Valerenic acid ameliorates amphetamine-related neurotoxicity by improving hypothalamus tyrosine hydroxylase and histamine-N-methyl transferase enzymes by Khaled M.M. Koriem, Ammar H.A. Naiem

“…Background: Narcolepsy, obesity, and attention deficit hyperactivity disorder are all treated with amphetamine (a central nervous system stimulant) while valerenic acid (VA) has a pharmacological effect in the central nervous system. …”
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Next generation bioelectronic medicine: making the case for non-invasive closed-loop autonomic neuromodulation by Imanuel Lerman, Yifeng Bu, Rahul Singh, Harold A. Silverman, Anuj Bhardwaj, Alex J. Mann, Alik Widge, Joseph Palin, Christopher Puleo, Hubert Lim

“…Today, invasive or non-invasive closed-loop systems have yet to be developed that dynamically modulate autonomic nervous system function by responding to real-time physiological and molecular signals; it represents a transformative approach to therapeutic interventions and major opportunity by which the bioelectronic field may advance. …”
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Detection of Phosphorylated Alpha-Synuclein in the Muscularis Propria of the Gastrointestinal Tract Is a Sensitive Predictor for Parkinson’s Disease by Goichi Beck, Yumiko Hori, Yoshito Hayashi, Eiichi Morii, Tetsuo Takehara, Hideki Mochizuki

“…Lewy bodies and neurites, the pathological hallmarks of PD, are found in the enteric nervous system (ENS) as well as the central nervous system. …”
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Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain by Hao-Ming Xu, Hong-Li Huang, You-Lian Zhou, Hai-Lan Zhao, Jing Xu, Di-Wen Shou, Yan-Di Liu, Yong-Jian Zhou, Yu-Qiang Nie

“…We have reviewed the latest research on the role of gut microbiota in different nervous system diseases as well as FMT in the context of its application in neurological, psychiatric, and other nervous system-related diseases (Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, epilepsy, autism spectrum disorder, bipolar disorder, hepatic encephalopathy, neuropathic pain, etc.).…”
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Systematic analysis of co-expression network and gene expression profile of differentially expressed lncRNA-mRNA one week after spinal cord injury by Yi Kang, Yijie Song, Zhongju Shi, Qiang Li, Yigang Lv, Mengfan Hou, Cui Ding, Jing Xie, Yongfu Lou, Chi Zhang, Huan Jian, Xueying Li, Hengxing Zhou, Shiqing Feng

“…Spinal cord injury (SCI) is a severe event that occurs in the central nervous system (CNS). Long noncoding RNAs (lncRNAs) have already been proven to play key roles in different diseases of the CNS. …”
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Hippocampal Neurogenesis, Depressive Disorders, and Antidepressant Therapy by Eleni Paizanis, Michel Hamon, Laurence Lanfumey

“…There is a growing body of evidence that neural stem cells reside in the adult central nervous system where neurogenesis occurs throughout lifespan. …”
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Imaging features of intracranial meningiomas with histopathological correlation: a case report and review of literature by R. Montvilaitė, S. R. Letautienė, R. Kvaščevičius, A. Barkauskienė

“… Meningiomas are the most common non-glial tumours of the central nervous system. Most meningiomas are benign; however, ~20% are associated with less favourable clinical outcomes and are considered malignant. …”
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A Unique Case of Relapsed B-Acute Lymphoblastic Leukemia/Lymphoma as an Isolated Omental Mass by Kanchan Kantekure, Furha Cossor, Kenneth B. Miller, Monika E. Pilichowska

“…Extramedullary involvement is frequent, with particular predilection for the central nervous system, lymph nodes, spleen, liver, and testis. …”
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Immunotherapeutic Strategies for Alzheimer's Disease Treatment by Beka Solomon

“…The performance of anti-amyloid-β antibodies in transgenic mice models of AD showed that they are delivered to the central nervous system, preventing and dissolving amyloid-β plaques. …”
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Chronic Pain in Inflammatory Arthritis: Mechanisms, Metrology, and Emerging Targets—A Focus on the JAK-STAT Pathway by Fausto Salaffi, Giovanni Giacobazzi, Marco Di Carlo

“…In the last years, the JAK-STAT pathway has been recognized as a pivotal component both in the inflammatory process and in pain amplification in the central nervous system. This paper provides a summary on pain in inflammatory arthritis, from pathogenesis to clinimetric instruments and treatment, with a focus on the JAK-STAT pathway.…”
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Tissue-Derived Stem and Progenitor Cells by Leora J. Tesche, David A. Gerber

“…In this review, we will expand the current state of research involving select tissue-derived stem cell populations including the liver, central nervous system, and cardiac tissues as examples of the success and challenges in this field of research. …”
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Neuroimmunology of psoriasis: Possible roles for calcitonin gene-related peptide in its pathogenesis by Joshua Kotlyar, Richard D. Granstein

“…The nervous system has a complex interplay with the immune system, especially at barrier sites such as the skin. …”
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Acute Respiratory Failure due to Neuromyelitis Optica Treated Successfully with Plasmapheresis by Massa Zantah, Timothy B. Coyle, Debapriya Datta

“…Neuromyelitis Optica (NMO) is a demyelinating autoimmune disease involving the central nervous system. Acute respiratory failure from cervical myelitis due to NMO is known to occur but is uncommon in monophasic disease and is treated with high dose steroids. …”
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Role of Microglia in CNS Autoimmunity by Tobias Goldmann, Marco Prinz

“…Multiple sclerosis (MS) is the most common autoimmune disease of the central nervous system (CNS) in the Western world. The disease is characterized histologically by the infiltration of encephalitogenic TH1/TH17-polarized CD4+ T cells, B cells, and a plethora of myeloid cells, resulting in severe demyelination ultimately leading to a degeneration of neuronal structures. …”
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Presentation of Bilateral Peripheral Seventh Cranial Nerve Palsy in an HIV Patient by Lisa M. Ruiz, Batool Kirmani

“…These complications are neither limited to a specific location in the nervous system nor a focal time period in the disease’s progression. …”
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Pyogenic Ventriculitis Complicating Aggregatibacter aphrophilus Infective Endocarditis: A Case Report and Literature Review by Gordon W Jung, Michael D Parkins, Deirdre Church

“…Prompt diagnosis and treatment with appropriate culture-directed antibiotics with adequate central nervous system penetration is crucial when managing patients who are suspected of having PV. …”
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Mitochondria-Associated Endoplasmic Reticulum Membranes in Microglia: One Contact Site to Rule Them all by Elisa Navarro, Jorge Montesinos

“…Microglia, the resident immune cells of the central nervous system (CNS), play a crucial role in maintaining tissue homeostasis by monitoring and responding to environmental changes through processes such as phagocytosis, cytokine production or synapse remodeling. …”
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Innate Immunity and Neuroinflammation by Abhishek Shastri, Domenico Marco Bonifati, Uday Kishore

“…Inflammation of central nervous system (CNS) is usually associated with trauma and infection. …”
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Granulomatosis with Polyangiitis Presenting as a Parotid Gland Abscess by Blenda Dias, Daniela Soares, Patrick Sampaio, Mittermayer Santiago

“…However, it may affect other sites such as the skin, central nervous system, eyes, heart, gastrointestinal tract, and liver. …”
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Heat stroke with sepsis: A case report and review of the literature by Suyu Wei, Liang Sun

“…Heat stroke, triggered by excessive heat exposure or intense physical activity, is a medical condition characterized by a rapid rise in core body temperature, central nervous system dysfunction and multiorgan failure. A patient presented with heat stroke and was unconscious. …”
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