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561
Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity
Published 2025-01-01“…Abstract Identifying cell types and brain regions critical for psychiatric disorders and brain traits is essential for targeted neurobiological research. By integrating genomic insights from genome-wide association studies with a comprehensive single-cell transcriptomic atlas of the adult human brain, we prioritized specific neuronal clusters significantly enriched for the SNP-heritabilities for schizophrenia, bipolar disorder, and major depressive disorder along with intelligence, education, and neuroticism. …”
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562
Cholecystokinin facilitates the formation of long-term heterosynaptic plasticity in the distal subiculum
Published 2025-02-01“…In conclusion, our findings prove a crucial role of CCK in regulating neurobiological functions in the SUB region.…”
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563
An Overview of Diabetes Management in Schizophrenia Patients: Office Based Strategies for Primary Care Practitioners and Endocrinologists
Published 2015-01-01“…Multiple factors including genetic risk, neurobiologic mechanisms, psychotropic medications, and environmental factors contribute to the increased prevalence of diabetes. …”
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564
Effect of open and locked exercise on cognitive function in older adults
Published 2025-02-01“…It discuss the specific effects and related neurobiological mechanisms of different types of exercise on cognitive function (including attention, memory, executive ability, etc.) in the elderly. …”
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565
Brain dynamics and personality: a preliminary study
Published 2024-12-01“…Additionally, this preliminary finding suggests a neurobiological basis for adaptive social behaviors. Although the results are preliminary, this study provides initial insights into the intricate relationship between brain dynamics and personality, thus laying the groundwork for further research in this emerging field using a dynamic network analysis of the functional activity of the brain.…”
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566
Seeding Stress Resilience through Inoculation
Published 2016-01-01“…Focus of the bulk of relevant neurobiological research at present remains on negative aspects of health and psychological outcomes of stress exposure. …”
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567
Proteostasis and Mitochondrial Role on Psychiatric and Neurodegenerative Disorders: Current Perspectives
Published 2018-01-01“…We aimed to critically analyze the available findings regarding the neurobiological implications of proteostasis on the development of neurodegenerative and psychiatric diseases, considering the mitochondrial role. …”
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568
On the improvement of schizophrenia detection with optical coherence tomography data using deep neural networks and aggregation functions
Published 2024-12-01“…Abstract Schizophrenia is a serious mental disorder with a complex neurobiological background and a well-defined psychopathological picture. …”
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569
Understanding schizophrenia through animal models: The role of environmental stressors
Published 2024-01-01“…Animal models are indispensable tools for understanding the complex neurobiological mechanisms underlying psychosis and for developing new therapeutic approaches. …”
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570
Physical activity and depression
Published 2025-02-01“…Various aspects of physical activity are analyzed, such as the type and intensity of training, their impact on neurobiological and psychosocial functions. The article discusses the benefits of physical activity, including mood improvement, reduction of depressive symptoms, and overall well-being enhancement. …”
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571
Adjudicating between face-coding models with individual-face fMRI responses.
Published 2017-07-01“…We developed and evaluated multiple neurobiologically plausible computational models, each of which predicts a representational distance matrix and a regional-mean activation profile for 24 face stimuli. …”
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572
The OAuth 2.0 Web Authorization Protocol for the Internet Addiction Bioinformatics (IABio) Database
Published 2016-03-01“…Understanding the neurobiological mechanism of behavioral addictions is essential for the development of specific and effective treatments. …”
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573
Modulation of empathic abilities by the interplay between estrogen receptors and arginine vasopressin
Published 2025-01-01“…These findings provide essential insights into the neurobiological underpinnings of empathy, offering new avenues for therapeutic interventions in social cognitive disorders and emotional dysregulation.…”
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574
Sexual dimorphism in the response to antidepressant therapy: Biological basis and clinical implications declaration of competing interests author contributions
Published 2024-01-01“…In contrast, men may exhibit different depressive patterns, characterized by externalizing behaviors and higher suicide rates. Neurobiological studies highlight gender-specific differences in brain structure and function, as well as in neurotransmitter systems, which may impact treatment efficacy and response variability. …”
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575
Rapid lightsheet fluorescence imaging of whole Drosophila brains at nanoscale resolution by potassium acrylate-based expansion microscopy
Published 2024-12-01“…Here we show that at a tile scanning speed of ~1 min/mm3 with 1012 pixels over 14 hours, we image the centimeter-sized fly brain at an effective resolution comparable to electron microscopy, allowing us to visualize mitochondria within presynaptic compartments and Bruchpilot (Brp) scaffold proteins distributed in the central complex, enabling robust analyses of neurobiological topics.…”
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576
Depression in Parkinson’s Disease: The Contribution from Animal Studies
Published 2017-01-01“…Animal studies can help in understanding the neurobiological mechanisms of depression in PD and the pursuit for more effective drugs for its treatment, but they lack the complexity of the disease progression, especially the nondopaminergic degeneration.…”
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577
Functional Role of Adult Hippocampal Neurogenesis as a Therapeutic Strategy for Mental Disorders
Published 2012-01-01“…In this paper, we discuss three major psychiatric disorders, depression, schizophrenia, and drug addiction, in light of preclinical evidence used in establishing the neurobiological significance of adult neurogenesis. We interpret the significance of these results and pose questions that remain unanswered. …”
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578
Can Chaotic Analysis of Electroencephalogram Aid the Diagnosis of Encephalopathy?
Published 2018-01-01“…This finding may be useful to understand the neurobiological phenomena in encephalopathy. These chaotic features are then utilized as feature sets for Support Vector Machine classifier to identify cases of encephalopathy from normal healthy subjects yielding high values of accuracy. …”
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579
Pituitary adenylate cyclase-activating polypeptide plays a role in neuropsychiatric and substance use disorders: sex-specific perspective
Published 2025-02-01“…Studies expand the role of PACAP to substance use disorders (SUD) by demonstrating modulation of PACAP can lead to neurobiological changes induced by nicotine, ethanol, stimulants and opioids. …”
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580
The connecting brain in context: How adolescent plasticity supports learning and development
Published 2025-01-01“…Puberty initiates significant neurobiological changes that amplify adolescents’ responsiveness to their environment, facilitating neural adaptation through processes like synaptic pruning, myelination, and neuronal reorganization. …”
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