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141
Transformers for Neuroimage Segmentation: Scoping Review
Published 2025-01-01“… BackgroundNeuroimaging segmentation is increasingly important for diagnosing and planning treatments for neurological diseases. Manual segmentation is time-consuming, apart from being prone to human error and variability. …”
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142
Functional Role of Milk Fat Globule-Epidermal Growth Factor VIII in Macrophage-Mediated Inflammatory Responses and Inflammatory/Autoimmune Diseases
Published 2016-01-01“…Chronic inflammation is considered to be one of the major causes of serious diseases, including a number of autoimmune/inflammatory diseases, cancers, cardiovascular diseases, and neurological diseases. Milk fat globule-epidermal growth factor 8 (MFG-E8) is a secreted protein found in vertebrates and was initially discovered as a critical component of the milk fat globule. …”
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143
Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity
Published 2019-01-01“…Because GDNF has been effective in animal models of Parkinson’s disease, stroke, epilepsy, and Huntington’s disease, among other debilitating neurodegenerative diseases, encapsulated cell-based delivery of GDNF might represent one innovative means of slowing the neural degeneration seen in a myriad of currently untreatable neurological diseases.…”
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144
Targeting Histone Deacetylases: A Novel Approach in Parkinson’s Disease
Published 2015-01-01“…Indeed, it is becoming increasingly evident that chromatin acetylation status can be impaired during the neurological disease conditions. The acetylation and deacetylation of histone proteins are carried out by opposing actions of histone acetyltransferases (HATs) and histone deacetylases (HDACs), respectively. …”
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145
Exploring environmental factors contributing to Parkinson’s disease in AfrAbian populations
Published 2024-12-01“…Climate change, driven mainly by global warming, is linked to detrimental health impacts, including an increased frequency and intensity of heat waves. Neurological diseases, including neurodegenerative syndromes like Alzheimer’s disease, Parkinson’s disease, and motor neuron illnesses, have been increasingly seen and recorded in the scientific literature. …”
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146
Trained Innate Immunity by Repeated Low-Dose Lipopolysaccharide Injections Displays Long-Term Neuroprotective Effects
Published 2020-01-01“…Accumulating evidence has demonstrated that immune memory occurs in microglia, which has a significant impact on pathological hallmarks of neurological diseases. However, it remains unclear whether immune memory can cause subsequent alterations in the brain immune response and affect neurobehavioral outcomes in sepsis survivors. …”
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147
The Benefits and Detriments of Macrophages/Microglia in Models of Multiple Sclerosis
Published 2013-01-01“…The central nervous system (CNS) is immune privileged with access to leukocytes being limited. In several neurological diseases, however, infiltration of immune cells from the periphery into the CNS is largely observed and accounts for the increased representation of macrophages within the CNS. …”
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148
Mitigating bias in AI mortality predictions for minority populations: a transfer learning approach
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149
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150
VisionMD: an open-source tool for video-based analysis of motor function in movement disorders
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151
Advances in neuromodulation for treatment of prolonged disorders of consciousness
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152
E3 ubiquitin ligase SYVN1 as a promising therapeutic target for diverse human diseases
Published 2025-02-01“…Consequently, SYVN1 plays a crucial role in both normal human physiology and the pathogenesis of various diseases, such as oncogenesis, cardiovascular disorders, immune regulation, skeletal anomalies, and neurological diseases. This review synthesizes recent findings regarding the physiological and pathophysiological roles of SYVN1, offering new insights into potential strategies for the prevention and treatment of human diseases, as well as suggesting avenues for future drug development. …”
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153
Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation
Published 2013-01-01“…During pregnancy, the previous responses promoted by viral infections and other proinflammatory conditions are common and might predispose the offspring to develop psychiatric disorders and neurological diseases. Such disorders could eventually be potentiated by stress and might be part of the etiopathogenesis of CNS dysfunctions including autism spectrum disorders and schizophrenia.…”
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154
A Comprehensive Review of Celecoxib Oral Solution for the Acute Treatment of Migraine
Published 2022-04-01“…A migraine is a clinical diagnosis with a presentation of one or more severe unilateral or bilateral headache(s) often preceded by an aura and typically accompanied by nausea, vomiting, photophobia, and/or phonophobia. This neurological disease is often debilitating and greatly affects the quality of life of those it inflicts. …”
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155
Cerebral Responses to Acupuncture at GV24 and Bilateral GB13 in Rat Models of Alzheimer’s Disease
Published 2018-01-01“…Acupuncture has been widely used in China to treat neurological diseases including Alzheimer’s disease (AD). …”
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156
Cyclin-Dependent Kinase-Like 5 (CDKL5): Possible Cellular Signalling Targets and Involvement in CDKL5 Deficiency Disorder
Published 2020-01-01“…We also discuss the relationship between changes in the phosphorylation signalling pathways and the Cdkl5 knockout mouse phenotype and consider future prospects for the treatment of mental and neurological disease associated with CDKL5 mutations.…”
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157
Modified ‘Xingnao Kaiqiao’ acupuncture technique shortens the recovery time of comatose patients
Published 2025-12-01“…Background This study was conducted to analyse the therapeutic effect of the modified ‘Xingnao Kaiqiao’ acupuncture technique in the recovery of comatose patients, as well as the clinical factors that may influence recovery from coma.Methods Diagnostic and therapeutic data from 166 patients in a coma due to neurological diseases were retrospectively collected. Eighty-seven comatose patients received conventional treatment, and 79 patients received conventional treatment + the modified ‘Xingnao Kaiqiao’ acupuncture technique. …”
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158
Therapeutic Use of Botulinum Toxin in Neurorehabilitation
Published 2012-01-01“…The use of BTX for the rehabilitation of children with obstetrical brachial plexus palsy and in treating sialorrhea which can complicate the course of some severe neurological diseases such as amyotrophic lateral sclerosis and Parkinson's disease is also addressed. …”
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159
Neurotropic Tick-Borne Flavivirus in Alpine Chamois (<i>Rupicapra rupicapra rupicapra</i>), Austria, 2017, Italy, 2023
Published 2025-01-01“…The European subtype of tick-borne encephalitis virus (TBEV-Eur; species <i>Orthoflavivirus encephalitidis</i>, family <i>Flaviviridae</i>) was the only tick-borne flavivirus present in central Europe known to cause neurologic disease in humans and several animal species. …”
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160
Exploring the microbiota-gut-brain axis: impact on brain structure and function
Published 2025-02-01“…By gaining a deeper understanding of the MGBA, it may be possible to facilitate research into microbial-based pharmacological interventions and therapeutic strategies for neurological diseases.…”
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