Neural Induction, Neural Fate Stabilization, and Neural Stem Cells by Sally A. Moody, Hyun-Soo Je

“…The promise of stem cell therapy is expected to greatly benefit the treatment of neurodegenerative diseases. An underlying biological reason for the progressive functional losses associated with these diseases is the extremely low natural rate of self-repair in the nervous system. …”
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Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity by Gabriel Olmos, Jerònia Lladó

“…This review summarizes the current knowledge of the cellular and molecular mechanisms by which TNF-α links the neuroinflammatory and excitotoxic processes that occur in several neurodegenerative diseases, but with a special emphasis on amyotrophic lateral sclerosis (ALS). …”
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The role of smell in medical and psychological disorders: An interdisciplinary approach by Giuseppe Riva

“…Finally, central causes of smell alterations result from the damage of the olfactory processing pathways of the central nervous system, such as neurodegenerative diseases [1]. Olfactory testing includes subjective, psychophysical, and objective evaluations [4]. …”

Targeted ErbB4 receptor activation prevents D-galactose-induced neuronal senescence via inhibiting ferroptosis pathway by Ji-Ji Dao, Ji-Ji Dao, Wei Zhang, Wei Zhang, Chong Liu, Chong Liu, Qian Li, Qian Li, Chen-Meng Qiao, Chen-Meng Qiao, Chun Cui, Chun Cui, Yan-Qin Shen, Yan-Qin Shen, Shuang-Xi Chen, Shuang-Xi Chen, Wei-Jiang Zhao, Wei-Jiang Zhao

“…BackgroundNeuronal senescence is a common pathological feature of various neurodegenerative diseases, with ferroptosis playing a significant role. …”
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Therapeutic potential of cannabinoids in neurological conditions: a systematic review of clinical trials by Alqassem Y. Hakami, Alqassem Y. Hakami, Fahad S. Alshehri

“…OverviewCannabinoids have gained increasing attention for their therapeutic potential in treating several neurological conditions, including neurodegenerative diseases, chronic pain, and epilepsy. This review aims to assess the current clinical trials investigating cannabinoids, primarily Tetrahydrocannabinol and Cannabidiol, for neurological disorders. …”
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Brain Magnetic Resonance Imaging Findings in Developmentally Delayed Children by Ali Akbar Momen, Gholamreza Jelodar, Hamid Dehdashti

“…The finding includes nonspecific in 38 (6.6%), congenital and developmental anomalies of brain in 39 (6.7%), recognizable syndromes in 3 (0.5%), neurovascular diseases or trauma in 218 (37.6%), and metabolic or neurodegenerative diseases in 42 (7.2%) cases. Conclusion. Because 60% of all study groups showed abnormal brain MRI, using this method could be effective in diagnosis, management, and almost prognosis determination processes.…”
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The Role of Air Pollution and Olfactory Dysfunction in Alzheimer’s Disease Pathogenesis by Louise Odendaal, Hazel Quek, Carla Cuní-López, Anthony R. White, Romal Stewart

“…The focus of recent research has shifted towards understanding its potential association with neurodegenerative diseases, specifically Alzheimer’s disease (AD). …”
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Inherited Paediatric Motor Neuron Disorders: Beyond Spinal Muscular Atrophy by Hooi Ling Teoh, Kate Carey, Hugo Sampaio, David Mowat, Tony Roscioli, Michelle Farrar

“…Paediatric motor neuron diseases encompass a group of neurodegenerative diseases characterised by the onset of muscle weakness and atrophy before the age of 18 years, attributable to motor neuron loss across various neuronal networks in the brain and spinal cord. …”
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Targeting Mitochondrial Dysfunction in Cerebral Ischemia: Advances in Pharmacological Interventions by Igor Belenichev, Olena Popazova, Nina Bukhtiyarova, Victor Ryzhenko, Sergii Pavlov, Elina Suprun, Valentyn Oksenych, Oleksandr Kamyshnyi

“…This article highlights the critical role of mitochondrial dysfunction in the progression of neurodegenerative diseases and discusses the need for targeted therapeutic strategies to attenuate cellular damage, restore mitochondrial function, and enhance neuroprotection.…”
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Therapeutic targeting of obesity-induced neuroinflammation and neurodegeneration by Jialiu Zeng, Jialiu Zeng, Lenny Yi Tong Cheong, Chih Hung Lo, Chih Hung Lo

“…These disruptions impair normal neuronal function and subsequently lead to cognitive decline and motor deficits, similar to the pathologies observed in major neurodegenerative diseases, including Alzheimer’s disease, multiple sclerosis, and Parkinson’s disease. …”
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Overexpression of SFPQ Improves Cognition and Memory in AD Mice by Jinshan Tie, Hongxiang Wu, Wei Liu, Yuying Li, Lu Li, Suju Zhao, Zhijiao Yuan, Khan Mahmood, Shaochun Chen, Huidong Wu

“…Splicing factor proline and glutamine rich (SFPQ) is known to play a crucial role in neurodegenerative diseases, including antioxidant-related functions and regulating gene expression within brain neurons. …”
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Impact of Time Delay in Perceptual Decision-Making: Neuronal Population Modeling Approach by Urszula Foryś, Natalia Z. Bielczyk, Katarzyna Piskała, Martyna Płomecka, Jan Poleszczuk

“…Impairments in decision-making are frequently observed in neurodegenerative diseases, but the mechanisms underlying such pathologies remain elusive. …”
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A hypothesis about interrelations of epigenetic factors and transposable elements in memory formation by R. N. Mustafin

“…Pathological activation of transposable elements is a likely cause of neurodegenerative diseases with memory impairment. Analysis of the scientific literature allowed us to identify changes in the expression of 40 microRNAs derived from transposons in Alzheimer’s disease. …”
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Antibody-mediated degradation of 4R-tau restores mitochondrial membrane polarization in human induced pluripotent stem cell-derived neurons with the MAPT 10+16 mutation by Dale O. Starkie, Charles Arber, Terry Baker, Daniel J. Lightwood, Selina Wray

“…Microtubule-associated protein tau is inextricably linked to a group of clinically diverse neurodegenerative diseases termed tauopathies. The ratio balance of the major tau splicing isoform groups (3 R- and 4 R-tau) is critical in maintaining healthy neurons. …”
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MRI-guided focused ultrasound for treating Parkinson’s disease with human mesenchymal stem cells by Sheng-Kai Wu, Chia-Lin Tsai, Aisha Mir, Kullervo Hynynen

“…Mesenchymal stem cell therapy may be a viable treatment option for neurodegenerative diseases such as Parkinson’s. Transcranial MRgFUS serves as an efficacious and safe method for targeted and minimally invasive stem cell homing.…”
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Dental Mesenchymal Stem/Stromal Cells and Their Exosomes by Peter Stanko, Ursula Altanerova, Jana Jakubechova, Vanda Repiska, Cestmir Altaner

“…The therapeutic applicability of these cells and exosomes in dental practice, neurodegenerative diseases, and many other difficultly treatable diseases, like myocardial infarction, focal cerebral ischemia, acute lung or brain injury, acute respiratory distress syndrome, acute inflammation, and several others is concisely covered. …”
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Analyzing the potential of neuronal pentraxin 2 as a biomarker in neurological disorders: A literature review by Ubaid Ansari, Jimmy Wen, Burhaan Syed, Dawnica Nadora, Romteen Sedighi, Denise Nadora, Vincent Chen, Forshing Lui

“…Emerging research suggests that NP2 is implicated in the pathogenesis of various neurological disorders, including neurodegenerative diseases, neuropsychiatric disorders, and neuropathies. …”
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The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease by Kemal Ugur Tufekci, Ezgi Civi Bayin, Sermin Genc, Kursad Genc

“…Mitochondrial dysfunction is a prominent feature of various neurodegenerative diseases as strict regulation of integrated mitochondrial functions is essential for neuronal signaling, plasticity, and transmitter release. …”
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The Efficiency of Direct Maturation: the Comparison of Two hiPSC Differentiation Approaches into Motor Neurons by Catherine Schaefers, Simone Rothmiller, Horst Thiermann, Theo Rein, Annette Schmidt

“…Motor neurons (MNs) derived from human-induced pluripotent stem cells (hiPSC) hold great potential for the treatment of various motor neurodegenerative diseases as transplantations with a low-risk of rejection are made possible. …”
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Identifying natural inhibitors against FUS protein in dementia through machine learning, molecular docking, and dynamics simulation by Darwin Li

“…Dementia, a complex and debilitating spectrum of neurodegenerative diseases, presents a profound challenge in the quest for effective treatments. …”
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