Coordinated neuron-glia regeneration through Notch signaling in planarians. by M Lucila Scimone, Bryanna Isela-Inez Canales, Patrick Aoude, Kutay D Atabay, Peter W Reddien

“…Some animals can regenerate large missing regions of their nervous system, requiring mechanisms to restore the pattern, numbers, and wiring of diverse neuron classes. …”
Get full text

Astrocyte-Secreted Matricellular Proteins in CNS Remodelling during Development and Disease by Emma V. Jones, David S. Bouvier

“…Despite being well described in the context of nonneuronal tissues, recent studies have revealed that these molecules may also play instrumental roles in central nervous system (CNS) development and diseases. In this minireview, we discuss the matricellular protein families SPARC (secreted protein acidic and rich in cysteine), Hevin/SC1 (SPARC-like 1), TN-C (Tenascin C), TSP (Thrombospondin), and CCN (CYR61/CTGF/NOV), which are secreted by astrocytes during development. …”
Get full text

State-of-the-Art Techniques to Causally Link Neural Plasticity to Functional Recovery in Experimental Stroke Research by Anna-Sophia Wahl

“…Research of recent years has shown the tremendous potential of the central nervous system to react to noxious stimuli such as a stroke: Increased plastic changes leading to reorganization in form of neuronal rewiring, neurogenesis, and synaptogenesis, accompanied by transcriptional and translational turnover in the affected cells, have been described both clinically and in experimental stroke research. …”
Get full text

Cardiac-Autonomic Imbalance and Baroreflex Dysfunction in the Renovascular Angiotensin-Dependent Hypertensive Mouse by Bianca P. Campagnaro, Agata L. Gava, Silvana S. Meyrelles, Elisardo C. Vasquez

“…Finally, we highlight the relationships between angiotensin and peripheral and central nervous system areas of cardiovascular control and oxidative stress in the 2K1C hypertensive mouse.…”
Get full text

The role of glial cells in neuralgia: a bibliometric exploration by Ting He, DongDong Wang, Linman Wu, Liuyin Jin

“…Neuropathic pain is a chronic pathological pain caused by nervous system damage, characterized by complex mechanisms and limited treatment efficacy. …”
Get full text

Update on Peripheral Arterial Vasodilation, Ascites and Hepatorenal Syndrome in Cirrhosis by Mladen Knotek, Boris Rogachev, Robert W Schrier

“…In cirrhosis of the liver, according to the peripheral arterial vasodilation hypothesis, relative underfilling of the arterial tree triggers a neurohumoral response (activation of renin-angiotensinaldosterone system, sympathetic nervous system, nonosmotic release of vasopressin) aimed at restoring circulatory integrity by promoting renal sodium and water retention. …”
Get full text

Impact of Retinoic Acid on Immune Cells and Inflammatory Diseases by Luana de Mendonça Oliveira, Franciane Mouradian Emidio Teixeira, Maria Notomi Sato

“…Although vitamin A is crucial for maintaining homeostasis at the intestinal barrier and equilibrating immunity and tolerance, including gut dysbiosis, retinoids perform a wide variety of functions in many settings, such as the central nervous system, skin aging, allergic airway diseases, cancer prevention and therapy, and metabolic diseases. …”
Get full text

SDNN/RMSSD as a Surrogate for LF/HF: A Revised Investigation by Hui-Min Wang, Sheng-Chieh Huang

“…Through a time-frequency transformation, the ratio of low- and high-frequency power LF/HF represents the sympatho-vagal balance of the autonomic nervous system (ANS). Some research claimed that SDNN/RMSSD was a good surrogate for LF/HF. …”
Get full text

Nephrological problems in a child with Aicardi-Goutières syndrome by Małgorzata Piejak, Zuzanna Hus, Adam Bujanowicz, Piotr Skrzypczyk, Joanna Samotyjek, Beata Jurkiewicz, Hanna Szymanik-Grzelak, Mariusz I. Furmanek, Małgorzata Pańczyk-Tomaszewska

“…Aicardi-Goutières syndrome (AGS) is a rare genetic disorder characterized by excessive interferon-alpha production, leading to central nervous system damage, manifesting as subacute encephalopathy in infancy. …”
Get full text

Cysticercosis Involving Muscle of Mastication: A Review and Report of Two Cases by Sarbjeet Singh, V. Sreenivasan, Kanika Garg, Nikhel Dev Wazir, Jaspal Singh Rajput, Pawandeep Sandhu Virk

“…It is a common disease in developing countries where it is also endemic. The central nervous system (CNS) is the most important primary site of infection and the disease can present with solitary or multiple space occupying lesions. …”
Get full text

Glioblastoma Multiforme Stem Cells by Irena Dimov, Deasanka Tasic-Dimov, Irena Conic, Vladisav Stefanovic

“…However, the achievement of efficient GBMSC targeting also requires an adequate understanding of the unique microenvironment, and the relationship with the immune system in the central nervous system (CNS) and CNS tumors. The endogenous immune regulation is likely to limit or abrogate the efficacy of the host's immune response, as well as the developed immunotherapeutic strategies at present. …”
Get full text

Everyday and Exotic Foodborne Parasites by Marilyn B Lee

“…Also of concern is toxoplasmosis in AIDS patients, which may lead to toxoplasmosis encephalitis, the second most common AIDS-related opportunistic infection of the central nervous system. Exotic parasites (ie, those acquired from abroad or from imported food) are of growing concern because more Canadians are travelling and the number of Canada?…”
Get full text

Insulin/IGF-I and Related Signaling Pathways Regulate Aging in Nondividing Cells: from Yeast to the Mammalian Brain by Edoardo Parrella, Valter D. Longo

“…Taken together, these studies indicate that simple model systems will contribute to our comprehension of aging of the mammalian nervous system and will stimulate novel neurotherapeutic strategies in humans.…”
Get full text

Is human cytomegalovirus a potential risk factor for mood disorders? A systematic review and meta-analysis by Zahra Yousefian, Seyedeh Masoumeh Seyedhosseini Tamijani, Hamed Ghazvini, Farzan Kheirkhah, Raheleh Rafaiee, Tahoora Mousavi

“…Because of the persistence of cytomegalovirus (CMV) in the body and nervous system, this virus can be activated when the immune system is weakened and continues to exert its destructive effects throughout life. …”
Get full text

Combination of metagenomic next-generation sequencing and morphology for identifying Coccidioides immitis: a case report by Hong Liu, Kaixin Zhou, Chaoran Zhong, Ming Guan

“…His cerebrospinal fluid (CSF) biochemical markers indicated an infection in the central nervous system. However, repeated routine cultures of the CSF for bacterial detection were all negative. …”
Get full text

Brugada Pattern Electrocardiogram Unmasked with Cocaine Ingestion by M. Chadi Alraies, Mohammed A. R. Chamsi-Pasha, Motaz Baibars, Abdul Hamid Alraiyes, Khaldoon Shaheen

“…Cocaine has powerful central nervous system effects1 and acute cocaine overdose has been associated with hyperthermia, agitation, paranoid ideation, status epilepticus, ventricular fibrillation, ventricular tachycardia, and myocardial infarction (MI). …”
Get full text

Treatment of Postpartum Depression with Neurosteroids by Reda Stankevičiūtė, Robertas Strumila

“… Neurosteroids, such as allopregnanolone, are primarily synthesized substances in the central nervous system which influence processes occurring in the brain. …”
Get full text

Research Progress on the Biosynthesis and Applications of Functional Bile Acids by ZHENG Miao, CHANG Chao, SU Qi, CAI Chenggang, LU Yuyun, ZHAO Minjie, CAI Haiying

“…Bile acid (BA), as an important amphoteric sterol in bile, can regulate glucose and lipid metabolism and homeostasis, intestinal microecology, the intestinal barrier, inflammation, the immune system and the nervous system and other physiological functions through interaction with receptors and the intestinal flora, and consequently affect metabolism and nutritional health in the body. …”
Get full text

Restless Legs Syndrome as the Initial Presentation of Multiple Sclerosis by Ceyla Irkec, Doga Vurallı, Sebnem Karacay Ozkalaycı

“…The restless legs syndrome (RLS) is a common central nervous system disorder. It is characterized by complaints of unpleasant sensation in the legs occurring during periods of leg inactivity which worsen or only occur in the evening or at night and relieved partially or totally by movement. …”
Get full text

A variety of clinical presentations of eosinophilic granulomatosis with polyangiitis: a comprehensive review by Agata Sebastian, Joanna Kosałka-Węgiel

“…In addition to these characteristic symptoms, EGPA can affect important organs such as the skin, kidneys, heart, sinuses, gastrointestinal tract, and nervous system. Given the variability of the clinical presentation, EGPA is challenging to diagnose. …”
Get full text