Anti-Neuroinflammatory Effects of Prenylated Indole Alkaloids from the Antarctic Fungus <i>Aspergillus</i> sp. Strain SF-7367 by Zhiming Liu, Chi-Su Yoon, Thao Quyen Cao, Hwan Lee, Il-Chan Kim, Joung Han Yim, Jae Hak Sohn, Dong-Sung Lee, Hyuncheol Oh

“…Inflammation has always been considered a trigger or consequence of neurodegenerative diseases, and the inhibition of inflammation in the central nervous system can effectively protect nerve cells. …”
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Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications by Pharaoh Fellow Mwale, Cheng-Ta Hsieh, Ting-Lin Yen, Jing-Shiun Jan, Rajeev Taliyan, Chih-Hao Yang, Wen-Bin Yang

“…This review addresses the complexities of targeting CHI3L1, highlights its potential in precision medicine, and outlines future research directions aimed at unlocking its full therapeutic potential in treating neurodegenerative diseases and brain pathologies.…”
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Deep learning based tractography with TractSeg in patients with hemispherotomy: Evaluation and refinement by Johannes Gruen, Tobias Bauer, Theodor Rüber, Thomas Schultz

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An Overview of DNA Repair in Amyotrophic Lateral Sclerosis by Fabio Coppedè

“…Moreover, biochemical and genetic data on DNA repair in ALS are discussed in light of similar findings in other neurodegenerative diseases.…”
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Neuroinflammatory Mechanisms of Mitochondrial Dysfunction and Neurodegeneration in Glaucoma by Joao N. Duarte

“…Mitochondrial damage-associated molecular patterns (DAMPs) resulting from mitochondrial dysfunction have been linked to Leber’s hereditary optic neuropathy and autosomal dominant optic atrophy, as well as to brain neurodegenerative diseases. Recent evidence shows that, in conditions where mitochondria are damaged, a sustained inflammatory response and downstream pathological inflammation may ensue. …”
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Innate Immunity and Neuroinflammation by Abhishek Shastri, Domenico Marco Bonifati, Uday Kishore

“…Neuroinflammation occurs in close relation to trauma, infection, and neurodegenerative diseases. Low-level neuroinflammation is considered to have beneficial effects whereas chronic neuroinflammation can be harmful. …”
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Illuminating the impact of N-terminal acetylation: from protein to physiology by Nina McTiernan, Ine Kjosås, Thomas Arnesen

“…At the organismal level, N-terminal acetylation is highly influential, and its impairment was recently linked to cardiac dysfunction and neurodegenerative diseases.…”
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Levodopa Responsive Parkinsonism in Patients with Hemochromatosis: Case Presentation and Literature Review by Tarun Girotra, Abhimanyu Mahajan, Christos Sidiropoulos

“…Accumulation of iron in the brain has been postulated to be associated with several neurodegenerative diseases including Parkinson’s disease. The excess iron promotes Parkin and α-synuclein aggregation in the neurons. …”
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Frontotemporal dementia: peculiarities of clinical variants by B. Klimbytė, A. Vaitkus

“… Frontotemporal dementia (FTD) is a group of neurodegenerative diseases that cause atrophy of the frontal and temporal lobes of the brain. …”
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The Genetics of Parkinson’s Disease by Levent Şimşek, Emine Berrin Yüksel, Zeliha Yücel

“…Parkinson's disease (PD) is one of the most common neurodegenerative diseases worldwide. Approximately 15% of PD patients have a family history of the disease in one or more first-degree relatives, and 5-10% of PD cases exhibit a classical Mendelian inheritance pattern. …”
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Configuration of health pathway networks for patients with chronic diseases by Laaziz El Hassan

“…Chronic and long-term diseases, particularly neurodegenerative diseases and polymorbidity, are increasingly occupying the medical and socio-medical landscape and are a concern for government policies. …”
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Sympathetic Prions by Markus Glatzel

“…Transmissible spongiform encephalopathies are a group of invariably fatal neurodegenerative diseases. The infectious agent is termed prion and is thought to be composed of a modified protein (PrPSc or PrPRES), a protease-resistant conformer of the normal host-encoded membrane glycoprotein, PrPC[1]. …”
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Cardiac and respiratory activities induce temporal changes in cerebral blood volume, balanced by a mirror CSF volume displacement in the spinal canal by Pan Liu, Kimi Owashi, Heimiri Monnier, Serge Metanbou, Cyrille Capel, Olivier Balédent

“…Understanding cerebrospinal fluid (CSF) dynamics is crucial for elucidating the pathogenesis and diagnosis of neurodegenerative diseases. The primary mechanisms driving CSF oscillations remain a topic of debate. …”
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Timing of risk factors, prodromal features, and comorbidities of dementia from a large health claims case–control study by Stefan Teipel, Manas Akmatov, Bernhard Michalowsky, Steffi Riedel-Heller, Jens Bohlken, Jakob Holstiege

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Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer’s Disease by Giuseppe Verdile, Kevin N. Keane, Vinicius F. Cruzat, Sandra Medic, Miheer Sabale, Joanne Rowles, Nadeeja Wijesekara, Ralph N. Martins, Paul E. Fraser, Philip Newsholme

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Xixin Decoction’s novel mechanism for alleviating Alzheimer’s disease cognitive dysfunction by modulating amyloid-β transport across the blood–brain barrier to reduce neuroinflamma... by Chaokai Yang, Enlong Zhao, Hu Zhang, Liqi Duan, Xinyue Han, Hongli Ding, Yan Cheng, Dengkun Wang, Dengkun Wang, Dengkun Wang, Xiaojing Lei, Xiaojing Lei, Xiaojing Lei, Yongchang Diwu, Yongchang Diwu, Yongchang Diwu

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Interaction between 𝛼-Synuclein and Other Proteins in Neurodegenerative Disorders by Kurt A. Jellinger

“…Inclusions, characteristics of these disorders, also occurring in other neurodegenerative diseases, suggest interactions of pathological proteins engaging common downstream pathways. …”
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Oxidative stress: an overview of past research and future insights by Aaser M. Abdelazim, Mosleh M. Abomughaid

“…The obtained findings suggest that many diseases are linked to OS, including diabetes mellitusinflammation, cancers, autoimmune disorders and neurodegenerative diseases. More recently, significant advances in biochemistry and molecular biology have enabled researchers to find master switches of various OS mechanisms and associate OS development to many biological paradigms. …”
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Editorial: Animal models of Alzheimer's disease and other dementias: past, present, and future by Ines Moreno-Gonzalez, Ines Moreno-Gonzalez, Ines Moreno-Gonzalez, Jesus Garcia-Martin, Roberta Marongiu, Roberta Marongiu, Roberta Marongiu

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Melatonin as a powerful antioxidant by Chrustek Agnieszka, Olszewska-Słonina Dorota

“…There is a relationship between failure in melatonin production in the pineal gland, an insufficient supply of this hormone to the body, and the occurrence of free radical etiology diseases such as neurodegenerative diseases, cardiovascular diseases, diabetes, cancer and others. …”
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