Is Intra-articular Platelet-rich Plasma Injection Safe and Effective in Osteoarthritis Knee? A Prospective Study: A Case Series by R Sahaya Jose, N Kattu Bava, M Syed Moosa

“…The release of platelet-derived factors directly at the site of cartilage disease, particularly with interest to knee OA, may stimulate the natural regenerative signaling cascade and enhance tissue healing with further mediation of the anti-inflammatory response. …”
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Development and validation of a machine learning-based model to predict survival in patients with cirrhosis after transjugular intrahepatic portosystemic shuntResearch in context by Binlin Da, Huan Chen, Wei Wu, Wuhua Guo, Anru Zhou, Qin Yin, Jun Gao, Junhui Chen, Jiangqiang Xiao, Lei Wang, Ming Zhang, Yuzheng Zhuge, Feng Zhang

“…Interpretation: This study developed a RF model that better predicted 1-year survival for patients with cirrhosis after TIPS placement than the other scores. Funding: National Natural Science Foundation of China (grant numbers 81900552 and 82370628).…”
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Utility of left atrial and ventricular strain for diagnosis of transthyretin amyloid cardiomyopathy in aortic stenosis by Fumi Oike, Hiroki Usuku, Eiichiro Yamamoto, Kyohei Marume, Seiji Takashio, Masanobu Ishii, Noriaki Tabata, Koichiro Fujisue, Kenshi Yamanaga, Daisuke Sueta, Shinsuke Hanatani, Yuichiro Arima, Satoshi Araki, Seitaro Oda, Hiroaki Kawano, Hirofumi Soejima, Kenichi Matsushita, Mitsuharu Ueda, Toshihiro Fukui, Kenichi Tsujita

“…In clinical baseline characteristics, natural logarithm troponin T was significantly higher in the 99mTc‐PYP scintigraphy‐positive than scintigraphy‐negative group (−2.9 ± 0.5 vs. −3.5 ± 0.8 ng/mL, P < 0.05). …”
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Breeding and genetic aspects of creating productive forms of fast-developing spring bread wheat by B. V. Rigin, E. V. Zuev, V. A. Tyunin, E. R. Shreyder, Z. S. Pyzhenkova, I. I. Matvienko

“…Photoperiodic sensitivity was evaluated under 18-hour (natural day) and at 12-hour (short day) conditions. …”
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Chemical Composition and Larvicidal Activity of Flower Extracts from Clitoria ternatea against Aedes (Diptera: Culicidae) by Darvin R. Ravindran, Madhuri Bharathithasan, Patmani Ramaiah, Mohd Sukhairi Mat Rasat, Dinesh Rajendran, Shakila Srikumar, Intan H. Ishak, Abd Rahman Said, Rajiv Ravi, Mohamad Faiz Mohd Amin

“…Thus, a search for alternative natural compounds is necessary for solving the insecticidal resistance problem using pesticides in the larval stage of vector development as well as creating a chemical-free environment for a healthy society. …”
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Identifikasi Tanaman Obat Indonesia Melalui Citra Daun Menggunakan Metode Convolutional Neural Network (CNN) by Budi Setiyono, Muhammad Riv’an Arif, Qonita Qurratu Aini, Theophil Henry Soegianto, Jasti Ohanna, Ricky Andrean Fernanda Gunawan, Ayu Putri Rizkia

“…Abstract   Indonesia has abundant natural resources, one of which is various types of plants. …”
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Anti-SARS-CoV-2 serology based on ancestral RBD antigens does not correlate with the presence of neutralizing antibodies against Omicron variants by Léa Dépéry, Isabelle Bally, Axelle Amen, Benjamin Némoz, Marlyse Buisson, Laurence Grossi, Aurélie Truffot, Raphaële Germi, Delphine Guilligay, Mélanie Veloso, Antoine Vilotitch, Olivier Epaulard, Patrice Morand, Winfried Weissenhorn, Pascal Poignard, Julien Lupo

“…Adapting serological tests may improve their clinical utility in immunocompromised patients.IMPORTANCEAnti-SARS-CoV-2 serology was developed in 2020 in response to the COVID-19 pandemic to diagnose SARS-CoV-2 infection and monitor an individual’s immunity following natural infection or vaccination. Given the relationship between neutralizing antibody titers and protection against severe infection, many studies have evaluated the correlation between serology tests and neutralization assays in the pre-Omicron era. …”
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Physiology and Pathophysiology of Marathon Running: A narrative Review by Lorin Braschler, Pantelis T. Nikolaidis, Mabliny Thuany, Daniela Chlíbková, Thomas Rosemann, Katja Weiss, Matthias Wilhelm, Beat Knechtle

“…It further positively affects hematopoiesis and cytotoxic abilities of natural killer cells, and may act neuroprotective on a long-term basis. …”
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Exploring the Psychological and Physiological Insights Through Digital Phenotyping by Analyzing the Discrepancies Between Subjective Insomnia Severity and Activity-Based Objective... by Ji Won Yeom, Hyungju Kim, Seung Pil Pack, Heon-Jeong Lee, Taesu Cheong, Chul-Hyun Cho

“…While traditionally assessed through subjective measures such as the Insomnia Severity Index (ISI), the advent of wearable technology has enabled continuous, objective sleep monitoring in natural environments. However, the relationship between subjective insomnia severity and objective sleep parameters remains unclear. …”
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Design, evaluation, and future projections of the NARCliM2.0 CORDEX-CMIP6 Australasia regional climate ensemble by G. Di Virgilio, G. Di Virgilio, J. P. Evans, J. P. Evans, F. Ji, F. Ji, E. Tam, J. Kala, J. Andrys, C. Thomas, D. Choudhury, C. Rocha, S. White, Y. Li, M. El Rafei, R. Goyal, M. L. Riley, J. Lingala

“…NARCliM2.0 is a valuable resource for assessing climate change impacts on societies and natural systems and informing resilience planning by reducing model biases versus earlier NARCliM generations and providing more up-to-date future climate projections utilising CMIP6.…”
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Bias Mitigation in Primary Health Care Artificial Intelligence Models: Scoping Review by Maxime Sasseville, Steven Ouellet, Caroline Rhéaume, Malek Sahlia, Vincent Couture, Philippe Després, Jean-Sébastien Paquette, David Darmon, Frédéric Bergeron, Marie-Pierre Gagnon

“…Algorithmic preprocessing methods, such as relabeling and reweighing data, along with natural language processing techniques that extract data from unstructured notes, showed the greatest potential for bias mitigation. …”
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Organisational Enablers of Artificial Intelligence Adoption in Public Institutions: A Systematic Literature Review by Nina Tomaževič, Eva Murko, Aleksander Aristovnik

“…Firstly, the division of AI literature between natural and social sciences, with the former focusing on technical aspects and the latter on broader organisational themes, may have resulted in an incomplete depiction of the intersection of AI and organisational change. …”
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Alkaloids extracted from Dendrobium officinale grown in diverse environments exhibited robust antioxidative and antiaging activity by Yichen Liu, Arome Solomon Odiba, Qi Yu, Jin Xie, Nkwachukwu Oziamara Okoro, Guiyan Liao, Xinchen Zhu, Bin He, Cheng Jin, Wenxia Fang, Bin Wang

“…The differential responses among DOA variants highlight the importance of the cultivation environment in shaping the bioactivity of natural compounds.…”
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Development and validation of an explainable machine learning model for mortality prediction among patients with infected pancreatic necrosisResearch in context by Caihong Ning, Hui Ouyang, Jie Xiao, Di Wu, Zefang Sun, Baiqi Liu, Dingcheng Shen, Xiaoyue Hong, Chiayan Lin, Jiarong Li, Lu Chen, Shuai Zhu, Xinying Li, Fada Xia, Gengwen Huang

“…Two publicly accessible web tools generated for the optimized model facilitated its utility in clinical settings. Funding: The Natural Science Foundation of Hunan Province (2023JJ30885), Postdoctoral Fellowship Program of CPSF (GZB20230872), The Youth Science Foundation of Xiangya Hospital (2023Q13), The Project Program of National Clinical Research Center for Geriatric Disorders of Xiangya Hospital (2021LNJJ19).…”
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Delay of innate immune responses following influenza B virus infection affects the development of a robust antibody response in ferrets by Thomas Rowe, Ashley Fletcher, Melissa Lange, Yasuko Hatta, Gabriela Jasso, David E. Wentworth, Ted M. Ross

“…ABSTRACT Due to its natural influenza susceptibility, clinical signs, transmission, and similar sialic acid residue distribution, the ferret is the primary animal model for human influenza research. …”
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Work performance, physiological and hemato-biochemical responses in working buffalo with different load weights by Visoky Paján-Jiménez, Fernando D. Pazmiño-Rodríguez, Patricia Roldán-Santiago, Cristian Larrondo-Cornejo, Anna Dutro-Aceves, Luis A. de la Cruz-Cruz

“…The animals always had access to water and natural shade from the African palm. Different variables related to work performance, physiological indicators, and biochemical and hematological responses were recorded 30 minutes before the start of work, immediately after work, and in the morning on the rest day, except for work performance variables, since it was measured immediately after work. …”
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Efficacy and safety of 3D-therapy at HCV-related subcompensated liver cirrhosis (genotype 1b) by P. O. Bogomolov, M. V. Matsiyevich, A. O. Buyeverov, V. D. Beznosenko, Ye. V. Fedosova, M. Yu. Petrachenkova, S. V. Koblov, K. Yu. Kokina, O. S. Kuzmina, N. V. Voronkova

“…Profiling of 3D therapy safety demonstrated that development of serious adverse effects during the treatment is comparable to outcomes at natural course of subcompensated LC in the absence of etiological therapy.…”
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The aptamer BC 007 for treatment of dilated cardiomyopathy: evaluation in Doberman  Pinschers of efficacy and outcomes by Sabine Werner, Gerd Wallukat, Niels‐Peter Becker, Katrin Wenzel, Johannes Müller, Ingolf Schimke, Gerhard Wess

“…Conclusions Treatment with BC 007 for β1‐AAB neutralization was safe, resulted in a long‐lasting reduction of β1‐AAB combined with improved cardiac function and prolonged the survival of DP with DCM. Using a natural large animal model of DCM considered superior to small animal models of immunization‐induced cardiomyopathy, combined with a study design comparable with clinical trials, we believe that our results provide the basis for optimism that treatment with BC 007 might also be effective in human patients with DCM.…”
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Evaluation and Influencing Factors of Urban Blue-Green Space Publicness in Changsha by Zhang Chen, Zhang Nan, Zhu Peijuan, Qin Shuqian, Zhang Yong

“…Urban Blue-Green Spaces (UBGS) are material carriers that support public life and expand social interactions. It is also a natural place to realize the spatial publicness. In the context of the ecological civilization, China has made specific achievements in constructing a UBGS. …”
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Male sex ratio of red tilapia Oreochromis sp. after soaking in different concentrations of coconut milk at larvae stadia by Fajar Maulana, Agus Oman Sudrajat, Andre Permana, Lina Mulyani, Harton Arfah

“…As the use of the 17α-methyltestosterone synthetic hormone for masculinization activities has been limited, natural ingredients are required as a substitute, namely coconut milk. …”
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