Discovery of Quinazolone Pyridiniums as Potential Broad-Spectrum Antibacterial Agents by Jie Dai, Qianyue Li, Ziyi Li, Zhonglin Zang, Yan Luo, Chenghe Zhou

“…The highly active <b>19a</b> with rapid bactericidal properties displayed imperceptible resistance development trends, negligible hemolytic toxicity, and effective biofilm inhibitory effects. …”
Get full text

Optimization of Distillation Conditions for Improved Recovery of Phthalides from Celery (Apium graveolens L.) Seeds by Adam Kokotkiewicz, Anna Badura, Żaneta Tabaczyńska, Andżelika Lorenc, Adam Buciński, Maria Luczkiewicz

“…Enzyme pretreatment had a negligible effect on essential oil and phthalide yields. …”
Get full text

Silver Nanoparticles: Biosynthesis Using an ATCC Reference Strain of Pseudomonas aeruginosa and Activity as Broad Spectrum Clinical Antibacterial Agents by Melisa A. Quinteros, Ivana M. Aiassa Martínez, Pablo R. Dalmasso, Paulina L. Páez

“…In addition, these Ag-NPs showed negligible cytotoxic effect in human neutrophils suggesting low toxicity to the host.…”
Get full text

Adsorption of Bisphenol A on Peanut Shell Biochars: The Effects of Surfactants by Fang Wang, Qiang Zeng, Wenting Su, Min Zhang, Lei Hou, Zhong-Liang Wang

“…Cetyltrimethyl ammonium bromide (CTAB) showed negligible effect on the adsorption of BPA on BC300, and the inhibition effect of CTAB was stronger with the increase of biochar pyrolysis temperature. …”
Get full text

Effect of the chemical nature of fixed-bed reactor support materials on bioreactor performance and biomass accumulation by B. Sen, M. Torrijos, P. Sousbie, J. P. Steyer

“…The chemical nature of the support material clearly has negligible effect and thus the size, shape, and porosity of the support must be more influential.…”
Get full text

Effects of metal ion implantation (Fe, Ti, Zn and Zr) on mechanical properties, corrosion resistance and biocompatibility of WE43 Mg alloy by Lianhui Li, Zhiqiang Zhang, Dechuang Zhang, Fugang Qi, Yilong Dai, Wenwen Wei, Xiaoping Ouyang

“…All surface-modified samples showed negligible cytotoxicity (0–1) at 12.5% extract concentration. …”
Get full text

Flexural Properties of UHPFRC Beams with an Initial Notch by Younes Baghaei Osgouei, Shahriar Tavousi Tafreshi, Masoud Pourbaba

“…Results showed that finer mesh leads to negligible stiffer results with similar observations for the maximum sustained stress by the modulus of elasticity, compressive strength, and width variations. …”
Get full text

Dual-Converter Active Power Filter with Reduced Dynamic Losses: Control Synthesis and Modelin by A. V. Belousov, Y. V. Skuriatin, N. A. Denysevich

“…In such a case, the currents and voltages consumed from the network at common network connectivity points have an almost perfect harmonic shape; and the phase shift of the network currents relative to the corresponding voltages has a negligible value. It is shown that the organization of the operating mode of converters with different conversion frequencies and rated capacities can significantly reduce the dynamic losses in the switches of active power filters.…”
Get full text

Comparison of speech intelligibility in a real and virtual living room using loudspeaker and headphone presentations by Schütze Julia, Kirsch Christoph, Kollmeier Birger, Ewert Stephan D.

“…Moreover, for the stationary speech shaped interferer, effects of room acoustics were negligible. For a majority of target positions, no difference between the four-channel and the large-scale loudspeaker array were found, with an overall good agreement to the real room. …”
Get full text

Estimation of crossbreeding and genetic parameters for reproductive traits of Boer x Central Highland goats in Ethiopia. by Zeleke Tesema, Belay Deribe, Mekonnen Tilahun, Alemu Kefale, Getachew Worku Alebachew, Kefyalew Alemayehu, Tesfaye Getachew, Damitie Kebede, Mengistie Taye, Solomon Gizaw

“…The recombination effect was negligible and not significant (P>0.05) for all traits examined. …”
Get full text

The relative risk of fatal poisoning by methadone or buprenorphine within the wider population of England and Wales by Dave Marteau, Rebecca McDonald, Kamlesh Patel

“…UK Borders Agency data were taken into consideration and revealed that only negligible amounts of methadone and buprenorphine were seized on entering UK territory between 2007 and 2012, suggesting domestic diversion.Conclusions Our analysis of the relative safety of buprenorphine and methadone for opioid substitution treatment reveals that buprenorphine is six times safer than methadone with regard to overdose risk among the general population. …”
Get full text

Papaverine Enhances the Oncolytic Effects of Newcastle Disease Virus on Breast Cancer In Vitro and In Vivo by Sura Akram, Ahmed Majeed Al-Shammari, Hayder B. Sahib, Majid Sakhi Jabir

“…In vitro, results showed that the combination therapy induces synergistic cytotoxicity and apoptosis against cancer cells with a negligible cytotoxic effect on normal cells. In vivo, combination treatment induced a significant antitumor effect with an obvious regression in tumor size and a remarkable and significant expression of caspase-3, caspase-8, and caspase-9 compared to monotherapies. …”
Get full text

Effect of the overhead height and tilt angle on comprehensive performance of photovoltaic roof based on simulation and experimental methods by Wenheng Zheng, Huihui He, Fuyu Qin, Yuncheng Lan, Yingde Yin

“…The results indicate that adjusting the overhead height slightly affects the daily cooling load difference between conventional and photovoltaic roofs, with negligible impact on overall energy-saving efficiency (less than 0.2 %). …”
Get full text

Optimisation of Ultrasound-Assisted Extraction of Total Phenolics and Flavonoids Content from <i>Centella asiatica</i> by Vimolpa Hiranpradith, Nantawan Therdthai, Aussama Soontrunnarudrungsri, Oumaporn Rungsuriyawiboon

“…Variable interactions were negligible (<i>p</i> > 0.05). The relationship between responses (TPC and TFC) and independent parameters could be expressed as the quadratic models fitted with a Predicted R² of 0.8263 for TPC and 0.9006 for TFC. …”
Get full text

Discrete Element Study of Particle Size Distribution Shape Governing Critical State Behavior of Granular Material by Mingdong Jiang, Daniel Barreto, Zhi Ding, Kaifang Yang

“…Additionally, a decrease in the coefficient of curvature (C_c) would also move the CSL downward but with negligible rotation. However, it is found that the variations in the mean particle size (D₅₀) and coefficient of uniformity (C_u) do not affect the position of the CSL in the <i>e-p</i>′ plane. …”
Get full text

Facile Synthesis of Graphene Oxide/Titanate Nanotube Composites and Their Application for Cobalt(II) Removal by Min-Da Xu, Zhen Jin, Wen-Jie Xie, De-Cai Wang, Guang-Song Xu, Ai-Jing Wang, Ran Zhang, Jian Huang

“…Na+, K+, and Mg2+ ions have shown a negligible effect on the Co(II) adsorption efficiency of the GTNT composites. …”
Get full text

Do health professionals know about overdiagnosis in screening, and how are they dealing with it? A mixed-methods systematic scoping review. by Veerle Piessens, Ann Van den Bruel, An Piessens, Ann Van Hecke, John Brandt Brodersen, Emelien Lauwerier, Florian Stul, An De Sutter, Stefan Heytens

“…HPs' perceptions of overdiagnosis varied widely, from considering it a significant harm to seeing it as negligible. This seems linked to their overall beliefs about the benefits and harms of screening and to their position on offering screening, which varies from discouraging to actively promoting it. …”
Get full text

North Africa in the Foreign Policy of Catherine II by A. I. Berezhnov

“…Prior to gaining maritime access to the Black and Mediterranean Seas, Russian interaction with North African territories was negligible. However, the geopolitical landscape of Catherine's era prompted the necessity of engaging with Egypt, Algeria, Morocco, Tunisia, and Tripoli.This article investigates the principal foreign policy initiatives of Russia toward North Africa during the latter half of the 18th century. …”
Get full text

Liberties of the genome: insertions of mitochondrial DNA fragments into nuclear genome by M. V. Golubenko, V. P. Puzyrev

“…The role of NUMTS as a cause of hereditary diseases is negligible, since only a few cases of diseases caused by NUMTS have been described so far. …”
Get full text

Tasks scheduling with different structures in cloud manufacturing according to the time and cost of transportation and the task arrival time by Zohre Kiapasha, Ali Salmasnia

“…Furthermore, existing scheduling models in the cloud manufacturing literature tend to assume that all tasks are available at time zero and that the logistics time/cost among enterprises is negligible. Therefore, in this study, an optimization model with three objective functions of task completion time, the cost imposed on the cloud manufacturing system, and the quality of the selected services are developed to get closer to the real world; three features are included in it: 1) the possibility of tasks with two structures, series and parallel, 2) different arrival times of tasks in the cloud manufacturing system, and 3) time/cost of logistics between different enterprises.Methodology: First, six examples with different numbers of tasks and subtasks are designed with both sequential and parallel structures. …”
Get full text