Showing 1 - 20 results of 390 for search '"neurodegeneration"', query time: 0.04s Refine Results
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    Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease by Géraldine Gelders, Veerle Baekelandt, Anke Van der Perren

    Published 2018-01-01
    “…In this review, we address the current concept of neuroinflammation and its involvement in PD-associated neurodegeneration.…”
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    Article
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    Neuroinflammatory Mechanisms of Mitochondrial Dysfunction and Neurodegeneration in Glaucoma by Joao N. Duarte

    Published 2021-01-01
    “…The present review focuses on how mitochondrial dysfunction may overwhelm the ability of neurons and glial cells to adequately maintain homeostasis and how mitochondria-derived DAMPs trigger the immune system and induce neurodegeneration.…”
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    Article
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    Association of p53 with Neurodegeneration in Parkinson’s Disease by Qiang Luo, Wei Sun, Yi-Fan Wang, Ji Li, Da-Wei Li

    Published 2022-01-01
    “…We reviewed the current knowledge concerning p53-dependent neurodegeneration to better understand the underlying mechanisms and provide possible strategies for PD treatment by targeting p53.…”
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    Article
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    Deep Brain Stimulation for Pantothenate Kinase-Associated Neurodegeneration by Pedro J. Garcia-Ruiz, Joaquin Ayerbe, Lydia Vela Desojo, Cici E. Feliz, Javier del Val Fernandez

    Published 2015-01-01
    “…Pantothenate kinase-associated neurodegeneration (PKAN) is usually associated with dystonia, which is typically severe and progressive over time. …”
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    The effect of AKT inhibition in α-synuclein-dependent neurodegeneration by Bedri Ranxhi, Zoya R. Bangash, Zachary M. Chbihi, Sokol V. Todi, Sokol V. Todi, Peter A. LeWitt, Peter A. LeWitt, Peter A. LeWitt, Wei-Ling Tsou

    Published 2025-02-01
    “…However, in PD, α-Syn cumulatively misfolds into toxic aggregates that disrupt cellular processes and contribute to neuronal damage and neurodegeneration. Previous studies implicated the AKT signaling pathway in α-Syn toxicity in cellular models of PD, suggesting AKT as a potential therapeutic target. …”
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    Chemokines and Neurodegeneration in the Early Stage of Experimental Ischemic Stroke by Pawel Wolinski, Andrzej Glabinski

    Published 2013-01-01
    “…Neurodegeneration is a hallmark of most of the central nervous system (CNS) disorders including stroke. …”
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    RNA-Binding Proteins in Amyotrophic Lateral Sclerosis and Neurodegeneration by Scott E. Ugras, James Shorter

    Published 2012-01-01
    “…This study underscores the important role that perturbations in RNA metabolism might play in neurodegeneration, and it raises the possibility that future studies will identify other RBPs with critical roles in neurodegenerative disease.…”
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    Eye of the Tiger Sign in Pantothenate Kinase-Associated Neurodegeneration by S. Choayb, H. Adil, Daoud Ali Mohamed, N. Allali, L. Chat, S. El Haddad

    Published 2021-01-01
    “…Pantothenate kinase-associated neurodegeneration (PKAN) is a rare disorder associated with brain iron accumulation caused by a recessive mutation in pantothenate kinase 2 gene (PANK2). …”
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