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Is reflux hypersensitivity truly a functional gastrointestinal disorder? A retrospective cross-sectional study.
Published 2025-01-01“…There were no significant differences in age, sex, BMI, smoking status, or drinking history among RH, NERD and FH. Functional dyspepsia (FD) symptoms were more prone to exist in FH than in NERD (P < 0.05), whereas hiatal hernia was more prevalent in NERD and RH than in FH (P < 0.05). …”
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On-Demand Therapy with Proton Pump Inhibitors for Maintenance Treatment of Nonerosive Reflux Disease or Mild Erosive Esophagitis: A Systematic Review and Meta-Analysis
Published 2018-01-01“…Subgroup analysis was done based on NERD studies alone and on studies of both NERD and mild EE. …”
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Indicators of Esophageal pH-Impedance Monitoring and High-Resolution Manometry in Patients with Various Forms of Gastroesophageal Reflux Disease
Published 2018-09-01“…The aim of the study is to analyze the regularities of changes in the basic indicators of esophageal pH-impedance monitoring and high-resolution manometry in patients with non-erosive reflux disease (NERD), erosive reflux disease (ERD) and Barrett’s esophagus (BE) in comparison with healthy individuals.Materials and methods. 69 patients were examined, including 19 patients with NERD, 16 patients with ERD, 14 patients with BE and 20 individuals comprising the control group (CG). …”
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Macrophage phenotype after human refluxate exposure, esophageal dysmotility and their correlation with gastroesophageal reflux disease
Published 2022-05-01“…On HRM examination, we showed that DCI (distal contractile integral) in NERD patients was higher than in EE (p = 0.088) and BE (p = 0.076), also LES RP (lower esophageal sphincter resting pressure) in NERD patients was higher than in EE (p = 0.039) and BE (p = 0.012). …”
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Functional heartburn and reflux hypersensitivity syndrome (according to the Rome-IV functional esophageal disease diagnostic criteria)
Published 2018-08-01“…Reflux hypersensitivity of the esophagus that was initially considered as one of the forms of the non-erosive gastroesophageal reflux disease (NERD) in the new criteria system is included in the spectrum of functional esophageal diseases. …”
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Features of the Expression of Second-Type Melatonin Receptors by Esophagus Epiteliocytes in Gastroesophageal Reflux Disease
Published 2020-05-01“…The study included 48 GERD patients, out of whom 37 and 11 people were suffering from non-erosive reflux disease (NERD) and erosive reflux disease (ERD), respectively. …”
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Efficacy of Alginate-Antacid Medication in the Treatment of Patients with Gastroesophageal Reflux Disease
Published 2018-11-01“…According to EGD in the NERD group, inflammation were eliminated in 10 (83.3 %) patients. …”
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Esophageal lesions at irritable bowel syndrome
Published 2015-10-01“…In some cases it allows to carry out differential diagnostics between NERD and functional disorders of the esophagus and the stomach in patients with IBS. …”
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New Parameters for Impedance–pH Monitoring in Diagnosing Gastroesophageal Reflux Disease and Predicting its Severity
Published 2019-05-01“…A statistically significant difference (p = 0.02) was found between the median values of MNBI in patients with ERD, NERD, and the control group. A statistically significant difference (p = 0.0) between the median values of the PSPW index in patients with ERD, NERD and the control group was found as well.Conclusions. …”
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Systemic immune response at gastroesophageal reflux disease
Published 2015-10-01“…Patients with erosive and/or ulcerative esophagitis in comparison to patients with non-erosive reflux disease (NERD), Barret's esophagus and healthy patients had increased expression of proinflammatory cytokines. …”
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Disorders of esophageal clearance in gastroesophageal reflux disease and option of their treatment
Published 2012-04-01“…According to the data of EGDS, pH-metry, non-erosive reflux disease (NERD) was found in 21 patients (70%), erosive GERD — in 9 (30%). …”
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Options of improvement of efficacy of gastroesophageal reflux disease treatment by dioctaedric smectite
Published 2015-10-01“…Dioctaedric smectite appears an effective drug as monotherapy of NERD. The chief advantage in treatment of GERD is ability of the drug to stop all reflux types: acidic, weakly acidic, and weakly alkalinic.…”
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Vegetal and Animal Food Proteins Have a Different Impact in the First Postprandial Hour of Impedance-pH Analysis in Patients with Heartburn
Published 2018-01-01“…Similar results have been observed in the three different subcategories of patients (NERD, HE, and FH). Conclusions. Vegetable proteins are associated with a lower number of refluxes, particularly acid refluxes, and with a reduced number of symptoms during the first postprandial hour. …”
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Contemporary Approaches to the Treatment of Gastroesophageal Reflux Disease
Published 2019-03-01“…Proton-pump inhibitors (PPIs) are used as the main class of drugs for reflux esophagitis and non-erosive reflux disease (NERD), as well as in cases when the disease is characterized by certain specific features (e.g., the presence of night symptoms) and extraesophageal manifestations. …”
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Treatment compliance at initial and maintenance therapy at gastroesophageal reflux disease
Published 2018-08-01“…By results of esophagogastroduodenoscopy and morphological investigation of mucosal biopsies non-erosive reflux disease (NERD) was diagnosed in 32 (38.1%) patients, reflux esophagitis was found in 52 cases (61.9%). …”
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A Randomized Placebo-Controlled N-of-1 Trial: The Effect of Proton Pump Inhibitor in the Management of Gastroesophageal Reflux Disease
Published 2019-01-01“…It included one outpatient at the gastroenterology service in a fourth-level hospital, diagnosed with nonerosive reflux disease (NERD). Yet, his symptoms were heartburn and reflux, and his endoscopic results were normal esophageal mucosa, without hiatal hernia, though pathological pH values. …”
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Ethnographic Blogging: Reflections on a Methodological Experiment
Published 2010-01-01“…In my own study of self-identified ‘geeks’ and ‘nerds,’ ethnographic blogging involved traversing news sites, forums, and other blogs for relevant content, leading to opportunities for dialogue with other bloggers and readers; establishing a persona online as a researcher, which has encouraged subjects to invite me to public and private discussions about their culture and identities; and bringing together online subjects from multiple physical sites, among other opportunities. …”
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