EL ROL DE LOS ACTORES PÚBLICOS EN LA CONSTRUCCIÓN DE UN ESPACIO TURÍSTICO: EL CASO DE VILLA EL CHOCÓN by Mariana Suárez

“…Y un segundo período caracterizado por la entrada en acción de un relegado actor de base local: el Municipio, que se afianzará como principal ejecutor de políticas de desarrollo y promoverá un modelo que tiende a re-valorizar el medio natural desde la nueva perspectiva del desarrollo local. …”
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Celastrol promotes DNA damage and apoptosis in uterine corpus endometrial carcinoma via promotion of KAT2B-mediated RBPJ acetylation and repression of MCM4 transcription by Lipeng Pei, Yan Zhu, Wenpeng Li, Bin Xu, Jingli Sun

“…Targeting DNA damage and cell apoptosis are regarded as effective ways for UCEC therapy. Celastrol is a natural anti-cancer product from the Celastraceae plant family, while its role in UCEC has not been investigated. …”
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Distribuição espacial de uma espécie endêmica e insular de Hyalella (Crustacea, Amphipoda) em riachos da Mata Atlântica da ilha de Florianópolis, estado de Santa Catarina by Alaína Sulzbaker, Aurea Luiza Lemes da Silva, Daniela da Silva Castiglioni

“…A espécie foi amostrada no Monumento Natural Municipal da Lagoa do Peri (MONA), no sul da ilha, o qual apresenta um grande manancial de água doce do estado, sendo formado por duas microbacias: Cachoeira Grande e Ribeirão Grande. …”
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Recycling waste biosolids to forest propagation of Pinus leiophylla Schltdl. & Cham by Pedro Sinai Rivera-Torres, Jorge Flores-Velázquez, Miguel Ángel López-López, Abdul Khalil-Gardezi, Carlos Ramírez-Ayala, Erickson Basave-Villalobos

“…The data observed, both for nursery propagation and for the field planting stage, indicate that the use of biosolids provides minerals that assign characteristics that improve the adaptability of the species in the natural environment.  Research Highlights • The discharge of biosolids generated in wastewater treatment plants is becoming an environmental problem. …”
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Preparation of an Intelligent pH Film Based on Biodegradable Polymers for Monitoring the Food Quality and Reducing the Microbial Contaminants by Kumaran Subramanian, Deivasigamani Balaraman, Kumaravel Kaliyaperumal, V. Devi Rajeswari, K. Balakrishnan, P. Ronald Ross, Elumalai Perumal, Pugazhvendan Sampath Renuga, Mani Panangal, Y. Swarnalatha, S. Velmurugan

“…Hydrogel refers to a three-dimensional cross-linked polymeric network made of synthetic or natural polymers that can hold water in its porous structure. …”
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Inhibition of complement system-related gene ITGB2 attenuates epithelial–mesenchymal transition and inflammation in diabetic nephropathy by Jun Peng, Wenqi Zhao, Lu Zhou, Kun Ding

“…The VWF and ITGB2 were both enriched in the pathways of chemokine signaling pathway, CAMs, focal adhesion and natural killer cell-mediated cytotoxicity, and significantly correlated with the activated mast cells, resting NK cells, and macrophages. …”
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La degradación de tierras como eje en la organización de los contenidos en Geografía by María Elena Chiementon, Verónica G. Cortese

“…Los procesos degradatorios son producto de las transformaciones que se introducen en el sistema natural, asociadas sobre todo a la aceleración de la erosión hídrica y ólica, que modifican el equilibrio y la dinámica de las relaciones entre todos sus componentes. …”
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RBM47 promotes cell proliferation and immune evasion by upregulating PDIA6: a novel mechanism of pancreatic cancer progression by Yihui Ma, Enjie Liu, Huijie Fan, Chenfei Li, Pei Huang, Meiying Cui, Zhengyang Wang, Jing Zhou, Kuisheng Chen

“…The RBM47 expression was negatively correlated with natural killer (NK) cell infiltrate in PC. Moreover, RBM47 was predicted to bind to the 3′-UTR region of Protein Disulfide Isomerase Family A Member 6 (PDIA6), an oncogene of the development of PC. …”
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Resilience of Fishery Economy in Fujian Coastal Areas from the Perspective of Institutional Evolution by Leng Yun, Wei Suqiong, You Xiaojun, Ren Zhihuang

“…Three main conclusions are drawn: 1) Under the influence of different types of shocks (the super-typhoon in 2006, the financial crisis in 2008, and the upgrading of the fishing industry in 2017), the output value fluctuates significantly owing to the dual effects of production and supply, and the output is more strongly affected by production and more drastically reflective of natural disasters. 2) A spatial regularity exists in the impact of regional crises (typhoons) on industrial resilience resistance; the closer to the disaster center, the poorer the performance of industrial resilience resistance. …”
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Differential impact of TIM-3 ligands on NK cell function by Xin Zhang, Lazar Vujanovic, Riyue Bao, Robert L Ferris, Tullia C Bruno, Aditi Kulkarni, Hridesh Banerjee, Housaiyin Li, Juncheng Wang, Lawrence P Kane, Pragati Upadhyay, Jennifer L Anderson, Onyedikachi Victor Onyekachi, Lidia M R B Arantes

“…The primary objectives of this study were to assess the prevalence and function of TIM-3+ natural killer (NK) cells in patients with head and neck squamous cell carcinoma (HNSCC), determine whether the four TIM-3 ligands differentially affect TIM-3+ NK cell functions, identify the most immunosuppressive ligand, and evaluate whether targeting ligand-mediated TIM-3 signaling enhances NK cell effector functions.Methods Single-cell RNA sequencing and flow cytometry were used to study the prevalence, phenotypes and function of TIM-3+ NK cells in HNSCC patient tumors and blood. …”
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Low light reduces saffron corm yield by inhibiting starch synthesis by Weijing Yang, Weijing Yang, Xin Li, Xin Li, Fei Chang, Fei Chang, Xue Qiu, Xulong Huang, Xulong Huang, Zhan Feng, Zhan Feng, Jie Yan, Jie Yan, Qinghua Wu, Qinghua Wu, Feiyan Wen, Feiyan Wen, Jin Pei, Jin Pei, Tao Zhou, Tao Zhou

“…In this study, a two-year field experiment was conducted under natural light (NL) and low light (LL, 50% of NL intensity) conditions. …”
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Determination of distance away and depth of transmitters relative to a vertical acoustic telemetry array in the open ocean by Eric V. C. Schneider, Brendan S. Talwar, David M. Bailey, Shaun S. Killen, Dale M. Webber, Courtney E. MacSween, Travis E. Van Leeuwen, Frank I. Smith

“…Conclusions This new array is able to provide two-dimensional (distance away and depth) animal behavior data around natural and anthropogenic moored and free-floating structures in open-ocean environments where bottom depths often exceed transmission (~ 1000 m) and receiver (~ 500 m) range specifications of traditional bottom moored positioning arrays. …”
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Hydrochemical assessment of borehole water in Effurun, Delta state Niger Delta, Nigeria: implications for public health and safety by Odunayo Tope Ojo, Chiaka Joy Ike, Adegoke Ige Aladeboyeje, Olayiwola Grace Olaseeni, Olumuyiwa Femi Adewumi

“…However, concerns about potential contamination from both natural and anthropogenic sources necessitate regular groundwater quality assessments. …”
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The Level of Heavy Metal Contamination in Selected Vegetables and Animal Feed Grasses Grown in Wastewater Irrigated Area, around Asmara, Eritrea by Goitom Kfle, Ghebray Asgedom, Tedros Goje, Felema Abbebe, Lula Habtom, Hagos Hanes

“…The results of the multivariate analysis revealed that Fe, V, Al, Cr, Co, and Pb were controlled by mixed (natural and anthropogenic) sources and Zn, Mo, Cu, Mn, and Cd originated from the anthropogenic source. …”
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Fuzzy Logic-Based Arrival Time Estimation for Indoor Navigation Using Augmented Reality by Muhammad Hidayat Mohammed Sohif, Muhammad Imran Mardzuki, Azhar Mohd Ibrahim, Ahmad Jazlan

“…Mobile applications designed for indoor navigation often rely on expensive and computationally demanding beacons or natural markers to track the user's location along a predetermined path. …”
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First assessment of biofouling assemblages in the northern Red Sea, an important region for marine non-indigenous species transfer by Juan Sempere-Valverde, Juan Sempere-Valverde, Eva Aylagas, Vitaly Syomin, Vitaly Syomin, Marcos A. L. Teixeira, Glafira D. Kolbasova, Glafira D. Kolbasova, Sofía Ruiz-Velasco, Sahar Chebaane, Arthur Anker, João Curdia, Ronald Cadiz, Dylan M. Cottrell, Andrea Desiderato, Luiz F. Andrade, Chakkiath Paul Antony, Carolina Bocanegra-Castano, Matilde Marzucchi, Angelo Poliseno, Doaa Baker, Basmah Alabdulaziz, Flor Torres, Ameer A. Eweida, Ameer A. Eweida, Susana Carvalho, Susana Carvalho

“…As coastal development spreads, it presents both challenges and opportunities, highlighting the need for sustainable, ecosystem-based approaches to protect valuable natural areas. This baseline is essential for future monitoring of biofouling dynamics as the region develops.…”
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The use of Geographic Information Systems as innovative tools for sustainable development strategies and enhancing the efficiency of forest sector entities by Lutsiv Nataliia, Pavlo Chukhna

“…It was found that the use of Sentinel-2 and Landsat satellite data combined with NDVI and EVI indices in GIS systems allows for identifving critical biodiversity zones and making timely management decisions regarding the conservation and restoration of natural resources in these areas. The study characterized the results of modeling various forest management scenarios. …”
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Effects of milk extracellular vesicles from Holstein Friesian and Brown Swiss heat-stressed dairy cows on bovine mammary epithelial cells by S. Castellani, L. Basiricò, A. Maggiolino, C. Lecchi, P. De Palo, U. Bernabucci

“…To this purpose, 8 mid lactation cows, 4 of each breed fed the same diet and kept in the same barn, which experienced the same hyperthermia during a natural heat wave, were chosen to collect 2 milk different samples: under thermoneutrality (TN, d1) and under heat stress (HS, d 8) conditions. …”
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Infection control of Aeromonas hydrophila in catfish (Clarias sp.) using mixture of meniran Phyllanthus niruri and garlic Allium sativum in feed by Dinamella Wahjuningrum, Eka Hidayatus Solikhah, Tatag Budiardi, Mia Setiawati

“… Motile aeromonad septicaemia (MAS) is caused by the bacterium Aeromonas hydrophila. The use of plant (natural materials) such as meniran and garlic can be as an alternative way to inhibit the activity of A. hydrophila by their active substances which have potency as an antibacterial and immunostimulant. …”
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The potential for gene-editing to increase muscle growth in pigs: experiences with editing myostatin by A. C. Dilger, X. Chen, L. T. Honegger, B. M. Marron, J. E. Beever

“…These animals were bred to commercial sires to expand the population and determine potential interactive effects between myostatin mutations and the naturally-occurring g.3072G > A mutation in insulin-like growth factor 2. …”
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