Knockdown MTDH Inhibits Glioma Proliferation and Migration and Promotes Apoptosis by Downregulating MYBL2 by Junqi Fu, Jun Peng, Guolong Tu

“…Glioma is a malignant tumor that often occurs in the adult central nervous system. Metadherin/astrocyte-elevated gene-1 (MTDH) is involved in the development of cancer, but its relationship with glioma remains unclear. …”
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Rapid and simple determination of histamine-N-methyl transferase activity by high-performance liquid chromatography with UV detection by Hajime Inoue, Ken-Ichi Hisamatsu, Miki Yamauchi, Norio Kumagai

“…Therefore, the present method could be applicable for the enzymatic investigation of histamine metabolism in central nervous system or inflammatory reactions.…”
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The immunological perspective of major depressive disorder: unveiling the interactions between central and peripheral immune mechanisms by Wenli Jiao, Jiayi Lin, Yanfang Deng, Yelin Ji, Chuoyi Liang, Sijia Wei, Xi Jing, Fengxia Yan

“…Within the central nervous system, aberrant microglial and astrocytes activation, cytokine imbalances, and compromised blood-brain barrier integrity propagate neuroinflammation, disrupting neurotransmission, impairing neuroplasticity, and promoting neuronal injury. …”
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Brainstem Infarction and Panuveitis due to Sarcoidosis Successfully Treated with Steroid Pulse Therapy by Natsuyo Yoshida-Hata, Shigeko Yashiro, Noritoshi Arai, Sousuke Takeuchi

“…We recommend that steroid pulse therapy be considered to treat patients with sarcoidosis with signs of lesions in the central nervous system.…”
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Late Relapse of Previous Pulmonary Cryptococcosis With Symptoms Resembling Cerebral Infarction: A Case Report by Anatoli Pinchuk, Gernot Geginat, Volker Rickerts, Belal Neyazi, Klaus Peter Stein, Christian Mawrin, I. Erol Sandalcioglu, Ali Rashidi

“…Cryptococcosis, an infection caused by Cryptococcus neoformans and Cryptococcus gattii, predominantly targets the central nervous system (CNS) in patients with AIDS but is not limited to this group. …”
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Baller-Gerold Syndrome. About a Clinical Case and Review of the Literature by Anolys Narciso Piña Rodríguez, Osiris Intento García, Sady Montes Amador

“…She was given parenteral feeding for several days, it was impossible to establish an adequate oral route due to the absence and/or incoordination of the sucking-swallowing reflexes as an expression of her malformations at the central nervous system level. The case is presented due to its low incidence and prevalence, which is why it is considered a rare disease.…”
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Axon regeneration: an issue of translation by Schaeffer, Julia, Belin, Stephane

“…In the mammalian central nervous system (CNS), adult neurons fail to regenerate spontaneously upon axon injury, which leads to a permanent and irreversible loss of neuronal functions. …”
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Noradrenergic Modulation of Cognition in Health and Disease by Olga Borodovitsyna, Matthew Flamini, Daniel Chandler

“…Norepinephrine released by the locus coeruleus modulates cellular processes and synaptic transmission in the central nervous system through its actions at a number of pre- and postsynaptic receptors. …”
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Approaches to the Modulation of Abdominal Pain by Emeran A Mayer, Tony Lembo, Lin Chang

“…Regardless of the primary pathophysiology underlying functional gastrointestinal disorders (ie, central versus peripheral), different pharmacological strategies targeted at different sites in the periphery or within the central nervous system may become effective therapies in the future.…”
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The Microbiome-Gut-Brain Axis, Nutrition and Parkinson’s Disease by Jevgenija Guk, Rūta Kaladytė Lokominienė, Dalius Jatužis

“…According to Braak’s hypothesis, an unknown pathogen in the gastrointestinal tract may initiate the production of pathogenic α synuclein, which would subsequently spread to the central nervous system. The microbiome-gut-brain axis may be implicated in this process, whereas nutrition can be one of the modifiable regulatory variables. …”
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Vulvar Malignancy in Neurofibromatosis Syndrome by Angela Musella, Innocenza Palaia, Lavinia Domenici, Assunta Casorelli, Angela Martoccia, Pierluigi Benedetti Panici

“…Type 1 neurofibromatosis (NF1) is a dominantly inherited neurologic disorder that affects primarily the skin, bones, and peripheral nervous system. It may be associated with a variety of clinical manifestations including cafe-au-lait spots, skinfold freckling, Lisch nodules, and visceral neurofibromas. …”
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Immune Challenge Alters Reactivity of Hippocampal Noradrenergic System in Prenatally Stressed Aged Mice by Gayane Grigoryan, Niklas Lonnemann, Martin Korte

“…Prenatal stress (PS) has long-term sequelae for the morphological and functional status of the central nervous system of the progeny. A PS-induced proinflammatory status of the organism may result in an impairment of both hippocampal synaptic plasticity and hippocampus-dependent memory formation in adults. …”
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Bifurcation Analysis and Synchronous Patterns between Field Coupled Neurons with Time Delay by Li Zhang, Xinlei An, Jiangang Zhang, Qianqian Shi

“…Neurons encode and transmit signals through chemical synaptic or electrical synaptic connections in the actual nervous system. Exploring the biophysical properties of coupling channels is of great significance for further understanding the rhythm transitions of neural network electrical activity patterns and preventing neurological diseases. …”
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A Lip Lump: An Unexpected Histological Diagnosis of a Lip Schwannoma by Thomas Haigh, John Raad Glore, David Gouldesbrough, Winson Wong

“…In the 2016 World Health Organisation Classification of Central Nervous System, they are classified as a tumour of the cranial and paraspinal nerves, Schwannoma 9560/0. …”
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Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection by Ebru Kacmaz, Gurkan Bozan, Kursat Bora Carman, Omer Kilic, Mehmet Ozgur Arslanoglu, Ugur Toprak, Aslı Kavaz Tufan, Coskun Yarar, Ener Cagri Dinleyici

“…Acute disseminated encephalomyelitis (ADEM) is an inflammatory, demyelinating, and rapidly progressive disorder of the central nervous system. This condition is also known as postinfectious encephalomyelitis, and it is characterized by multifocal lesions in the brain and spinal cord with widespread neurological findings. …”
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Neurosurgical aspects of marble bone disease: treatment modalities and outcome by Mahmoud Mohammed Gamal, Roshdy Elkhayat, Hassan Mohammed Hassan

“…This causes the body to produce an abnormal amount of bone that are evident in radiographic findings and cause problems with the body systems, particularly the nervous system. Osteopetrosis has 3 types of genetic inheritance either malignant autosomal recessive (ARO) which occur in childhood, intermediate ARO which occur in adolescence, and benign autosomal dominant osteopetrosis which occur in adults. …”
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Using Protein Painting Mass Spectrometry to Define Ligand Receptor Interaction Sites for Acetylcholine Binding Protein by Alexandru Graur, Natalie Erickson, Nadine Kabbani

“…Nicotinic acetylcholine receptors (nAChRs) are a family of ligand-gated ion channels expressed in nervous and non-nervous system tissue important for memory, movement, and sensory processes. …”
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Successful Treatment of Posttransplant EBV-Associated Lymphoma and Plasmacytoma Solely Localized to the CNS by Per Boye Hansen, Signe Ledou Nielsen

“…Two patients with diabetic nephropathy were diagnosed with primary central nervous system posttransplant Epstein-Barr-virus-associated lymphoproliferative disorder (PTLD) 3 years after renal transplantation. …”
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CHEMOTYPE VERBOCCIDENTAFURAN IN Baccharis punctulata (Asteraceae): FURANIC SESQUITERPENES CORRELATION AND MOLECULAR DOCKING INTO THE BENZODIAZEPINE RECEPTOR by Jociani Ascari, Murilo S. de Oliveira, André L. Rüdiger, Elaine Elisabetsky, Domingos S. Nunes, Jorge Iulek, Dilamara R. Scharf, Gustavo Heiden

“…The results suggest that both compounds 1 and 2 must have affinity for the cavity at a1-y2 interface and support the development of pharmacological research on the compound verboccidentafuran 1 as a drug candidate for modulating the GABA/benzodiazepine complex in the central nervous system.…”
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Cerebrovascular ageing: how zebrafish can contribute to solving the puzzle by Guy Malkinson, Guy Malkinson, Catarina M. Henriques, Catarina M. Henriques

“…The leading cause of morbidity in Europe are diseases of the circulatory system and diseases of the nervous system and cognitive disorders are among the top-ten. …”
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