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421
Mechanisms of Neuroprotection by Protein Disulphide Isomerase in Amyotrophic Lateral Sclerosis
Published 2011-01-01“…Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterised by the progressive loss of motor neurons, leading to paralysis and death within several years of onset. …”
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422
Case report: Significant lesion reduction and neural structural changes following ibogaine treatments for multiple sclerosis
Published 2025-02-01“…Multiple sclerosis (MS) is a debilitating neurodegenerative disease characterized by demyelination and neuronal loss. …”
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423
Genetic Rat Models of Parkinson's Disease
Published 2012-01-01“…Parkinson’s disease (PD) is a neurodegenerative disease characterized by a specific loss of dopaminergic neurons. …”
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424
Frontotemporal Dementia as a Possible Manifestation of Primary Lateral Sclerosis: A Case Report and Literature Review
Published 2022-01-01“…Primary lateral sclerosis (PLS) is currently defined as a restricted phenotype of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease with upper motor neuron (UMN) symptoms that causes slowly progressive spasticity. …”
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425
Maximizing the Survival of Amyotrophic Lateral Sclerosis Patients: Current Perspectives
Published 2018-01-01“…Amyotrophic lateral sclerosis is a neurodegenerative disease that leads to loss of the upper and lower motor neurons. …”
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426
Crocetin Alleviates Inflammation in MPTP-Induced Parkinson’s Disease Models through Improving Mitochondrial Functions
Published 2020-01-01“…Parkinson’s disease (PD) is the second most common neurodegenerative disease. Crocetin, derived from saffron, exerts multiple pharmacological properties, such as anti-inflammatory, antioxidant, antifatigue, and anticancer effects. …”
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427
Exercise Intervention Associated with Cognitive Improvement in Alzheimer’s Disease
Published 2018-01-01“…Alzheimer’s disease (AD) is a progressive neurodegenerative disease with the syndrome of cognitive and functional decline. …”
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428
Modeling sacsin depletion in Danio Rerio offers new insight on retinal defects in ARSACS
Published 2025-02-01“…Biallelic mutations in the SACS gene, encoding sacsin, cause early-onset autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disease also characterized by unique and poorly understood retinal abnormalities. …”
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429
Age-Related Macular Degeneration: Insights into Inflammatory Genes
Published 2014-01-01“…Age-related macular degeneration (AMD) is a progressive neurodegenerative disease that affects approximately 8.7% of elderly people worldwide (>55 years old). …”
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430
Advancements in the Use of Hydrogels for Regenerative Medicine: Properties and Biomedical Applications
Published 2022-01-01“…This reason presents them as an exciting alternative to highly complex human physiological problems, such as injuries to the central nervous system and neurodegenerative disease.…”
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431
Targeting MDM2 affects spastin protein levels and functions: implications for HSP treatment
Published 2025-02-01“…A reduction in spastin protein levels is responsible for approximately 40% of cases of Hereditary Spastic Paraplegia (HSP), a neurodegenerative disease. Currently, there is no cure for HSP but strategies to induce a recovery of spastin levels are emerging as potential therapeutic approaches. …”
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432
Initial Immunopathogenesis of Multiple Sclerosis: Innate Immune Response
Published 2013-01-01“…Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease of the central nervous system. The hallmark to MS is the demyelinated plaque, which consists of a well-demarcated hypocellular area characterized by the loss of myelin, the formation of astrocytic scars, and the mononuclear cell infiltrates concentrated in perivascular spaces composed of T cells, B lymphocytes, plasma cells, and macrophages. …”
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433
SNP Analysis of the SOD1 gene involved in Amyotrophic Lateral Sclerosis (ALS)
Published 2025-12-01“…ALS is a rare neurodegenerative disease causing the loss of motor neurons in the brain and spinal cord. …”
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434
Application of Low Intensity Ultrasound in the Treatment of Alzheimer’s Disease
Published 2025-03-01“…Alzheimer’s disease (AD) is a common neurodegenerative disease in clinical practice. The pathogenesis is still unclear, and there is no specific method. …”
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435
Sodium Butyrate Protects N2a Cells against Aβ Toxicity In Vitro
Published 2020-01-01“…Alzheimer’s disease (AD) is a common neurodegenerative disease. Aβ plays an important role in the pathogenesis of AD. …”
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436
Psychosocial Adjustment of In-Home Caregivers of Family Members with Dementia and Parkinson’s Disease: A Comparative Study
Published 2020-01-01“…Neurodegenerative diseases such as Parkinson’s and dementia are highly prevalent worldwide. …”
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437
Toll-Like Receptor 4: A Promising Therapeutic Target for Alzheimer’s Disease
Published 2022-01-01“…Alzheimer’s disease (AD) is a progressive neurodegenerative disease that primarily manifests as memory deficits and cognitive impairment and has created health challenges for patients and society. …”
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438
Application of Three-Dimensional (3D) Printing in Neurosurgery
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439
Pediatric Multiple Sclerosis and Cognition: A Review of Clinical, Neuropsychologic, and Neuroradiologic Features
Published 2017-01-01“…Multiple sclerosis (MS) is an inflammatory demyelinating and neurodegenerative disease. Although cognitive impairment has been well established in adult patients with MS, its occurrence in patients with pediatric-onset MS has recently been reported. …”
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440
A case report of fatal familial insomnia with cerebrospinal fluid leukocytosis during the COVID-19 epidemic and review of the literature
Published 2024-12-01“…Fatal familial insomnia (FFI) is a rare autosomal dominant genetic neurodegenerative disease. Generally, FFI patients will develop rapidly progressive dementia, sleep disturbance, autonomic dysfunction, and so on. …”
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