Health-related quality of life in patients with multiple sclerosis by Lázaro Aurelio Vázquez Gómez, Carlos Hidalgo Mesa, Benita Mabel Beltrán González, Yunier Broche Pérez, Ana María Mederos Herrera

“…<p><strong>Background:</strong> multiple sclerosis is a disease characterized by outbreaks of disability in any functional system that are produced by inflammation and demyelination of the central nervous system.<br /><strong>Objective:</strong> to determine the health-related quality of life in patients with multiple sclerosis.…”
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Parkinson’s disease and other movement disorders in the context of the SARS-COV-2 pandemic by R. Kaladytė Lokominienė

“… Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is able to invade the human nervous system and can cause headache, nausea, vomiting, febrile seizures, encephalopathy, encephalitis, ataxia or psychiatric disorders, as well as quantitative disturbances of smell and taste which are observed both during the course of Parkinson’s disease and other alpha-synucleinopathies, only in slowly progressive and irreversible manner. …”
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Nanotherapeutic smart approaches for combating Alzheimer’s disease and overcoming existing obstacles: A novel eco-friendly green approach by Ahmed M. Almehdi, Doha H. Aboubaker, Rania Hamdy, Ali El-Keblawy

“…It depends on enhancing the way that medications are distributed pharmacokinetically throughout the central nervous system. Several types of nanoparticles (Nps) are available thanks to nanotechnology, and these Nps could target the brain and have a long half-life with few systemic side effects and motor problems. …”
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Balancing CIK Cell Cancer Immunotherapy and PPAR Ligands: One Potential Therapeutic Application for CNS Malignancies by Kira Vordermark, JingJing Pu, Amit Sharma, Jarek Maciacyzk, Ingo G. H. Schmidt‐Wolf

“…Equally important are the hints suggesting peroxisome proliferator‐activated receptors (PPARs) ligands being co‐expressed in the central nervous system (CNS). This provides a rationale about investigating the possible synergistic effect of CIK cells and PPARs. …”
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Pituitary adenoma: literature review and association with TAS2R16 (rs978739, rs1357949) gene polymorphisms by E. Pileckaitė, G. Gedvilaitė, L. Kriaučiūnienė

“…PA is one of the most common tumors of the central nervous system. PA is differentiated by hormone secretion into non-secretory (non- functional) and secretory (functionally active). …”
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Modeling the Effect of Cannabinoid Exposure During Human Neurodevelopment Using Bidimensional and Tridimensional Cultures by Enrique Estudillo, Jorge Iván Castillo-Arellano, Emilio Martínez, Edgar Rangel-López, Adolfo López-Ornelas, Roxana Magaña-Maldonado, Laura Adalid-Peralta, Iván Velasco, Itzel Escobedo-Ávila

“…Here, we review the information to date on the clinical studies about the impact of exogenous cannabinoid consumption on human brain development and how exogenous cannabinoids alter nervous system development in humans using cultured pluripotent stem cells as 2D and 3D platforms to recapitulate brain development.…”
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Management of Recurrent Ventriculoperitoneal Shunt Infections in Adult Patients by Neval Elgormus, Yusuf Elgormus, Bagnu Dundar, Fatma Bozkurt, Huseyin Dogu, Hafize Uzun

“…Of the patients in the SVPS infection group, 49% were treated with combinations with carbapenem; of the patients in the RVPS infection group, 84.4% were treated in the same way. Central nervous system (CNS) tuberculosis as the etiology of hydrocephalus; short duration of antibiotics used for treatment; high cerebrospinal fluid (CSF) protein and blood C-reactive protein (CRP) levels; and prolonged use of prophylactic antibiotics were found to be related to an increased rate of recurrent infection occurrence. …”
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Stem Cells from Human Exfoliated Deciduous Teeth Attenuate Trigeminal Neuralgia in Rats by Xiaofeng Bai, Xuedi Zhang, Chun Wang, Yao Liu, Xuemei Liu, Yu Fan, Xia Zhang

“…Trigeminal neuralgia is an incurable progressive nervous system disease that can last for several months or years. …”
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α-Synuclein fibrils enhance HIV-1 infection of human T cells, macrophages and microglia by Lia-Raluca Olari, Sichen Liu, Franziska Arnold, Julia Kühlwein, Marta Gil Miró, Ajeet Rijal Updahaya, Christina Stürzel, Dietmar Rudolf Thal, Paul Walther, Konstantin M. J. Sparrer, Karin M. Danzer, Jan Münch, Frank Kirchhoff

“…Despite their importance, the mechanisms allowing HIV-1 entry and replication in the central nervous system (CNS) are poorly understood. Here, we show that α-synuclein and (to a lesser extent) Aβ fibrils associated with neurological diseases enhance HIV-1 entry and replication in human T cells, macrophages, and microglia. …”
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Osteopontin Expression in the Brain Triggers Localized Inflammation and Cell Death When Immune Cells Are Activated by Pertussis Toxin by Maria Cecilia Garibaldi Marcondes, Ryan Ojakian, Nikki Bortell, Claudia Flynn, Bruno Conti, Howard S. Fox

“…Upregulation of osteopontin (OPN) is a characteristic of central nervous system pathologies. However, the role of OPN in inflammation is still controversial, since it can both prevent cell death and induce the migration of potentially damaging inflammatory cells. …”
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Primary cerebral cystic echinococcosis in a child from Roman countryside: Source attribution and scoping review of cases from the literature. by Adriano Casulli, Stefania Pane, Franco Randi, Paola Scaramozzino, Andrea Carvelli, Carlo Efisio Marras, Andrea Carai, Azzurra Santoro, Federica Santolamazza, Francesca Tamarozzi, Lorenza Putignani

“…In a smaller number of cases, larvae may establish in any organ or tissue, including the central nervous system (CNS). Cerebral CE (CCE) is rare but poses serious clinical challenges.…”
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Application of Transcranial Magnetic Stimulation with Electroencephalography in the Evaluation of Brain Function Changes after Stroke by Linhong Mo, Yiqiu Nie, Guiling Wan, Yingbin Zhang, Man Zhao, Jiaojiao Wu, Huiqi Wang, Qing Li, Aixian Liu

“…Possible mechanism: After brain injury, the nervous system can change its structure and function through different ways and maintain it for a certain period of time. …”
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Chlamydophila pneumoniae Infection and Its Role in Neurological Disorders by Carlo Contini, Silva Seraceni, Rosario Cultrera, Massimiliano Castellazzi, Enrico Granieri, Enrico Fainardi

“…The recent deepening of knowledge on the biology and the use of increasingly more sensitive and specific molecular techniques has allowed demonstration of C. pneumoniae in a large number of persons suffering from different diseases including cardiovascular (atherosclerosis and stroke) and central nervous system (CNS) disorders. Despite this, many important issues remain unanswered with regard to the role that C. pneumoniae may play in initiating atheroma or in the progression of the disease. …”
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Clinico-pathological profile of patients with HIV and tuberculosis co-infection by Cheryl Sarah Philipose, Sinchana KM, Haritha Haridas, John Ramapuram, Sharada Rai

“…Opportunistic infections (OIs) other than TB, included 2 cases with oral candidiasis and 1 case with central nervous system (CNS) toxoplasmosis. Two of the HIV-TB co-infected cases were subsequently diagnosed with primary CNS (n = 1) and retroperitoneal lymphoma (n = 1). …”
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Impact of the Timing of Enzyme Replacement Therapy Initiation and Cognitive Impairment Status on Outcomes for Patients with Mucopolysaccharidosis II (MPS II) in the United States:... by Karen S. Yee, David Alexanderian, Yidie Feng, Xiaowei Ren, Bernd Schweikert, Olulade Ayodele

“…Accumulation of glycosaminoglycans results in multisystemic disease manifestations, which may include central nervous system involvement and cognitive impairment (CI). …”
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Remembering what did not happen: the role of hypnosis in memory recall and false memories formation by Donato Giuseppe Leo, Donato Giuseppe Leo, Davide Bruno, Riccardo Proietti, Riccardo Proietti

“…Hypnosis has proved to affect the autonomic nervous system, positively impacting the cardiovascular response. …”
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Cortical Neurotransmitters Measured by Magnetic Resonance Spectroscopy Change Following Traumatic Brachial Plexus Injury by Ryckie G. Wade, Gráinne Bourke, Alexandra M. Olaru, Stephen R. Williams, David Shelley, Sven Plein, Robert D. Bains, James D. Bedford, Lucy E. Homer Newton, Chye Yew Ng, Laura Parkes, Caroline Lea-Carnall

“…In response to injury within the central nervous system, GABA promotes cortical plasticity and represents a potential pharmacological target to improve functional recovery. …”
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Understanding Autoimmune Mechanisms in Multiple Sclerosis Using Gene Expression Microarrays: Treatment Effect and Cytokine-related Pathways by A. Achiron, M. Gurevich, D. Magalashvili, I. Kishner, M. Dolev, M. Mandel

“…Multiple sclerosis (MS) is a central nervous system disease in which activated autoreactive T-cells invade the blood brain barrier and initiate an inflammatory response that leads to myelin destruction and axonal loss. …”
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Atrial Natriuretic Peptide Improves Neurite Outgrowth from Spiral Ganglion Neurons In Vitro through a cGMP-Dependent Manner by Fei Sun, Ke Zhou, Ke-yong Tian, Jie Wang, Jian-hua Qiu, Ding-jun Zha

“…ANP and its receptors are widely expressed in the mammalian nervous system where they could be implicated in the regulation of multiple neural functions. …”
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ATP Induces Disruption of Tight Junction Proteins via IL-1 Beta-Dependent MMP-9 Activation of Human Blood-Brain Barrier In Vitro by Fuxing Yang, Kai Zhao, Xiufeng Zhang, Jun Zhang, Bainan Xu

“…Disruption of blood-brain barrier (BBB) follows brain trauma or central nervous system (CNS) stress. However, the mechanisms leading to this process or the underlying neural plasticity are not clearly known. …”
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