Live imaging of excitable axonal microdomains in ankyrin-G-GFP mice by Christian Thome, Jan Maximilian Janssen, Seda Karabulut, Claudio Acuna, Elisa D'Este, Stella J Soyka, Konrad Baum, Michael Bock, Nadja Lehmann, Johannes Roos, Nikolas A Stevens, Masashi Hasegawa, Dan A Ganea, Chloé M Benoit, Jan Gründemann, Lia Y Min, Kalynn M Bird, Christian Schultz, Vann Bennett, Paul M Jenkins, Maren Engelhardt

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Frontotemporal Dementia as a Possible Manifestation of Primary Lateral Sclerosis: A Case Report and Literature Review by Kevin Qosja, Nicole M. Absar, Allen T. Yu

“…Primary lateral sclerosis (PLS) is currently defined as a restricted phenotype of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease with upper motor neuron (UMN) symptoms that causes slowly progressive spasticity. …”
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Maximizing the Survival of Amyotrophic Lateral Sclerosis Patients: Current Perspectives by Osama A. Khairoalsindi, Ahmad R. Abuzinadah

“…Amyotrophic lateral sclerosis is a neurodegenerative disease that leads to loss of the upper and lower motor neurons. …”
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Machine learning identified novel players in lipid metabolism, endosomal trafficking, and iron metabolism of the ALS spinal cord by Jack Cheng, Bor-Tsang Wu, Hsin-Ping Liu, Wei-Yong Lin

“…Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting motor neurons. Although genes causing familial cases have been identified, those of sporadic ALS, which occupies the majority of patients, are still elusive. …”
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Role of neuroinflammation in the pathogenesis of glaucomatous optic neuropathy by E.A. Egorov, V.E. Korelina, D.V. Cherednichenko, I.R. Gazizova

“…POAG is now considered a neurodegenerative disease associated with neuroinflammation. …”
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Are oligodendrocytes bystanders or drivers of Parkinson's disease pathology? by José María Salazar Campos, Lena F Burbulla, Sarah Jäkel

“…The major pathological feature of Parkinson 's disease (PD), the second most common neurodegenerative disease and most common movement disorder, is the predominant degeneration of dopaminergic neurons in the substantia nigra, a part of the midbrain. …”
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Crocetin Alleviates Inflammation in MPTP-Induced Parkinson’s Disease Models through Improving Mitochondrial Functions by Na Dong, Zhong Dong, Ying Chen, Xiaosu Gu

“…Parkinson’s disease (PD) is the second most common neurodegenerative disease. Crocetin, derived from saffron, exerts multiple pharmacological properties, such as anti-inflammatory, antioxidant, antifatigue, and anticancer effects. …”
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Exercise Intervention Associated with Cognitive Improvement in Alzheimer’s Disease by Meng Ying Cui, Yang Lin, Ji Yao Sheng, Xuewen Zhang, Ran Ji Cui

“…Alzheimer’s disease (AD) is a progressive neurodegenerative disease with the syndrome of cognitive and functional decline. …”
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Mechanisms and active substances of targeting lipid peroxidation in ferroptosis regulation by Hui Chen, Lingli Chen, Wenjun Wang

“…Ferroptosis is a novel form of cell death driven by iron-dependent lipid peroxidation and it is implicated in various diseases, such as liver disease, acute kidney injury, cardiovascular disease, neurodegenerative disease and cancer. Lipid-based reactive oxygen species (ROS), particularly lipid hydroperoxides in the cellular membrane can lead to membrane disruption and cell death mediated by ferroptosis. …”
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Modeling sacsin depletion in Danio Rerio offers new insight on retinal defects in ARSACS by Valentina Naef, Devid Damiani, Rosario Licitra, Maria Marchese, Stefania Della Vecchia, Matteo Baggiani, Letizia Brogi, Daniele Galatolo, Silvia Landi, Filippo Maria Santorelli

“…Biallelic mutations in the SACS gene, encoding sacsin, cause early-onset autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disease also characterized by unique and poorly understood retinal abnormalities. …”
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Age-Related Macular Degeneration: Insights into Inflammatory Genes by Raffaella Cascella, Michele Ragazzo, Claudia Strafella, Filippo Missiroli, Paola Borgiani, Francesco Angelucci, Luigi Tonino Marsella, Andrea Cusumano, Giuseppe Novelli, Federico Ricci, Emiliano Giardina

“…Age-related macular degeneration (AMD) is a progressive neurodegenerative disease that affects approximately 8.7% of elderly people worldwide (>55 years old). …”
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Advancements in the Use of Hydrogels for Regenerative Medicine: Properties and Biomedical Applications by Andrea Revete, Andrea Aparicio, Bruno A. Cisterna, Javier Revete, Luis Luis, Ernesto Ibarra, Edwin A. Segura González, Jay Molino, Diego Reginensi

“…This reason presents them as an exciting alternative to highly complex human physiological problems, such as injuries to the central nervous system and neurodegenerative disease.…”
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Targeting MDM2 affects spastin protein levels and functions: implications for HSP treatment by Francesca Sardina, Federica Polverino, Sonia Valentini, Claudia Carsetti, Elisabetta Falvo, Giada Tisci, Silvia Soddu, Fabiola Moretti, Alessandro Paiardini, Cinzia Rinaldo

“…A reduction in spastin protein levels is responsible for approximately 40% of cases of Hereditary Spastic Paraplegia (HSP), a neurodegenerative disease. Currently, there is no cure for HSP but strategies to induce a recovery of spastin levels are emerging as potential therapeutic approaches. …”
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Catecholaminergic dysfunction drives postural and locomotor deficits in a mouse model of spinal muscular atrophy by John G. Pagiazitis, Nicolas Delestrée, Leonie Sowoidnich, Nandhini Sivakumar, Christian M. Simon, Athanasios Chatzisotiriou, Maria Albani, George Z. Mentis

“…Dopamine and noradrenaline strongly influence locomotion, and their dysregulation initiates the development of motor impairments linked to neurodegenerative disease. However, the precise cellular and circuit mechanisms are not well defined. …”
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Initial Immunopathogenesis of Multiple Sclerosis: Innate Immune Response by Norma Y. Hernández-Pedro, Guillermo Espinosa-Ramirez, Verónica Pérez de la Cruz, Benjamín Pineda, Julio Sotelo

“…Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease of the central nervous system. The hallmark to MS is the demyelinated plaque, which consists of a well-demarcated hypocellular area characterized by the loss of myelin, the formation of astrocytic scars, and the mononuclear cell infiltrates concentrated in perivascular spaces composed of T cells, B lymphocytes, plasma cells, and macrophages. …”
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SNP Analysis of the SOD1 gene involved in Amyotrophic Lateral Sclerosis (ALS) by Hetal Patel, Anandita Banerjee, Pritha Saha, Subramaniyan Divya, Palaniyandi Ravanan, Priti Talwar

“…ALS is a rare neurodegenerative disease causing the loss of motor neurons in the brain and spinal cord. …”
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Application of Low Intensity Ultrasound in the Treatment of Alzheimer’s Disease by Hong Fei, Xu Fei

“…Alzheimer’s disease (AD) is a common neurodegenerative disease in clinical practice. The pathogenesis is still unclear, and there is no specific method. …”
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Sodium Butyrate Protects N2a Cells against Aβ Toxicity In Vitro by Jingxuan Sun, Boyu Yuan, Yancheng Wu, Yuhong Gong, Wenjin Guo, Shoupeng Fu, Yongxin Luan, Wei Wang

“…Alzheimer’s disease (AD) is a common neurodegenerative disease. Aβ plays an important role in the pathogenesis of AD. …”
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Anesthesia Management in Scoliosis Surgery of Patients with Friedreich’s Ataxia: A Report of Four Cases by Muhammed Köse, Ercan Bal, Şemsi Mustafa Aksoy, Ayşe Lafçı

“…Friedreich's ataxia (FRDA) is an autosomal recessive neurodegenerative disease, which may be accompanied by scoliosis, cardiac, endocrine and pulmonary comorbidities. …”
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Psychosocial Adjustment of In-Home Caregivers of Family Members with Dementia and Parkinson’s Disease: A Comparative Study by María Cristina Lopes Dos Santos, María Victoria Navarta-Sánchez, José Antonio Moler, Ignacio García-Lautre, Sagrario Anaut-Bravo, Mari Carmen Portillo

“…Neurodegenerative diseases such as Parkinson’s and dementia are highly prevalent worldwide. …”
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