Showing 421 - 440 results of 510 for search '"neurodegenerative diseases"', query time: 0.09s Refine Results
  1. 421

    Mechanisms of Neuroprotection by Protein Disulphide Isomerase in Amyotrophic Lateral Sclerosis by Adam K. Walker, Julie D. Atkin

    Published 2011-01-01
    “…Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterised by the progressive loss of motor neurons, leading to paralysis and death within several years of onset. …”
    Get full text
    Article
  2. 422
  3. 423

    Genetic Rat Models of Parkinson's Disease by Ryan M. Welchko, Xavier T. Lévêque, Gary L. Dunbar

    Published 2012-01-01
    “…Parkinson’s disease (PD) is a neurodegenerative disease characterized by a specific loss of dopaminergic neurons. …”
    Get full text
    Article
  4. 424

    Frontotemporal Dementia as a Possible Manifestation of Primary Lateral Sclerosis: A Case Report and Literature Review by Kevin Qosja, Nicole M. Absar, Allen T. Yu

    Published 2022-01-01
    “…Primary lateral sclerosis (PLS) is currently defined as a restricted phenotype of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease with upper motor neuron (UMN) symptoms that causes slowly progressive spasticity. …”
    Get full text
    Article
  5. 425

    Maximizing the Survival of Amyotrophic Lateral Sclerosis Patients: Current Perspectives by Osama A. Khairoalsindi, Ahmad R. Abuzinadah

    Published 2018-01-01
    “…Amyotrophic lateral sclerosis is a neurodegenerative disease that leads to loss of the upper and lower motor neurons. …”
    Get full text
    Article
  6. 426

    Crocetin Alleviates Inflammation in MPTP-Induced Parkinson’s Disease Models through Improving Mitochondrial Functions by Na Dong, Zhong Dong, Ying Chen, Xiaosu Gu

    Published 2020-01-01
    “…Parkinson’s disease (PD) is the second most common neurodegenerative disease. Crocetin, derived from saffron, exerts multiple pharmacological properties, such as anti-inflammatory, antioxidant, antifatigue, and anticancer effects. …”
    Get full text
    Article
  7. 427

    Exercise Intervention Associated with Cognitive Improvement in Alzheimer’s Disease by Meng Ying Cui, Yang Lin, Ji Yao Sheng, Xuewen Zhang, Ran Ji Cui

    Published 2018-01-01
    “…Alzheimer’s disease (AD) is a progressive neurodegenerative disease with the syndrome of cognitive and functional decline. …”
    Get full text
    Article
  8. 428

    Modeling sacsin depletion in Danio Rerio offers new insight on retinal defects in ARSACS by Valentina Naef, Devid Damiani, Rosario Licitra, Maria Marchese, Stefania Della Vecchia, Matteo Baggiani, Letizia Brogi, Daniele Galatolo, Silvia Landi, Filippo Maria Santorelli

    Published 2025-02-01
    “…Biallelic mutations in the SACS gene, encoding sacsin, cause early-onset autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disease also characterized by unique and poorly understood retinal abnormalities. …”
    Get full text
    Article
  9. 429

    Age-Related Macular Degeneration: Insights into Inflammatory Genes by Raffaella Cascella, Michele Ragazzo, Claudia Strafella, Filippo Missiroli, Paola Borgiani, Francesco Angelucci, Luigi Tonino Marsella, Andrea Cusumano, Giuseppe Novelli, Federico Ricci, Emiliano Giardina

    Published 2014-01-01
    “…Age-related macular degeneration (AMD) is a progressive neurodegenerative disease that affects approximately 8.7% of elderly people worldwide (>55 years old). …”
    Get full text
    Article
  10. 430

    Advancements in the Use of Hydrogels for Regenerative Medicine: Properties and Biomedical Applications by Andrea Revete, Andrea Aparicio, Bruno A. Cisterna, Javier Revete, Luis Luis, Ernesto Ibarra, Edwin A. Segura González, Jay Molino, Diego Reginensi

    Published 2022-01-01
    “…This reason presents them as an exciting alternative to highly complex human physiological problems, such as injuries to the central nervous system and neurodegenerative disease.…”
    Get full text
    Article
  11. 431

    Targeting MDM2 affects spastin protein levels and functions: implications for HSP treatment by Francesca Sardina, Federica Polverino, Sonia Valentini, Claudia Carsetti, Elisabetta Falvo, Giada Tisci, Silvia Soddu, Fabiola Moretti, Alessandro Paiardini, Cinzia Rinaldo

    Published 2025-02-01
    “…A reduction in spastin protein levels is responsible for approximately 40% of cases of Hereditary Spastic Paraplegia (HSP), a neurodegenerative disease. Currently, there is no cure for HSP but strategies to induce a recovery of spastin levels are emerging as potential therapeutic approaches. …”
    Get full text
    Article
  12. 432

    Initial Immunopathogenesis of Multiple Sclerosis: Innate Immune Response by Norma Y. Hernández-Pedro, Guillermo Espinosa-Ramirez, Verónica Pérez de la Cruz, Benjamín Pineda, Julio Sotelo

    Published 2013-01-01
    “…Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease of the central nervous system. The hallmark to MS is the demyelinated plaque, which consists of a well-demarcated hypocellular area characterized by the loss of myelin, the formation of astrocytic scars, and the mononuclear cell infiltrates concentrated in perivascular spaces composed of T cells, B lymphocytes, plasma cells, and macrophages. …”
    Get full text
    Article
  13. 433

    SNP Analysis of the SOD1 gene involved in Amyotrophic Lateral Sclerosis (ALS) by Hetal Patel, Anandita Banerjee, Pritha Saha, Subramaniyan Divya, Palaniyandi Ravanan, Priti Talwar

    Published 2025-12-01
    “…ALS is a rare neurodegenerative disease causing the loss of motor neurons in the brain and spinal cord. …”
    Get full text
    Article
  14. 434

    Application of Low Intensity Ultrasound in the Treatment of Alzheimer’s Disease by Hong Fei, Xu Fei

    Published 2025-03-01
    “…Alzheimer’s disease (AD) is a common neurodegenerative disease in clinical practice. The pathogenesis is still unclear, and there is no specific method. …”
    Get full text
    Article
  15. 435

    Sodium Butyrate Protects N2a Cells against Aβ Toxicity In Vitro by Jingxuan Sun, Boyu Yuan, Yancheng Wu, Yuhong Gong, Wenjin Guo, Shoupeng Fu, Yongxin Luan, Wei Wang

    Published 2020-01-01
    “…Alzheimer’s disease (AD) is a common neurodegenerative disease. Aβ plays an important role in the pathogenesis of AD. …”
    Get full text
    Article
  16. 436
  17. 437

    Toll-Like Receptor 4: A Promising Therapeutic Target for Alzheimer’s Disease by Linyu Wu, Xiaohui Xian, Guangyu Xu, Zixuan Tan, Fang Dong, Min Zhang, Feng Zhang

    Published 2022-01-01
    “…Alzheimer’s disease (AD) is a progressive neurodegenerative disease that primarily manifests as memory deficits and cognitive impairment and has created health challenges for patients and society. …”
    Get full text
    Article
  18. 438
  19. 439

    Pediatric Multiple Sclerosis and Cognition: A Review of Clinical, Neuropsychologic, and Neuroradiologic Features by Ozgul Ekmekci

    Published 2017-01-01
    “…Multiple sclerosis (MS) is an inflammatory demyelinating and neurodegenerative disease. Although cognitive impairment has been well established in adult patients with MS, its occurrence in patients with pediatric-onset MS has recently been reported. …”
    Get full text
    Article
  20. 440

    A case report of fatal familial insomnia with cerebrospinal fluid leukocytosis during the COVID-19 epidemic and review of the literature by Zheng Wang, Yueqi Huang, Shuqi Wang, Jiefang Chen, Gesang Meiduo, Man Jin, Xiaoying Zhang

    Published 2024-12-01
    “…Fatal familial insomnia (FFI) is a rare autosomal dominant genetic neurodegenerative disease. Generally, FFI patients will develop rapidly progressive dementia, sleep disturbance, autonomic dysfunction, and so on. …”
    Get full text
    Article