Procoagulant Phospholipids and Tissue Factor Activity in Cerebrospinal Fluid from Patients with Intracerebral Haemorrhage by Patrick Van Dreden, Guy Hue, Jean-François Dreyfus, Barry Woodhams, Marc Vasse

“…Thirty had suffered an ICH, and 51 other neurological diagnoses [12: ventricular drainage following brain surgery, 13: viral meningitis, 15: bacterial meningitis, and 11 a neurodegenerative disease (NDD)]. PPL was measured using a factor Xa-based coagulation assay and TFa by one home test. …”
Get full text

Synthesis and Evaluation of the Acetylcholinesterase Inhibitory Activities of Some Flavonoids Derived from Naringenin by The-Huan Tran, Thi-Thu-Hien Vo, Thi-Quynh-Nhi Vo, Thi-Cam-Nhung Cao, Thai-Son Tran

“…Alzheimer’s disease (AD) is an irreversible neurodegenerative disease that affects many older people adversely. …”
Get full text

Prodromal Parkinson’s disease and subsequent risk of Parkinson’s disease and mortality by Xiao Chen, Yaqi Li, Yun Shen, Michael A. Schwarzschild, Xiang Gao

Get full text

PROTEOMIC PROFILING OF BLOOD-BASED BIOMARKERS IN THE EARLY DETECTION OF ALZHEIMERS DISEASE by Syeda Uroosa Hashmi, Fahad Farooq Lasi

“…Alzheimer's disease is considered an incurable, irreversible, and progressive type of neurodegenerative disease, in which the symptoms of dementia become worse with time. …”
Get full text

Brain health in Norwegian female former top-level football players: a protocol for a longitudinal cohort study by Thor Einar Andersen, Roald Bahr, Emilie Isager Howe, Peter Filipcik, John Bjørneboe, Geir Selbaek, Sara Christina Dahlén, Stian Kirkerud Sandmo, Lena Bache-Mathisen, Einar August Høgestøl, Truls Straume-Næsheim, Lars T Westlye

“…Recent studies have identified an association between playing football at the top level and an elevated risk of cognitive impairment and neurodegenerative disease. However, these were conducted on men, and there is a knowledge gap regarding these risks in female athletes. …”
Get full text

Nicotinamide adenine dinucleotide supplementation fails to enhance anesthetic recovery in rodents by Candida L. Goodnough, July Montoya, Erica B. Cartusciello, Erin L. Floranda, Eric R. Gross

“…Depletion of NAD+ is associated with aging and neurodegenerative disease, prompting a growing interest in NAD+ supplementation. …”
Get full text

Temporal and spatial pattern of DNA damage in neurons following spinal cord Injury in mice by Elle EM Scheijen, Naomi Veeningen, Sam Duwé, Anna Ivanova, Jana Van Broeckhoven, Sven Hendrix, David M Wilson

“…Abstract Background Deficient DNA repair and excessive DNA damage contribute to neurodegenerative disease. However, the role of DNA damage and repair in spinal cord injury (SCI) is unclear. …”
Get full text

Novel method for classification of prion diseases by detecting PrPres signal patterns from formalin-fixed paraffin-embedded samples by Sachiko Koyama, Kaoru Yagita, Hideomi Hamasaki, Hideko Noguchi, Masahiro Shijo, Kosuke Matsuzono, Kei-Ichiro Takase, Keita Kai, Shin-Ichi Aishima, Kyoko Itoh, Toshiharu Ninomiya, Naokazu Sasagasako, Hiroyuki Honda

“…Prion disease is an infectious and fatal neurodegenerative disease. Western blotting (WB)-based identification of proteinase K (PK)-resistant prion protein (PrPres) is considered a definitive diagnosis of prion diseases. …”
Get full text

iPSC-Derived Retinal Pigment Epithelium Allografts Do Not Elicit Detrimental Effects in Rats: A Follow-Up Study by Peter D. Westenskow, Felicitas Bucher, Stephen Bravo, Toshihide Kurihara, Daniel Feitelberg, Liliana P. Paris, Edith Aguilar, Jonathan H. Lin, Martin Friedlander

“…Photoreceptors rely heavily on the RPE, and death or dysfunction of RPE is characteristic of age-related macular degeneration (AMD), a very common neurodegenerative disease for which no cure exists. RPE replacement is a promising therapeutic intervention for AMD, and large numbers of RPE cells can be generated from pluripotent stem cells. …”
Get full text

Brown Adipose Tissue undergoes pathological perturbations and shapes C2C12 myoblast homeostasis in the SOD1-G93A mouse model of Amyotrophic Lateral Sclerosis by Marco Rosina, Silvia Scaricamazza, Flaminia Riggio, Gianmarco Fenili, Flavia Giannessi, Alessandro Matteocci, Valentina Nesci, Illari Salvatori, Daniela F. Angelini, Katia Aquilano, Valerio Chiurchiù, Daniele Lettieri Barbato, Nicola Biagio Mercuri, Cristiana Valle, Alberto Ferri

“…Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by the selective loss of motor neurons. …”
Get full text

A robust Parkinson’s disease detection model based on time-varying synaptic efficacy function in spiking neural network by Priya Das, Sarita Nanda, Ganapati Panda, Sujata Dash, Amel Ksibi, Shrooq Alsenan, Wided Bouchelligua, Saurav Mallik

“…Abstract Parkinson’s disease (PD) is a neurodegenerative disease affecting millions of people around the world. …”
Get full text

Antiparkinsonian activity of selective MAO-B inhibitors of different chemical structures by Vladimir N. Fedorov, Mikhail K. Korsakov, Anton A. Shetnev, Sergey S. Petukhov, Nikita N. Volkhin, Vladimir P. Vdovichenko, Anastasia A. Khokhlova, Salavat Sh. Suleymanov

“…Introduction: Parkinson’s disease (PD) is a chronic neurodegenerative disease of the central nervous system, the pathogenesis of which is associated with the death of dopaminergic neurons of the midbrain substantia nigra. …”
Get full text

Treatment with Herbal Formula Extract in the hSOD1G93A Mouse Model Attenuates Muscle and Spinal Cord Dysfunction via Anti-Inflammation by Eun Jin Yang, Sun Hwa Lee, Mudan Cai

“…Amyotrophic lateral sclerosis (ALS), a multicomplex neurodegenerative disease, has multiple underlying pathological factors and can induce other neuromuscular diseases, leading to muscle atrophy and respiratory failure. …”
Get full text

Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease. by Sydney R Coffey, Robert M Bragg, Shawn Minnig, Seth A Ament, Jeffrey P Cantle, Anne Glickenhaus, Daniel Shelnut, José M Carrillo, Dominic D Shuttleworth, Julie-Anne Rodier, Kimihiro Noguchi, C Frank Bennett, Nathan D Price, Holly B Kordasiewicz, Jeffrey B Carroll

“…Huntington's disease (HD) is an autosomal dominant neurodegenerative disease whose predominant neuropathological signature is the selective loss of medium spiny neurons in the striatum. …”
Get full text

Correction: Huntington Disease Health Related Quality of Life, Function and Well Being: The Patient’s Perspective by Jesús Pérez-Pérez, Sofía García-López, Tamara Fernández Valle, Cèlia Painous, Maria Rosa Querol-Pascual, Pedro J. García Ruiz, Elena Bellosta Diago, Esther Cubo Delgado, Barbara Vives Pastor, María Carmen Peiró Villaplana, Idaira Martín Santana, Marta Blázquez Estrada, Matilde Calopa Garride, Pablo Mir, Carmen Álvarez, Jorge Maurino, Anna de Prado, José Luis López-Sendón

Get full text

Can a Positive Allosteric Modulation of GABAergic Receptors Improve Motor Symptoms in Patients with Parkinson’s Disease? The Potential Role of Zolpidem in the Treatment of Parkinso... by Antonio Daniele, Francesco Panza, Antonio Greco, Giancarlo Logroscino, Davide Seripa

Get full text

Diagnostic Test to Identify Parkinson’s Disease from the Blood Sera of Chinese Population: A Cross-Sectional Study by Guangan Tong, Pingping Zhang, Wenbin Hu, Kun Zhang, Xianwen Chen

“…Parkinson’s disease (PD) is a neurodegenerative disease, a hallmark by the formation of misfolded and aggregated α-synuclein proteins. …”
Get full text

Oxidative stress and dysregulated long noncoding RNAs in the pathogenesis of Parkinson’s disease by Jialu Wang, Meitong Liu, Jiuhan Zhao, Pan Hu, Lianbo Gao, Shen Tian, Jin Zhang, Huayan Liu, Xiaoxue Xu, Zhenwei He

“…Abstract Parkinson’s disease (PD) is a progressive age-related neurodegenerative disease whose annual incidence is increasing as populations continue to age. …”
Get full text

The Role of Virtual Reality in Postural Rehabilitation for Patients with Parkinson’s Disease: A Scoping Review by Francesco Agostini, Marco Conti, Giovanni Morone, Giovanni Iudicelli, Andrea Fisicaro, Alessio Savina, Massimiliano Mangone, Marco Paoloni

“…Parkinson’s disease is the second most common neurodegenerative disease worldwide, characterized by bradykinesia, rigidity, tremor, and postural instability. …”
Get full text

Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis by Shumin Zhao, Shumin Zhao, Ranran Chen, Ranran Chen, Yi An, Yali Zhang, Yali Zhang, Cheng Ma, Ying Gao, Ying Gao, Yanchao Lu, Yanchao Lu, Fei Yang, Fei Yang, Xue Bai, Xue Bai, Jingjing Zhang, Jingjing Zhang, Jingjing Zhang

“…IntroductionAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of motor neurons (MNs). …”
Get full text