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Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis
Published 2025-01-01“…Molecular Neurodegeneration…”
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162
RNA-Targeting CRISPR/CasRx system relieves disease symptoms in Huntington’s disease models
Published 2025-01-01“…Molecular Neurodegeneration…”
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163
Genetic context modulates aging and degeneration in the murine retina
Published 2025-01-01“…Molecular Neurodegeneration…”
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164
Positron emission tomography tracers for synucleinopathies
Published 2025-01-01“…Molecular Neurodegeneration…”
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165
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The Role of Air Pollution and Olfactory Dysfunction in Alzheimer’s Disease Pathogenesis
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167
The transcriptional response of cortical neurons to concussion reveals divergent fates after injury
Published 2025-01-01“…Abstract Traumatic brain injury (TBI) is a risk factor for neurodegeneration, however little is known about how this kind of injury alters neuron subtypes. …”
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Estrogen-related receptor gamma is a regulator of mitochondrial, autophagy, and immediate-early gene programs in spiny projection neurons: Relevance for transcriptional changes in...
Published 2025-03-01“…To determine whether the alterations observed with ERRγ modulation have any relevance for understanding transcriptional changes in SPNs in neurodegeneration, we measured Esrrg and its responsive genes in two mouse models of HD. …”
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170
The role of neurotrophic factors in retinal ganglion cell resiliency
Published 2025-01-01“…Many retinal diseases are characterized by direct or indirect retinal ganglion cell (RGC) neurodegeneration. In glaucoma and optic nerve neuropathies, RGCs are the primary affected cells, whereas in photoreceptor dystrophies, RGC loss is secondary to the death of rods and cones. …”
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171
Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis
Published 2012-01-01Get full text
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172
Distinct subcellular localization of tau and alpha-synuclein in lewy body disease
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173
Mechanisms of ubiquitin-independent proteasomal degradation and their roles in age-related neurodegenerative disease
Published 2025-02-01“…Because of this, most research on proteasomal roles in neurodegeneration has historically focused on the UPS. …”
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174
MicroRNA-451a is a candidate biomarker and therapeutic target for major depressive disorder
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175
The ABC transporter A7 modulates neuroinflammation via NLRP3 inflammasome in Alzheimer’s disease mice
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176
Friends or Foes: Matrix Metalloproteinases and Their Multifaceted Roles in Neurodegenerative Diseases
Published 2015-01-01“…Neurodegeneration is a chronic progressive loss of neuronal cells leading to deterioration of central nervous system (CNS) functionality. …”
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177
Assessment of clinical prognosis in autoimmune encephalitis: Girona score
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178
Therapeutic Actions of the Thiazolidinediones in Alzheimer’s Disease
Published 2015-01-01“…However, in this review, we will discuss several cellular targets, in which TZDs can be acting against the neurodegeneration.…”
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179
The Endotoxin-Induced Neuroinflammation Model of Parkinson's Disease
Published 2011-01-01“…Although the exact cause of the dopaminergic neurodegeneration remains elusive, recent postmortem and experimental studies have revealed an essential role for neuroinflammation that is initiated and driven by activated microglial and infiltrated peripheral immune cells and their neurotoxic products (such as proinflammatory cytokines, reactive oxygen species, and nitric oxide) in the pathogenesis of PD. …”
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180
Cox-2 Plays a Vital Role in the Impaired Anxiety Like Behavior in Colchicine Induced Rat Model of Alzheimer Disease
Published 2016-01-01“…The anxiety status is changed along with memory impairments in intracerebroventricular colchicine injected rat model of Alzheimer Disease (cAD) due to neurodegeneration, which has been indicated to be mediated by inflammation. …”
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