Showing 161 - 180 results of 390 for search '"neurodegeneration"', query time: 0.05s Refine Results
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    The transcriptional response of cortical neurons to concussion reveals divergent fates after injury by Mor R. Alkaslasi, Eliza Y. H. Lloyd, Austin S. Gable, Hanna Silberberg, Hector E. Yarur, Valerie S. Tsai, Mira Sohn, Gennady Margolin, Hugo A. Tejeda, Claire E. Le Pichon

    Published 2025-01-01
    “…Abstract Traumatic brain injury (TBI) is a risk factor for neurodegeneration, however little is known about how this kind of injury alters neuron subtypes. …”
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    Estrogen-related receptor gamma is a regulator of mitochondrial, autophagy, and immediate-early gene programs in spiny projection neurons: Relevance for transcriptional changes in... by Stephanie N. Fox, Cody H. Savage, Narcy R. Amireddy, Laura J. McMeekin, David K. Crossman, Peter J. Detloff, Michelle Gray, Rita M. Cowell

    Published 2025-03-01
    “…To determine whether the alterations observed with ERRγ modulation have any relevance for understanding transcriptional changes in SPNs in neurodegeneration, we measured Esrrg and its responsive genes in two mouse models of HD. …”
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  10. 170

    The role of neurotrophic factors in retinal ganglion cell resiliency by Alan K. Abraham, Alan K. Abraham, Michael Telias, Michael Telias

    Published 2025-01-01
    “…Many retinal diseases are characterized by direct or indirect retinal ganglion cell (RGC) neurodegeneration. In glaucoma and optic nerve neuropathies, RGCs are the primary affected cells, whereas in photoreceptor dystrophies, RGC loss is secondary to the death of rods and cones. …”
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    Mechanisms of ubiquitin-independent proteasomal degradation and their roles in age-related neurodegenerative disease by Taylor R. Church, Seth S. Margolis, Seth S. Margolis

    Published 2025-02-01
    “…Because of this, most research on proteasomal roles in neurodegeneration has historically focused on the UPS. …”
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    Friends or Foes: Matrix Metalloproteinases and Their Multifaceted Roles in Neurodegenerative Diseases by Marjana Brkic, Sriram Balusu, Claude Libert, Roosmarijn E. Vandenbroucke

    Published 2015-01-01
    “…Neurodegeneration is a chronic progressive loss of neuronal cells leading to deterioration of central nervous system (CNS) functionality. …”
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    Therapeutic Actions of the Thiazolidinediones in Alzheimer’s Disease by María José Pérez, Rodrigo A. Quintanilla

    Published 2015-01-01
    “…However, in this review, we will discuss several cellular targets, in which TZDs can be acting against the neurodegeneration.…”
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  19. 179

    The Endotoxin-Induced Neuroinflammation Model of Parkinson's Disease by Kemal Ugur Tufekci, Sermin Genc, Kursad Genc

    Published 2011-01-01
    “…Although the exact cause of the dopaminergic neurodegeneration remains elusive, recent postmortem and experimental studies have revealed an essential role for neuroinflammation that is initiated and driven by activated microglial and infiltrated peripheral immune cells and their neurotoxic products (such as proinflammatory cytokines, reactive oxygen species, and nitric oxide) in the pathogenesis of PD. …”
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  20. 180

    Cox-2 Plays a Vital Role in the Impaired Anxiety Like Behavior in Colchicine Induced Rat Model of Alzheimer Disease by Susmita Sil, Tusharkanti Ghosh

    Published 2016-01-01
    “…The anxiety status is changed along with memory impairments in intracerebroventricular colchicine injected rat model of Alzheimer Disease (cAD) due to neurodegeneration, which has been indicated to be mediated by inflammation. …”
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