Showing 121 - 140 results of 662 for search '"neurodegenerative diseases"', query time: 0.07s Refine Results
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    Human iPSC-derived microglial cells protect neurons from neurodegeneration in long-term cultured adhesion brain organoids by Xianwei Chen, Guoqiang Sun, Lizhao Feng, E Tian, Yanhong Shi

    Published 2025-01-01
    “…Therefore, the microglia-containing LT-ABO platform generated in this study provides a promising human cellular model for studying neuron-glia and glia-glia interactions in brain development and the pathogenesis of neurodegenerative diseases such as Alzheimer’s disease.…”
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  14. 134

    VCP regulates early tau seed amplification via specific cofactors by Sushobhna Batra, Jaime Vaquer-Alicea, Clarissa Valdez, Skyler P. Taylor, Victor A. Manon, Anthony R. Vega, Omar M. Kashmer, Sourav Kolay, Andrew Lemoff, Nigel J. Cairns, Charles L. White, Marc I. Diamond

    Published 2025-01-01
    “…VCP harbors dominant mutations that underlie two neurodegenerative diseases, multisystem proteinopathy and vacuolar tauopathy, but its mechanistic role is unclear. …”
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