hours after stroke significantly reduced infarct volume in the cortex by ~ 60%, but had no effect on striatal damage or neurological deficits. In situ detection of reactive oxygen species (ROS) using dihydroethidium fluorescence revealed that increased ROS detected in OX-42 positive cells following ischemia was reduced in apocynin-treated rats by ~ 51%, but surprisingly increased in surrounding NeuN positive cells of the same rats by ~ 27%, in comparison to the contralateral hemisphere. …”
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3293
Are Onconeural Antibodies a Clinical Phenomenology in Paraneoplastic Limbic Encephalitis?
Published 2013-01-01“…Paraneoplastic neurological syndromes (PNSs) occur in patients with cancer and can cause clinical symptoms and signs of dysfunction of the nervous system that are not due to a local effect of the tumor or its metastases. …”
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3294
Clinical Practice Guidelines of Traditional Chinese Medicine Rehabilitation for Incomplete Paraplegia
Published 2021-10-01“…Rehabilitation assessment includes: spinal cord injury neurological function assessment, muscle tone assessment, muscle strength assessment, psychological function assessment, activities of daily living and ability assessment and so on. …”
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3295
Role of Microbes and Nanomaterials in the Removal of Pesticides from Wastewater
Published 2022-01-01“…Long-term exposure to pesticides can cause neurological disorders, reproductive complications, cancer, immunological, and pulmonary diseases. …”
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3296
CHILDREN ON ANTI EPILEPTIC DRUGS HAVE LOW SERUM CALCIUM AND RAISED ALKALINE PHOSPHATASE LEVELS
Published 2023-04-01“… Objective: Epilepsy is a common neurological disorder in children requiring long-term therapy using anti-epileptic drugs (AEDs). …”
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3297
Endovascular intervention in patients with blunt traumatic thoracic aortic injury: Early results
Published 2024-03-01“…Patients who were under 22 and over 70 years of age, those who underwent emergency TEVAR, died in a hospital emergency, and had penetrating aortic injury, head traumas with neurological symptoms and requiring intervention, aortic pathology other than Type B aortic dissection, or aortic rupture were excluded from the study. …”
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3298
Nonpharmacological Modulation of Chronic Inflammation in Parkinson’s Disease: Role of Diet Interventions
Published 2019-01-01“…Recent evidence suggests that neuroinflammation in PD might originate in the intestine and the bidirectional communication between the central and enteric nervous system, the so-called “gut-brain axis,” has received growing attention due to its contribution to the pathogenesis of neurological disorders. Diet targets mediators of inflammation with various mechanisms and combined with dopaminergic treatment can exert various beneficial effects in PD. …”
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3299
Intrinsic Gene Expression Correlates of the Biophysically Modeled Diffusion Magnetic Resonance Imaging Signal
Published 2025-03-01“…Magnetic resonance imaging (MRI) is a powerful tool to identify the structural and functional correlates of neurological illness but provides limited insight into molecular neurobiology. …”
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3300
Developmental inequity and the impact of pesticide exposure on gut and brain health in developing nations – a Brazilian perspective
Published 2025-02-01“…The gastrointestinal tract, home to a complex microbiome, plays an essential role in immune regulation and neurological functions. Pesticide exposure, which may begin prenatally through maternal pathways and continue postnatally, has the potential to disrupt this microbiome and affect critical neurodevelopmental processes, likely altering lifelong health outcomes. …”
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