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241
Neuropsychiatric symptoms in Alzheimer’s disease
Published 2024-02-01“…Alzheimer’s disease is one of the most common neurodegenerative diseases among older people that manifests as deterioration of cognitive functions, impaired daily activities, and progressive degeneration of cerebral cortex neurons. …”
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242
Non-invasive brain stimulation in cognitive sciences and Alzheimer's disease
Published 2025-01-01“…In the present paper, basic physiological and technical mechanisms and different applications of NIBS were reviewed and discussed to highlight the importance of NIBS in multidisciplinary and translational approaches in clinical and research settings of cognitive sciences and neurodegenerative diseases, especially in Alzheimer's disease. …”
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243
Neuroprotection Caused by Hyperoxia Preconditioning in Animal Stroke Models
Published 2011-01-01“…Ischemic tolerance induced by hyperoxia (HO) can protect against brain injury and neurodegenerative diseases. Although multiple studies demonstrate neuroprotection by HO, the exact mechanism(s) of HO neuroprotection has not been elucidated. …”
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244
Relationship between enriched environment and neurodegeneration: a review from mechanism to therapy
Published 2025-01-01“…Abstract Enriched environment (EE), as a non-pharmacological intervention, has garnered considerable attention for its potential to ameliorate neurodegenerative diseases (NDs). This review delineated the impact of EE on the biological functions associated with NDs, emphasizing its role in enhancing neural plasticity, reducing inflammation, and bolstering cognitive performance. …”
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245
Acid-Sensing Ion Channels as Potential Therapeutic Targets in Neurodegeneration and Neuroinflammation
Published 2017-01-01“…This review focuses on recent advances that have helped us to better understand the role played by ASICs in different pathologies related to neurodegenerative diseases, inflammatory processes, and pain.…”
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246
Role of Neuroinflammation in Adult Neurogenesis and Alzheimer Disease: Therapeutic Approaches
Published 2013-01-01“…Neuroinflammation, a specialized immune response that takes place in the central nervous system, has been linked to neurodegenerative diseases, and specially, it has been considered as a hallmark of Alzheimer disease, the most common cause of dementia in the elderly nowadays. …”
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247
Generating Diverse Spinal Motor Neuron Subtypes from Human Pluripotent Stem Cells
Published 2016-01-01“…Motor neurons (MNs) represent a diverse pool of neuronal subtypes exhibiting differential vulnerability in different human neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA). …”
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248
Improvement of in Vivo Quantification of [I]-Iodobenzovesamicol in Single-Photon Emission Computed Tomography/Computed Tomography Using Anatomic Image to Brain Atlas Nonrigid Regis...
Published 2013-07-01“…Brain anatomy variability is a major problem in quantifying functional images in nuclear medicine, in particular relative to aging and neurodegenerative diseases. The aim of this study was to compare affine and elastic model–based methods for magnetic resonance imaging (MRI) to brain atlas registration and to assess their impact on the quantification of cholinergic neurotransmission. …”
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249
Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects
Published 2022-01-01“…Many new metal-based drugs were developed from the metal complexes which are potentially active against a number of ailments such as cancer, malaria, and neurodegenerative diseases. Therefore, this review is an attempt to describe the present scenario and future development of metal complexes as antibiotics against wide array of microbes.…”
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250
Exploring the Impact of Brain-Computer Interfaces on Health Care: Innovations, Challenges, and Future Prospects: A Review Article
Published 2024-12-01“…We describe trends in the development of BCIs from simple experimental paradigms to multimedia advanced devices and their usage in clinical practice: assistive technology in patients with motor disorders, neurorehabilitation of post-stroke patients, and cognitive prosthesis for humans with neurodegenerative diseases. The article also emphasizes on present-day issues including signal quality, comfort level of the users, and the ethical parameter of the technique along with the research going on and future work streams. …”
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251
3D-QSAR, design, molecular docking and dynamics simulation studies of novel 6-hydroxybenzothiazole-2-carboxamides as potentially potent and selective monoamine oxidase B inhibitors
Published 2025-01-01“…The successfully designed compound 31.j3 not only demonstrated efficient inhibitory activity, but also verified its stable binding to MAO-B receptor by MD simulation, which provides strong support for the development of novel therapeutic drugs for neurodegenerative diseases. These findings provide important theoretical basis and practical guidance for future drug design and experimental validation.…”
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252
A Dynamic Adaptive Ensemble Learning Framework for Noninvasive Mild Cognitive Impairment Detection: Development and Validation Study
Published 2025-01-01“… BackgroundThe prompt and accurate identification of mild cognitive impairment (MCI) is crucial for preventing its progression into more severe neurodegenerative diseases. However, current diagnostic solutions, such as biomarkers and cognitive screening tests, prove costly, time-consuming, and invasive, hindering patient compliance and the accessibility of these tests. …”
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253
Assessment of clinical prognosis in autoimmune encephalitis: Girona score
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254
Distinct patterns of prion strain deposition and toxicity in a novel whole brain organotypic slice culture system
Published 2025-02-01“…Abstract Prion diseases are fatal transmissible neurodegenerative diseases that affect many mammals, including humans, caused by the templated misfolding of the prion protein. …”
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255
Recent Advances of the NLRP3 Inflammasome in Central Nervous System Disorders
Published 2016-01-01“…In addition, we summarize the recent researches on the role of NLRP3 inflammasome in central nervous system (CNS) diseases, including traumatic brain injury, ischemic stroke and hemorrhagic stroke, brain tumor, neurodegenerative diseases, and other CNS diseases. In conclusion, the NLRP3 inflammasome may be a promising therapeutic target for these CNS diseases.…”
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256
Insulin in Central Nervous System: More than Just a Peripheral Hormone
Published 2012-01-01“…Insulin signaling in central nervous system (CNS) has emerged as a novel field of research since decreased brain insulin levels and/or signaling were associated to impaired learning, memory, and age-related neurodegenerative diseases. Thus, besides its well-known role in longevity, insulin may constitute a promising therapy against diabetes- and age-related neurodegenerative disorders. …”
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257
The Brain’s Aging Resting State Functional Connectivity
Published 2025-01-01“…By providing an overview of the current state of knowledge in this field, this review aims to guide future research endeavors aimed at promoting healthy brain aging and developing effective interventions for age-related cognitive impairment and neurodegenerative diseases.…”
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258
Cookware as source of toxic metals: An overview
Published 2024-10-01“…Aluminum used in cookware, has raised health concerns because of its possible associations with neurodegenerative diseases. Metal leaching is influenced by various factors, including acidity, cooking duration, and temperature. …”
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259
Insight into the Molecular Imaging of Alzheimer’s Disease
Published 2016-01-01“…Alzheimer’s disease is a complex neurodegenerative disease affecting millions of individuals worldwide. …”
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260
Astrocyte-Secreted Matricellular Proteins in CNS Remodelling during Development and Disease
Published 2014-01-01“…Conversely, their reexpression in reactive astrocytes may also lead to detrimental effects and promote the progression of neurodegenerative diseases.…”
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