DEmiRNA-mRNA regulatory network reveals miR‐122-5p as a regulatory factor of arginine metabolism in necrotizing enterocolitis by Zhili Ding, Ting Guo, Qiang Tang, Yaqiang Hong, Zhibao Lv, Li Lu, Wenjun Zhuang

Subjects: “…neonatal necrotizing enterocolitis…”
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L-Citrulline in Neonates: From Bench to Bed Side by Dwayne Mascarenhas, Atefeh Mohammadi, Randa Higazy, Julijana Ivanovska, Estelle Gauda, Bonny Jasani

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The Effect of Cord Blood Vitamin D Level on Bronchopulmonary Dysplasia and Other Neonatal Morbidities in Preterm Infants by Elif Koc, Fatih Bolat, Meric Kaymak Cihan

“… OBJECTIVES: We aimed to investigate the relationship between cord 25-hydroxyvitamin D level and bronchopulmonary dysplasia and other neonatal morbidities (sepsis, necrotizing enterocolitis, intraventricular hemorrhage, patent ductus arteriosus, respiratory distress syndrome, retinopathy of prematurity) in preterm neonates. …”
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Intussusception in a Premature Neonate: A Rare Often Misdiagnosed Cause of Intestinal Obstruction by I. Loukas, N. Baltogiannis, C. Plataras, A.-V. Skiathitou, S. Siahanidou, G. Geroulanos

“…In several reports, a significant number of the infants who were included in the study population were believed to have necrotizing enterocolitis (NEC). We present a rare cause of small intestine obstruction in a preterm female infant that can be easily misdiagnosed and confused preoperatively with other clinical entities particular for this period.…”
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Importance of human breast milk in premature infant by Simonetta Costa, Francesca Serrao, Chiara Tirone, Eloisa Tiberi, Mirta Corsello, Francesca Priolo, Milena Tana, Francesca Paola Fusco, Simonetta Frezza, Giovanni Vento

“…Our findings confirmed the several health benefits in preterm infants, including the improvement of neurodevelopmental outcomes and the protection against necrotizing enterocolitis and infections. Many more investigations will be necessary to understand the mechanisms underlying the beneficial association of HBM with neurodevelopmental outcomes and to confirm the beneficial effects of HBM on bronchopulmonary dysplasia. …”
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Splenic Abscess: A Rare Complication of the UVC in Newborn by Ameer Aslam, Emad Sadek Ahmed Shatla, Sameera Imanullah, Elsaid M. A. Bedair

“…The case that is being reported presented with abdominal distension and recurrent desaturation with suspicion of neonatal sepsis versus necrotizing enterocolitis. However, the final diagnosis was splenic abscess as a complication of an inappropriate UVC insertion which was discovered by abdominal ultrasound. …”
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Probiotics and Prebiotics: Role in Prevention of Nosocomial Sepsis in Preterm Infants by Vrinda Nair, Amuchou S. Soraisham

“…Studies on probiotics in premature infants have focused on normalizing intestinal flora, improvement in feeding intolerance, prevention of necrotizing enterocolitis and sepsis. In this paper, we discuss the intestinal bacterial colonization pattern; the rational for probiotics and prebiotic therapy with special focus on the prevention of nosocomial sepsis in preterm infants.…”
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Pneumoperitoneum in a Micropremie: Not Always NEC by Ahmed Khan, Koert de Waal

“…Newborn Meckel's perforation cases often mimic necrotizing enterocolitis, although many present without any feature of peritonitis. …”
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Human milk oligosaccharides: bridging the gap in intestinal microbiota between mothers and infants by Wen Sun, Lin Tao, Chen Qian, Pei-pei Xue, Si-si Du, Ying-na Tao

“…HMOs can enhance intestinal mucosal barrier function and affect the intestinal function of the host through immune function, which has a therapeutic effect on specific infant intestinal diseases, such as necrotizing enterocolitis. In addition, changes in infant intestinal microbiota can reflect the maternal intestinal microbiota. …”
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Dietary Ganglioside Reduces Proinflammatory Signaling in the Intestine by John Janez Miklavcic, Kareena Leanne Schnabl, Vera Christine Mazurak, Alan Bryan Robert Thomson, Michael Thomas Clandinin

“…Restoring proper structure and function to the diseased intestine can resolve inflammation, increase resistance to infection, and improve gut integrity to induce remission of conditions like necrotizing enterocolitis (NEC) and Crohn's disease (CD). Maintaining inactive state of disease may be achieved by reducing the rate that gangliosides are degraded or by increasing intake of dietary ganglioside. …”
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Association of Acute Kidney Injury with Bronchopulmonary Dysplasia in Preterm Infants by Saime Hacer OZDEMIR, Husnu Fahri OVALI

“…Conclusions: AKI was associated with a greater need for resuscitation at birth, a greater need for invasive mechanical ventilation, fewer ventilatorfree days, and a higher incidence of sepsis, patent ductus arteriosus, and necrotizing enterocolitis in premature infants. It was also more frequently associated with fluid-electrolyte imbalance, blood pressure, and hemodynamic disorders in the first postnatal week. …”
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Pharmacological Therapy of Gastroesophageal Reflux in Preterm Infants by Luigi Corvaglia, Caterina Monari, Silvia Martini, Arianna Aceti, Giacomo Faldella

“…Nevertheless, a significantly increased risk of necrotizing enterocolitis and infections has been largely reported in association with their use, thereby leading to an unfavorable risk-benefit ratio. …”
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Perinatal Outcome of Previable Premature Rupture of Membranes Before 24 Weeks of Gestation: A Single-Centered Retrospective Cohort Study by Yasemin Dogan, Ercan Kockaya, Muzeyyen Dilsad Eser, Ayla Gunlemez

“…Neonatal complications were respiratory distress syndrome (n=19; 65%), early sepsis (n=10; 34%), late sepsis (n=5; 17%), bronchopulmonary dysplasia (n=5;17%), retinopathy of prematurity (n=3; 10%), pneumothorax (n=5; 17%), intracranial hemorrhage (n=2; 6%), necrotizing enterocolitis (n=1; 3%) and meningitis (n=1; 3%). …”
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Analysis of Toll-Like Receptors in Human Milk: Detection of Membrane-Bound and Soluble Forms by Chiara Cattaneo, Alice Caramaschi, Elena Uga, Michela Braghin, Gianluca Cosi, Chiara Peila, Maria C. Strozzi, Miriam Sabatini, Diego Gazzolo, Marcello Manfredi, Maria Cavaletto

“…Preterm babies are more susceptible to infections and may succumb to necrotizing enterocolitis (NEC), a gastrointestinal disease which is exacerbated by an excessive inflammatory response after TLR activation. …”
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Altered Intracellular ATP Production by Activated CD4+ T-Cells in Very Preterm Infants by Giulia Aquilano, Maria Grazia Capretti, Francesca Nanni, Luigi Corvaglia, Arianna Aceti, Liliana Gabrielli, Angela Chiereghin, Giacomo Faldella, Tiziana Lazzarotto

“…Low CD4+ T-cell activity at birth is associated with necrotizing enterocolitis (NEC) in the first week of life (p=0.049). …”
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Exploring predisposing factors of hearing loss in prematurely born children: A nationwide case-control study by Pei-Chen Tsao, Hung-Chih Lin, Shang-Po Shen, Yu-Chia Chang

“…Premature infants diagnosed with more than 1 diagnosis of bronchopulmonary dysplasia, necrotizing enterocolitis, and intracerebral hemorrhage were at an increased risk of developing HL. …”
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Prevalence of β-lactam antibiotic resistance of Escherichia coli isolated from a neonatal intensive care unit by Jian Zhou, Jingqian Zhou, Min Chen, Pan Lü, Chunming Jiang

“…Among these, 62 cases presented strains, which were resistant against at least one of seven ß-lactam antibiotics associated with conditions such as ventilator-associated pneumonia (35/62), catheter-associated urinary tract infection (14/62), necrotizing enterocolitis (7/62), skin infection (1/62), and neonatal septicemia (5/62). …”
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Application of Nucleic Acid Reference Material for Rapid Detection of Cronobacter sakazakii (Cronobacter spp.) in Flammulina velutipes by Huandie Yang, Danyang Guo, Leilei Chen, Alexander Suvorov, Qingxin Zhou, Junhua Wang, Xiaofeng Gao, Jinyu Yang, Xiangyan Chen

“…It can cause meningitis, bacteremia, and necrotizing enterocolitis in infants and elderly people with low immunity. …”
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The Human Milk-derived Peptide Drives Rapid Regulation of Macrophage Inflammation Responses in the Neonatal IntestineSummary by Fuqiang Yuan, Xu Han, Masha Huang, Yinglin Su, Yiting Zhang, Mengyuan Hu, Xiang Yu, Weilai Jin, Yun Li, Le Zhang

“…The effects of CASB135-150 on intestinal injury were evaluated in a rat necrotizing enterocolitis (NEC) model. Immunofluorescence analysis was used to determine its distribution, and its impact on NF-κB signaling and inflammation was studied in bone marrow-derived macrophages (BMDMs) and intestinal macrophages. …”
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