Gamisoyo-San Ameliorates Neuroinflammation in the Spinal Cord of hSOD1G93A Transgenic Mice by MuDan Cai, Eun Jin Yang

“…Moreover, we found that GSS inhibits the expression of proteins related to Toll-like receptor 4 signaling and oxidative stress, known to cause neuroinflammation. Notably, GSS also regulates metabolism in the spinal cord of transgenic mice. …”
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Effect of metformin on the neuronal morphology of frontal cortex and hippocampal regions in lipopolysaccharide induced neuroinflammation in male Wistar rats by Vandana Blossom, Sheetal D. Ullal, Rajalakshmi Rai, Amit Massand, Chettiar Ganesh Kumar, Teresa Joy, Melisha Michael D souza, B.V. Murlimanju

“…Background: Neuroinflammation in the frontal cortex and hippocampus is the key contributor in the pathogenesis of neurodegenerative diseases. …”
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Neuroinflammation in Parkinson's Disease and Related Disorders: A Lesson from Genetically Manipulated Mouse Models of α-Synucleinopathies by Kazunari Sekiyama, Shuei Sugama, Masayo Fujita, Akio Sekigawa, Yoshiki Takamatsu, Masaaki Waragai, Takato Takenouchi, Makoto Hashimoto

“…Neuroinflammation in Parkinson's disease (PD) is a chronic process that is associated with alteration of glial cells, including astrocytes and microglia. …”
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Activation of Wnt/β-catenin in neural progenitor cells regulates blood–brain barrier development and promotes neuroinflammation by Dylan J. Sebo, Irshad Ali, Audrey R. Fetsko, Aubrey A. Trimbach, Michael R. Taylor

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Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis by Shumin Zhao, Shumin Zhao, Ranran Chen, Ranran Chen, Yi An, Yali Zhang, Yali Zhang, Cheng Ma, Ying Gao, Ying Gao, Yanchao Lu, Yanchao Lu, Fei Yang, Fei Yang, Xue Bai, Xue Bai, Jingjing Zhang, Jingjing Zhang, Jingjing Zhang

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Investigation of Novel Aronia Bioactive Fraction-Alginic Acid Nanocomplex on the Enhanced Modulation of Neuroinflammation and Inhibition of Aβ Aggregation by Bong-Keun Jang, Soo Jung Shin, Hyun Ha Park, Vijay Kumar, Yong Ho Park, Jeom-Yong Kim, Hye-Yeon Kang, Sunyoung Park, Youngsun Kwon, Sang-Eun Shin, Minho Moon, Beom-Jin Lee

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Oleuropein Improves Cognitive Dysfunction and Neuroinflammation in Diabetic Rats through the PI3K/Akt/mTOR Pathway by Jianru Shang, Shan Che, Mingjie Zhu

“…Oleuropein ameliorates cognitive dysfunction and neuroinflammation in diabetic rats by regulating the PI3K/Akt/mTOR signaling pathway.…”
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A Network Pharmacology Study and Experimental Validation to Identify the Potential Mechanism of Heparan Sulfate on Alzheimer’s Disease-Related Neuroinflammation by Dong-Uk Kim, Bitna Kweon, Jinyoung Oh, Yebin Lim, Gyeongran Noh, Jihyun Yu, Hyang-Rin Kang, Tackmin Kwon, Kwang youll Lee, Gi-Sang Bae

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Brain-Specific Increase in Leukotriene Signaling Accompanies Chronic Neuroinflammation and Cognitive Impairment in a Model of Gulf War Illness by Sahithi Attaluri, Raghavendra Upadhya, Maheedhar Kodali, Leelavathi N. Madhu, Dinesh Upadhya, Bing Shuai, Ashok K. Shetty

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Genistein Protects against Spinal Cord Injury in Mice by Inhibiting Neuroinflammation via TLR4-Mediated Microglial Polarization by Xin-Wu Li, Peng Wu, Jian Yao, Kai Zhang, Gen-Yang Jin

“…Our findings suggested that genistein exerted neuroprotective action by inhibiting neuroinflammation by promoting the activation of M2 macrophages, and its underlying mechanisms might be related to the inhibition of the TLR4-mediated MyD88-dependent signaling pathway.…”
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Inhibition of S100A8/A9 ameliorates neuroinflammation by blocking NET formation following traumatic brain injury by Guihong Shi, Yiyao Cao, Jianye Xu, Bo Chen, Xu Zhang, Yanlin Zhu, Liang Liu, Xilei Liu, Luyuan Zhang, Yuan Zhou, Shenghui Li, Guili Yang, Xiao Liu, Fanglian Chen, Xin Chen, Jianning Zhang, Shu Zhang

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Cilostazol Combats Lipopolysaccharide-Induced Hippocampal Injury in Rats: Role of AKT/GSK3β/CREB Curbing Neuroinflammation by Doaa Abou El-ezz, Waleed Aldahmash, Tuba Esatbeyoglu, Sherif M. Afifi, Marawan Abd Elbaset

“…Neuroinflammation is important in the pathophysiology of several degenerative brain disorders. …”
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Effect of pasak bumi (Eurycoma longifolia Jack), DHA, and seluang fish (Rasbora spp.) on neuroinflammation and neurotransmitter alterations in malnourished rats by Triawanti, Didik Dwi Sanyoto, Meitria Syahadatina Noor, Dimas Ikhsan Airlangga

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Umbilical Cord Mesenchymal Stem Cells Overexpressing Heme Oxygenase-1 Promotes Symptoms Recovery in Cystitis Rats by Alleviating Neuroinflammation by Qiongqiong Gao, Zhentao Gao, Minzhi Su, Yong Huang, Chi Zhang, Cuiping Li, Hailun Zhan, Bolong Liu, Xiangfu Zhou

“…In the spinal dorsal horn (SDH), neuroinflammation plays a pivotal role in the development of IC. …”
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Corrigendum: Brain-specific increase in leukotriene signaling accompanies chronic neuroinflammation and cognitive impairment in a model of Gulf War Illness by Sahithi Attaluri, Raghavendra Upadhya, Maheedhar Kodali, Leelavathi N. Madhu, Dinesh Upadhya, Bing Shuai, Ashok K. Shetty

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Cannabidiol Modulates Neuroinflammatory and Estrogen-Related Pathways in a Sex-Specific Manner in a Chronic Stress Model of Depression by Uri Bright, Irit Akirav

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An enriched environment promotes cognitive recovery and cerebral blood flow in aged mice under sevoflurane anaesthesia by Wenfeng Gao, Wenji Xie, Wenqin Xie, Changcheng Jiang, Zhenming Kang, Naizhen Liu

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Cerebral microvascular density, blood-brain barrier permeability, and support for neuroinflammation indicate early aging in a Marfan syndrome mouse model by Tala Curry-Koski, Tala Curry-Koski, Liam P. Curtin, Mitra Esfandiarei, Mitra Esfandiarei, Mitra Esfandiarei, Theresa Currier Thomas, Theresa Currier Thomas, Theresa Currier Thomas, Theresa Currier Thomas

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Midkine Is a Novel Regulator of Amphetamine-Induced Striatal Gliosis and Cognitive Impairment: Evidence for a Stimulus-Dependent Regulation of Neuroinflammation by Midkine by Marta Vicente-Rodríguez, Rosalía Fernández-Calle, Esther Gramage, Carmen Pérez-García, María P. Ramos, Gonzalo Herradón

“…The data demonstrate for the first time that MK is a novel modulator of neuroinflammation depending on the inflammatory stimulus and the brain area considered. …”
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Targeting Cytokine-Mediated Inflammation in Brain Disorders: Developing New Treatment Strategies by Rahul Mallick, Sanjay Basak, Premanjali Chowdhury, Prasenjit Bhowmik, Ranjit K. Das, Antara Banerjee, Sujay Paul, Surajit Pathak, Asim K. Duttaroy

Subjects: “…cytokine-mediated neuroinflammation…”
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