Risk Factors for Infection Associated with Ischemic Stroke in Patients over 60 Years of Age by Alexis Suárez Quesada, Alexis Álvarez Aliaga, Andrés José Quesada Vázquez, Eduardo René Valdés Ramos, Ezequiel Ernesto López Espinosa

“…<br /><strong>Conclusions:</strong> the severity of ischemic stroke, the coexistence of neurodegenerative diseases and dysphagia constitute the main risk factors for infection associated with ischemic stroke in patients over 60 years of age.…”
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Impact of glycolysis inhibitor (2-DG) and oxidation and phosphorylation uncoupler (2,4-DNP) on brain metabolites by O. B. Shevelev, M. P. Moshkin

“…A deficiency of available energy for brain cells under neurodegenerative diseases is either developed due to age-dependent underexpression of genes that encode glycolytic enzymes or induced due to the uncoupling of oxidation and phosphorylation that could be mediated by inflammatory cytokines. …”
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Magnetic resonance imaging in primates. The example of the mouse lemur (Microcebus murinus): From detection of pathological aging to therapeutic evaluations by Nelly Joseph-Mathurin, Olene Dorieux, Audrey Kraska, Anne Bertrand, Mathieu Santin, Nadine El Tannir El Tayara, Marc Dhenain

“…It leads in many cases to neurodegenerative diseases such as Alzheimer disease (AD). Rodents and particularly transgenic mice are widely used as models for research on physiopathology of cerebral aging, neurodegenerative diseases and for the evaluation of therapies. …”
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Programmed neurite degeneration in human central nervous system neurons driven by changes in NAD+ metabolism by Markus Brüll, Selina Multrus, Michael Schäfer, Ivana Celardo, Christiaan Karreman, Marcel Leist

“…Abstract Neurite degeneration (ND) precedes cell death in many neurodegenerative diseases. However, it remains unclear how this compartmentalized cell death process is orchestrated in the central nervous system (CNS). …”
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Preclinical use of a clinically-relevant scAAV9/SUMF1 vector for the treatment of multiple sulfatase deficiency by Maximiliano Presa, Rachel M. Bailey, Somdatta Ray, Lauren Bailey, Saurabh Tata, Tara Murphy, Pierre-Alexandre Piec, Harold Combs, Steven J. Gray, Cathleen Lutz

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Application of antisense oligonucleotide drugs in amyotrophic lateral sclerosis and Huntington’s disease by Kaili Ou, Qingqing Jia, Dandan Li, Shihua Li, Xiao-Jiang Li, Peng Yin

“…Currently, available treatments for various neurodegenerative diseases can alleviate symptoms but do not provide a definitive cure. …”
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Epigenetic and Neurological Impairments Associated with Early Life Exposure to Persistent Organic Pollutants by Nathalie Grova, Henri Schroeder, Jean-Luc Olivier, Jonathan D. Turner

“…The incidence of neurodevelopmental and neurodegenerative diseases worldwide has dramatically increased over the last decades. …”
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Emerging role of gut microbiota extracellular vesicle in neurodegenerative disorders and insights on their therapeutic management by Adil Hassan, Yin Huang, Mahjabina, Otmilda Hapsari Sudiro, Xiangxiu Wang, Jingqin He, Yan Wei, Xiaoling Liao, Guixue Wang

“…Vesicle components contact immune receptors, initiating neuroinflammatory immune responses and causing neurodegenerative diseases. This study seeks to explain how the gut microbiota and its extracellular vesicles cause or worsen neurodegenerative diseases. …”
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A Review of the Effects of Physical Activity and Exercise on Cognitive and Brain Functions in Older Adults by Louis Bherer, Kirk I. Erickson, Teresa Liu-Ambrose

“…Together these finding suggest that physical exercise is a promising nonpharmaceutical intervention to prevent age-related cognitive decline and neurodegenerative diseases.…”
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Protective effects of wogonin in the treatment of central nervous system and degenerative diseases by Qingan Fu, Qingyun Yu, Hongdan Luo, Zhekang Liu, Xiaowei Ma, Huijian Wang, Zhijuan Cheng

“…Moreover, wogonin shows promise in treating neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease by promoting autophagy and reducing neuroinflammation. …”
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CHRONOTYPE AND DAILY FUNCTIONING OF PATIENTS WITH DIFFERENT MOTOR SUBTYPES OF PARKINSON DISEASE by A.D. Shkodina, M. Bardhan, K.A. Tarianyk, M. Yu. Delva

“…We conducted clinical research on the basis of the Centre for Parkinson Disease and Neurodegenerative Diseases of the Department of Neurological Diseases of Poltava State Medical University. …”
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Anti-Neuroinflammatory Effects of Prenylated Indole Alkaloids from the Antarctic Fungus <i>Aspergillus</i> sp. Strain SF-7367 by Zhiming Liu, Chi-Su Yoon, Thao Quyen Cao, Hwan Lee, Il-Chan Kim, Joung Han Yim, Jae Hak Sohn, Dong-Sung Lee, Hyuncheol Oh

“…Inflammation has always been considered a trigger or consequence of neurodegenerative diseases, and the inhibition of inflammation in the central nervous system can effectively protect nerve cells. …”
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Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications by Pharaoh Fellow Mwale, Cheng-Ta Hsieh, Ting-Lin Yen, Jing-Shiun Jan, Rajeev Taliyan, Chih-Hao Yang, Wen-Bin Yang

“…This review addresses the complexities of targeting CHI3L1, highlights its potential in precision medicine, and outlines future research directions aimed at unlocking its full therapeutic potential in treating neurodegenerative diseases and brain pathologies.…”
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Deep learning based tractography with TractSeg in patients with hemispherotomy: Evaluation and refinement by Johannes Gruen, Tobias Bauer, Theodor Rüber, Thomas Schultz

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An Overview of DNA Repair in Amyotrophic Lateral Sclerosis by Fabio Coppedè

“…Moreover, biochemical and genetic data on DNA repair in ALS are discussed in light of similar findings in other neurodegenerative diseases.…”
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Neuroinflammatory Mechanisms of Mitochondrial Dysfunction and Neurodegeneration in Glaucoma by Joao N. Duarte

“…Mitochondrial damage-associated molecular patterns (DAMPs) resulting from mitochondrial dysfunction have been linked to Leber’s hereditary optic neuropathy and autosomal dominant optic atrophy, as well as to brain neurodegenerative diseases. Recent evidence shows that, in conditions where mitochondria are damaged, a sustained inflammatory response and downstream pathological inflammation may ensue. …”
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Innate Immunity and Neuroinflammation by Abhishek Shastri, Domenico Marco Bonifati, Uday Kishore

“…Neuroinflammation occurs in close relation to trauma, infection, and neurodegenerative diseases. Low-level neuroinflammation is considered to have beneficial effects whereas chronic neuroinflammation can be harmful. …”
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Illuminating the impact of N-terminal acetylation: from protein to physiology by Nina McTiernan, Ine Kjosås, Thomas Arnesen

“…At the organismal level, N-terminal acetylation is highly influential, and its impairment was recently linked to cardiac dysfunction and neurodegenerative diseases.…”
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Levodopa Responsive Parkinsonism in Patients with Hemochromatosis: Case Presentation and Literature Review by Tarun Girotra, Abhimanyu Mahajan, Christos Sidiropoulos

“…Accumulation of iron in the brain has been postulated to be associated with several neurodegenerative diseases including Parkinson’s disease. The excess iron promotes Parkin and α-synuclein aggregation in the neurons. …”
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Frontotemporal dementia: peculiarities of clinical variants by B. Klimbytė, A. Vaitkus

“… Frontotemporal dementia (FTD) is a group of neurodegenerative diseases that cause atrophy of the frontal and temporal lobes of the brain. …”
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