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Calcium/calmodulin-dependent protein kinase II α and β differentially regulate mammalian sleep
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Endogenous Estrogen Influences Predator Odor-Induced Impairment of Cognitive and Social Behaviors in Aromatase Gene Deficiency Mice
Published 2021-01-01“…Taken together, our results indicate that TMT exposure can cause cognitive and social behavior impairments as well as change catecholamine metabolism in WT mice, and endogenous estrogen deficiency might desensitize the behavioral and neurochemical responses to TMT in Ar+/- mice.…”
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Manganese Inhalation as a Parkinson Disease Model
Published 2011-01-01“…Our data provide evidence that Mn2+/Mn3+ mixture inhalation produces similar morphological, neurochemical, and behavioral alterations to those observed in PD providing a useful experimental model for the study of this neurodegenerative disease.…”
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Pentoxifylline Neuroprotective Effects Are Possibly Related to Its Anti-Inflammatory and TNF-Alpha Inhibitory Properties, in the 6-OHDA Model of Parkinson’s Disease
Published 2015-01-01“…At the next day, they were euthanized and their striata processed for neurochemical (DA and DOPAC determinations), histological, and immunohistochemical (Fluoro-Jade, TH, DAT, OX-42, TNF-alpha, COX-2, and iNOS) studies. …”
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Tetrahydrobiopterin as a rheostat of cell resistance to oxidant injury
Published 2025-02-01“…Tetrahydrobiopterin (BH4) deficiency is caused by genetic abnormalities that impair its biosynthesis and recycling, which trigger neurochemical, metabolic, and redox imbalances. Low BH4 levels are also associated with hypoxia, reperfusion reoxygenation, endothelial dysfunction, and other conditions that are not genetically determined. …”
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Conducting polymer-based electrochemical sensors: Progress, challenges, and future perspectives
Published 2025-08-01“…Conducting polymer-based electrochemical sensors has affectivity in neurochemical and pathogen sensing, which is essential for brain function and mental health.…”
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The neuroendocrine stress-response in insects: the history of the development of the concept
Published 2017-12-01“…The similarity in the neurochemical and physiological changes in invertebrates and vertebrates in response to a stressful influence indicates that the response to a stressor is a complex of ancient mechanisms preserved in evolution. …”
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Serum choline, leptin and interleukin-6 levels in fibromyalgia syndrome-induced pain: a case–control study
Published 2025-02-01“…Conclusions This research highlights FMS's complex nature, involving neurochemical, immunological, and nutritional factors. …”
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Pretreatment With Fragments of Substance-P or With Cholecystokinin Differentially Affects Recovery From Sub-Total Nigrostriatal 6-Hydroxydopamine Lesion
Published 1999-01-01“…Given these relations, we asked here whether pre-lesion treatment with either a C- or an N-terminal fragment of substance P might differentially affect the behavioral and neurochemical outcome of nigrostriatal dopamine lesions. …”
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Oral Administration of Ethanol Extract of Myristica fragrans Elicited Hyperactivity, Anxiety and Reduced Dopamine Level in Rats
Published 2024-12-01“…Brain samples were harvested and homogenized for neurochemical analysis of dopamine using a dopamine kit. …”
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The Neurogenic Effects of Pasak bumi (Eurycoma longifolia Jack) and Seluang Fish (Rasbora spp.) in Malnutrition-Induced Rat
Published 2024-09-01“…Abstract Early developmental malnutrition exerts adverse effects on the structural, neurochemical, and neurophysiological maturation of cerebral cells by disrupting the process of neurogenesis. …”
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Electroencephalogram biomarkers as predictors of mortality and functional recovery in patients with severe traumatic brain injury: Protocol study
Published 2025-06-01“…The trauma triggers inflammatory and neurochemical changes that exacerbate neuronal damage, resulting in neuropsychiatric complications. …”
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Neuroanatomical and functional substrates of the short video addiction and its association with brain transcriptomic and cellular architecture
Published 2025-02-01“…This study offers a comprehensive framework integrating structural, functional, and neurochemical evidence to highlight the neural-transcriptomic underpinnings of SVA symptoms in a non-clinical population.…”
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Nanosensor-based imaging of realtime dopamine release in neurons derived from iPSCs of patients with Parkinson's disease
Published 2025-04-01“…Despite its important role in neuronal function, the impact of DA release/uptake on neurochemical imbalances during neuronal development remains unclear. …”
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Co-administration of coenzyme Q10 and curcumin mitigates cognitive deficits and exerts neuroprotective effects in aluminum chloride-induced Alzheimer's disease in aged mice
Published 2025-01-01“…AlCl3 exposure elevated AchE levels in mice brains vs. treatment. This neurochemical alteration was notably reversed in the dual-treatment group. …”
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Does semaglutide reduce alcohol intake in Danish patients with alcohol use disorder and comorbid obesity? Trial protocol of a randomised, double-blinded, placebo-controlled clinica...
Published 2025-01-01“…A subgroup of the patients will have structural, functional and neurochemical brain imaging performed at baseline and after 26 weeks of treatment. …”
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Haploinsufficiency of PDE2A causes in mice increased exploratory behavior associated with upregulation of neural nitric oxide synthase in the striatum
Published 2025-02-01“…However, neurological and neurochemical effects of PDE2A deficiency are poorly understood. …”
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1-(5-ACETYL-3-METHYL-6-PHENYL-5H-[1,2,4]TRIAZOLO [3,4-b][1,3,4]THIADIAZIN-7-YL)-ETHANONE: DOSE-DEPENDENCE OF ANALGESIC EFFECT, LACK OF OPIOIDERGIC MECHANISM OF ACTION, EFFECT ON BE...
Published 2023-12-01“…Therefore, the opioidergic mechanism is not involved in the analgesic effect of the IFT_247 compound, however, the subtle neurochemical mechanism of the analgesic effect of the IFT_247 compound needs further clarification. …”
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Exploring Azithromycin’s Neuroprotective Role in Traumatic Brain Injury: Insights into Cognitive and Motor Recovery and Neuroinflammatory Modulation
Published 2025-01-01“…Behavioral tests (Morris water maze, rotarod, and open field tests) were performed to assess cognitive and motor functions. Neurochemical analyses included oxidative stress markers (GSH, SOD, MDA, catalase), inflammatory cytokines (TNF-α, IL-1β), apoptotic markers (caspase-3, Bax, Bcl-2), mitochondrial complexes (complex I, II, III, IV, and V), and the transforming growth factor- beta (TGF-β) as a neurofilament marker. …”
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