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621
Daily Assistance for Amyotrophic Lateral Sclerosis Patients Based on a Wearable Multimodal Brain-Computer Interface Mouse
Published 2025-01-01“…Amyotrophic lateral sclerosis (ALS) is a chronic, progressive neurodegenerative disease that mainly causes damage to upper and lower motor neurons. …”
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622
Depression and Associated Factors Among Patients with Spinocerebellar Ataxia
Published 2025-01-01“…<i>Background and Objectives:</i> Spinocerebellar ataxia (SCA) is a progressive neurodegenerative disease often accompanied by depression. …”
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623
Improvement of Blood Plasmalogens and Clinical Symptoms in Parkinson’s Disease by Oral Administration of Ether Phospholipids: A Preliminary Report
Published 2020-01-01“…Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer’s disease (AD). With the ageing of population, the frequency of PD is expected to increase dramatically in the coming decades. …”
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624
The inhibition of ORMDL3 prevents Alzheimer's disease through ferroptosis by PERK/ATF4/HSPA5 pathway
Published 2023-05-01“…Abstract Alzheimer's disease (AD) is a neurodegenerative disease with high incidence and widespread attention. …”
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625
Neuroprotective Effect of the Combination of Citicoline and CoQ10 in a Mouse Model of Ocular Hypertension
Published 2024-12-01“…Glaucoma is a neurodegenerative disease characterized by the loss of retinal ganglion cells (RGCs), with intraocular pressure (IOP) being its primary risk factor. …”
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626
The Binding of BF-227-Like Benzoxazoles to Human α-Synuclein and Amyloid β Peptide Fibrils
Published 2018-09-01“…Development of an α-synuclein (α-Syn) positron emission tomography agent for the diagnosis and evaluation of Parkinson disease therapy is a key goal of neurodegenerative disease research. BF-227 has been described as an α-Syn binder and hence was employed as a lead to generate a library of α-Syn-binding compounds. [ 3 H]BF-227 bound to α-Syn and amyloid β peptide (Aβ) fibrils with affinities (K D ) of 46.0 nM and 15.7 nM, respectively. …”
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627
Advances in Stem Cell Therapy for Huntington’s Disease: A Comprehensive Literature Review
Published 2025-01-01“…Huntington’s disease (HD) is an inherited neurodegenerative disease characterized by uncontrolled movements, emotional disturbances, and progressive cognitive impairment. …”
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628
An overlap-weighted analysis on the association of constipation symptoms with disease progression and survival in amyotrophic lateral sclerosis: a nested case-control study
Published 2025-01-01“…Background: Amyotrophic lateral sclerosis (ALS) is a rapidly progressing and rare neurodegenerative disease. Therefore, evaluating the risk factors affecting the survival of patients with ALS is crucial. …”
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629
Akinetopsia: a systematic review on visual motion blindness
Published 2025-02-01“…Aetiologically, most cases were associated with structural neurological conditions such as stroke and neurodegenerative disease, and fewer with intoxications or paroxysmal neurological disorders such as epilepsy. …”
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630
Pharmacophore-based virtual screening for identification of marine sponge bioactive compound inhibitors against Alzheimer's disease
Published 2025-06-01“…Alzheimer's disease is a hereditary neurodegenerative disease that occurs sporadically and causes amnestic cognitive impairment. …”
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631
In vivo mapping of sodium homeostasis disturbances in individual ALS patients: A brain 23Na MRI study.
Published 2025-01-01“…<h4>Objective</h4>Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by significant heterogeneity among patients. 23Na MRI maps abnormal sodium homeostasis that reflects metabolic alterations and energetic failure contributing to the neurodegenerative process. …”
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632
Identifying the NEAT1/miR-26b-5p/S100A2 axis as a regulator in Parkinson's disease based on the ferroptosis-related genes.
Published 2024-01-01“…<h4>Objectives</h4>Parkinson's disease (PD) is a complex neurodegenerative disease with unclear pathogenesis. Some recent studies have shown that there is a close relationship between PD and ferroptosis. …”
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633
Extensive In Silico Analysis of ATL1 Gene : Discovered Five Mutations That May Cause Hereditary Spastic Paraplegia Type 3A
Published 2020-01-01“…Hereditary spastic paraplegia type 3A (SPG3A) is a neurodegenerative disease inherited type of Hereditary spastic paraplegia (HSP). …”
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634
Data Clustering Improves Siamese Neural Networks Classification of Parkinson’s Disease
Published 2021-01-01“…Parkinson’s disease (PD) is a clinical neurodegenerative disease having symptoms like tremor, rigidity, and postural disability. …”
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635
Sexual dimorphism in the sheep corpus callosum using 3 tesla MRI
Published 2021-12-01“…<p> <b>Conclusion:</b> It is thought that the findings obtained from healthy sheep brains in this study can be used in neurodegenerative disease models created in sheep in neuroscience studies and experimental studies.…”
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636
Cognitive enhancing effect of an extract of Swertia chirata against memory impairment induced by aluminum chloride
Published 2025-03-01“…Background: The most advanced type of neurodegenerative disease, Alzheimer's disease (AD), significantly reduces cognitive performance. …”
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637
Early Electrophysiological Disintegration of Hippocampal Neural Networks in a Novel Locus Coeruleus Tau-Seeding Mouse Model of Alzheimer’s Disease
Published 2019-01-01“…Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized by loss of synapses and disrupted functional connectivity (FC) across different brain regions. …”
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638
Artificial intelligence empowered voice generation for amyotrophic lateral sclerosis patients
Published 2025-01-01“…Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that can result in a progressive loss of speech due to bulbar dysfunction, which can have significant negative impact on the patient’s mental well-being. …”
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639
Clinicogenetic characterization and response to disease-modifying therapies in spinal muscular atrophy: real-world experience from a reference center in Southern Brazil
Published 2025-01-01“…Objective: Spinal Muscular Atrophy linked to chromosome 5q (SMA) is an autosomal recessive neurodegenerative disease characterized by progressive proximal muscle atrophy and weakness. …”
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640
The potential of stem cell therapy in Multiple Sclerosis treatment: a review
Published 2023-12-01“…Multiple Sclerosis is an autoimmune and neurodegenerative disease of the central nervous system. There are currently 2.8 million people living with Multiple Sclerosis worldwide, including 9000 people in Ireland, with a prevalence of 193 per 100,000 people. …”
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