Identifying natural inhibitors against FUS protein in dementia through machine learning, molecular docking, and dynamics simulation by Darwin Li

“…Dementia, a complex and debilitating spectrum of neurodegenerative diseases, presents a profound challenge in the quest for effective treatments. …”
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Acute β-N-Methylamino-L-alanine Toxicity in a Mouse Model by Maitham Ahmed Al-Sammak, Douglas G. Rogers, Kyle D. Hoagland

“…Long-term exposure to L-BMAA is believed to lead to neurodegenerative diseases including Parkinson’s and Alzheimer’s diseases and amyotrophic lateral sclerosis (Lou Gehrig’s disease). …”
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Unveiling the biological effects of radio-frequency and extremely-low frequency electromagnetic fields on the central nervous system performance by Ramin Eskandani, Mohammad Ismail Zibaii

“…ELF-EMF exposure has been associated with the enhancement of CNS performance, marked by improved memory retention, enhanced learning ability, and potential mitigation of neurodegenerative diseases. Nevertheless, it is essential to acknowledge that ELF-EMF exposure has also been linked to the induction of anxiety states, oxidative stress, and alterations in hormonal regulation. …”
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Impact of Aluminium Chloride (AlCl₃) on Brain Function: A Review of Neurotoxic Mechanisms and Implications for Alzheimer's Disease by Amtul Rahman, Zeenath Banu

“…This review emphasizes the need for further research into AlCl3's neurotoxic mechanisms to clarify its role in AD and other neurodegenerative diseases. Enhanced understanding may help develop preventive measures and regulations to mitigate the health risks posed by aluminium exposure in daily life.…”
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QSPR Analysis of Some Alzheimer’s Compounds via Topological Indices and Regression Models by Muhammad Shoaib Sardar, Khalil Hadi Hakami

“…Neurodegenerative diseases (NDDs) have received considerable interest from scientists for a long time due to their multifactorial nature. …”
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Association of cognitive reserve with stroke outcome: a protocol for a systematic review by Laura Gallucci, Roza M Umarova

“…Introduction The concept of cognitive reserve (CR) was introduced to account for individual differences in the clinical manifestation of neurodegenerative diseases. Though several mechanisms and risk factors are shared between neurodegeneration and stroke, the effect of CR on poststroke functional outcome has been poorly addressed. …”
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Nonpharmacological Modulation of Chronic Inflammation in Parkinson’s Disease: Role of Diet Interventions by Stefania Kalampokini, Anouck Becker, Klaus Fassbender, Epameinondas Lyros, Marcus M. Unger

“…Neuroinflammation is increasingly recognized as an important pathophysiological feature of neurodegenerative diseases such as Parkinson’s disease (PD). …”
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Association of Glycemic Indices (Hyperglycemia, Glucose Variability, and Hypoglycemia) with Oxidative Stress and Diabetic Complications by Eleftheria Papachristoforou, Vaia Lambadiari, Eirini Maratou, Konstantinos Makrilakis

“…Oxidative stress has been associated with a variety of pathologic conditions, including diabetes mellitus (DM), cancer, atherosclerosis, neurodegenerative diseases, rheumatoid arthritis, ischemia/reperfusion injury, obstructive sleep apnea, and accelerated aging. …”
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APOE4 and infectious diseases jointly contribute to brain glucose hypometabolism, a biomarker of Alzheimer's pathology: New findings from the ADNI. by Aravind Lathika Rajendrakumar, Konstantin G Arbeev, Olivia Bagley, Matt Duan, Anatoliy I Yashin, Svetlana Ukraintseva, Alzheimer’s Disease Neuroimaging Initiative

“…<h4>Background</h4>Impaired brain glucose metabolism is a preclinical feature of neurodegenerative diseases such as Alzheimer's disease (AD). …”
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Mast Cell Deficiency Protects Mice from Surgery-Induced Neuroinflammation by Xiang Zhang, Hongquan Dong, Fei Wang, Jun Zhang

“…Neuroinflammation plays a key role in the occurrence and development of neurodegenerative diseases. Microglia, the resident immune cells in the brain, have been recognized to contribute to neuroinflammation. …”
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Epidemiology and Risk Factors for Orthostatic Hypotension and Its Severity in Residents Aged > 60 years: A Cross-Sectional Study by Mingni Yang, Ruiqiang Peng, Zetuo Wang, Miaoduan Li, Yehua Song, Jianping Niu, Yong Ji

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The TRPV1-PKM2-SREBP1 axis maintains microglial lipid homeostasis in Alzheimer’s disease by Xudong Sha, Jiayuan Lin, Kexin Wu, Jia Lu, Zhihua Yu

“…Abstract Microglia are progressively activated by inflammation and exhibit phagocytic dysfunction in the pathogenesis of neurodegenerative diseases. Lipid-droplet-accumulating microglia were identified in the aging mouse and human brain; however, little is known about the formation and role of lipid droplets in microglial neuroinflammation of Alzheimer’s disease (AD). …”
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From data to diagnosis: leveraging deep learning in IoT-based healthcare by Miracle A. Atianashie, Chukwuma Chinaza Adaobi

“…Furthermore, the implementation of deep learning technologies in healthcare IoT has proven effective in the early detection of critical health conditions, including cancer and neurodegenerative diseases, through sophisticated analysis of medical images and physiological data. …”
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Effect of Lipopolysaccharide and TNFα on Neuronal Ascorbic Acid Uptake by Veedamali S. Subramanian, Trevor Teafatiller, Anshu Agrawal, Masashi Kitazawa, Jonathan S. Marchant

“…Elevated levels of LPS and TNFα have been associated with neurodegenerative diseases together with reduced levels of AA. …”
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Genetic approaches to the investigation of serotonergic neuron functions in animals by U. S. Drozd, E. V. Shaburova, N. N. Dygalo

“…The understanding of its mechanisms will help scientists create new therapeutic approaches to the treatment of mental and neurodegenerative diseases and find out how this neurotransmitter system interacts with other parts of the brain and regulates their activity. …”
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The role of the corticotropin-releasing hormone and its receptors in the regulation of stress response by E. V. Sukhareva

“…Disturbances of the CRH system regulation are directly related to such disorders: mental pathologies (depression, anxiety, addictions), deviations of neuroendocrinological functions, inflammation, as well as the onset and development of neurodegenerative diseases such as Alzheimer’s disease. In addition, the role of CRH as a regulator of the neurons structure in the areas of the developing and mature brain has been established. …”
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Cilostazol Combats Lipopolysaccharide-Induced Hippocampal Injury in Rats: Role of AKT/GSK3β/CREB Curbing Neuroinflammation by Doaa Abou El-ezz, Waleed Aldahmash, Tuba Esatbeyoglu, Sherif M. Afifi, Marawan Abd Elbaset

“…Cilostazol may hold promise as a therapeutic agent for neuroinflammatory conditions associated with neurodegenerative diseases.…”
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Impact of Implementing Structured Compensatory Methods on Knowledge and Awareness of Cognitive Dysfunction Management Among Neurological Disorder Patients in Vijayapur Hospitals by Nelson Vijaykumar, Aleyamma Varghese

“…It can result from neurotoxicity ischemia or neurodegenerative diseases like Alzheimerrsquos and Parkinsonrsquos.Objectives The study aimed to assess knowledge about cognitive impairment evaluate the effectiveness of structured compensatory techniques and analyze the relationship between knowledge scores and sociodemographic variables.Methodology The study assessed the effectiveness of structured compensatory techniques in improving knowledge about cognitive impairment among neurological patients in Vijayapura hospitals. …”
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Assessment and Management of Cognitive and Psychosocial Difficulties for People with Multiple Sclerosis in Ireland: A National Survey of Clinical Practice by Sinéad M. Hynes, Fiadhnait O’Keeffe, Eimear Bane, Megan H. Oglesby, Christopher P. Dwyer, Robert Joyce, Olga A. Klein

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Advances in chromosomal microarray analysis: Transforming neurology and neurosurgery by Wireko Andrew Awuah, Muhammad Hamza Shah, Vivek Sanker, Krishitha Meenu Mannan, Sruthi Ranganathan, Princess Afia Nkrumah-Boateng, Mabel Frimpong, Kwadwo Darko, Joecelyn Kirani Tan, Toufik Abdul-Rahman, Oday Atallah

“…CMA's clinical utility spans numerous neurological conditions, providing crucial insights into neurodevelopmental disorders, CNS tumours, neurodegenerative diseases, cerebrovascular diseases, and epilepsy. …”
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